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Macroporous gel particles as robust macroporous matrices for cell immobilization

A new design of robust matrices for cell immobilization is described. Macroporous gels (MGs) with immobilized microbial cells were prepared at subzero temperatures and were formed inside a plastic core (so-called, protective housing). Due to the protective housing the macroporous gel particles with immobilized cells can be used in well-stirred bioreactors. High retained activity of yeast (77-92%)

Estimation of Thermal Networks Using Singular Value Decomposition Method

A model is developed using a thermal network analysis approach. An experimental setup is designed and built to validate the model. The model is based on an inverse thermal network analysis using a singular value decomposition algorithm. The data from the experiments are used to determine the thermal conductances using inverse model's unsteady- and steady-state forms. The model development and expe

Imaging Using Hard X-rays From A Laser-produced Plasma

Imaging of technical and biological objects using hard X-rays from a laser-produced plasma source is demonstrated. Magnification radiography and single-shot imaging of biological samples are feasible with the source, which utilised focused radiation from a short-pulse terawatt laser. Differential imaging with element specificity and a new projection geometry for X-ray radiography are proposed.

Density-dependent male mating harassment, female resistance, and male mimicry.

Genetic variation in female resistance and tolerance to male mating harassment can affect the outcome of sexually antagonistic mating interactions. We investigated female mating rates and male mating harassment in natural populations of a damselfly (Ischnura elegans). This damselfly species has a heritable sex-limited polymorphism in females, where one of the morphs is a male mimic (androchrome fe

Nanowire field-effect transistor

A new processing scheme for the fabrication of sub-100-nm-gate-length vertical nanowire transistors has been developed. InAs transistors with an 11 x 11 nanowire matrix and 80 nm gate length have been realized by this process. The gate length is directly controlled via the thickness of the evaporated gate metal and is thus easily scalable. The demonstrated devices operate in depletion mode, and th

Heme A synthase enzyme functions dissected by mutagenesis of Bacillus subtilis CtaA

Heme A, as a prosthetic group, is found exclusively in respiratory oxidases of mitochondria and aerobic bacteria. Bacillus subtilis CtaA and other heme A synthases catalyze the conversion of a methyl side group on heme 0 into a formyl group. The catalytic mechanism of heme A synthase is not understood, and little is known about the composition and structure of the enzyme. In this work, we have: (i

Density functional study of surface forces in solutions containing star-shaped polymers

Density functional theory is used to study polymer solutions between surfaces in equilibrium with a bulk solution. We investigate the effect on the surface interaction free energy of having star polymers with different numbers of arms. In addition, we consider the role played by the strength of the adsorption potential and the concentration of the polymer molecules. The interaction free energy is

The nurse's role and skills in hypertension care: a review

The aim of this review was to examine studies on nursing in hypertension care to find out the nurse's role and skills. Articles were searched during the period 1966-1997. About 650 abstracts were read, and 148 were selected for examination. Forty-two articles were judged to be relevant for the study. The role of the nurse in programs was described as that of a team member, an educator in nonpharma

Dimeric and monomeric organization of photosystem II - Distribution of five distinct complexes in the different domains of the thylakoid membrane

The supramolecular organization of photosystem II (PSII) was characterized in distinct domains of the thylakoid membrane, the grana core, the grana margins, the stroma lamellae, and the so-called Y100 fraction. PSII supercomplexes, PSII core dimers, PSII core monomers, PSII core monomers lacking the CP43 subunit, and PSII reaction centers were resolved and quantified by blue native PAGE, SDS-PAGE

Tree rings and ice cores reveal C-14 calibration uncertainties during the Younger Dryas

The Younger Dryas interval during the Last Glacial Termination was an abrupt return to glacial-like conditions punctuating the transition to a warmer, interglacial climate. Despite recent advances in the layer counting of ice-core records of the termination, the timing and length of the Younger Dryas remain controversial. Also, a steep rise in the concentration of atmospheric radiocarbon at the on

Familial association of pancreatic cancer with other malignancies in Swedish families

BACKGROUND: The aim of this study was to characterise the familial association of pancreatic cancer with other malignancies. METHODS: Relative risks (RRs) of pancreatic cancer according to family history of cancer were calculated using the updated Swedish Family-Cancer Database, which includes over 11.5 million individuals. Estimates were based on Poisson regression. RRs of tumours for individuals

Assessment of biological prognostic factors provides clinically relevant information in patients with diffuse large B-cell lymphoma-a Nordic Lymphoma Group study.

The purpose of this study was to investigate the prognostic effects of four biological markers, BCL2, TP53, Ki-67, and P-glycoprotein, and their possible clinical relevance in addition to the international prognostic index (IPI) in diffuse large B-cell lymphoma (DLBCL). A total of 405 patients with aggressive lymphoma, stage II-IV, between 18 and 67 years, were randomized in a trial comparing CHOP

Low molecular weight heparin for thromboprophylaxis and epidural/spinal anaesthesia--is there a risk?

This article reviews the problem of bleeding in connection with epidural/spinal anaesthesia, with special emphasis on the use of low molecular weight heparins for thromboprophylaxis. There are methodological difficulties to studying the problem in a scientifically correct way because of the rarity of the complication. However, from the data in the literature there are no indications of an increase

The variance reaction time model

The variance reaction time model (VRTM) is proposed to account for various recognition data on reaction time, the mirror effect, receiver-operating-characteristic (ROC) curves, etc. The model is based on simple and plausible assumptions within a neural network: VRTM is a two layer neural network where one layer represents items and one layer represents contexts. The recognition decision is based o

Effects of Levosimendan on Right Ventricular Afterload in Patients with Acute Respiratory Distress Syndrome: a Pilot Study

OBJECTIVE: Acute respiratory distress syndrome (ARDS) is frequently associated with increased pulmonary vascular resistance and thus with systolic load of the right ventricle. We hypothesized that levosimendan, a new calcium sensitizer with potential pulmonary vasodilator properties, improves hemodynamics by unloading the right ventricle in patients with ARDS. DESIGN: Prospective, randomized, pla

Detection of laminin 5-specific auto-antibodies in mucous membrane and bullous pemphigoid sera by ELISA

Mucous membrane pemphigoid (MMP) is an autoimmune bullous disease that primarily affects mucous membranes leading to a scarring phenotype. MMP patients produce auto-antibodies (auto-ab) that preferentially recognize two components of the dermoepidermal basement membrane zone (BMZ): bullous pemphigoid (BP)180 and laminin 5 (LN5). Since detection of disease-specific auto-ab may be critical for diagn

Combining landslide and contaminant risk: a preliminary assessment

The aim of this paper is to highlight a not yet recognized hazard for mass failure (landslides) of contaminated soils into rivers and to provide an understanding of important interactions of such events. A first effort to investigate the problem is made focusing on the south eastern part of the Gota A"lv river valley, in Sweden, by combining geographical information on potentially contaminated sit