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The impact of foreign board membership on firm value
This study examines the effect of foreign (Anglo-American) board membership on corporate performance measured in terms of firm value (Tobin's Q). Using a sample of firms with headquarters in Norway or Sweden the study indicates a significantly higher value for firms that have outsider Anglo-American board member(s), after a variety of firm-specific and corporate governance related factors have bee
Nitric oxide gives maximal response after coronary artery bypass surgery
The dose-response to inhalation of nitric oxide (NO) after coronary artery bypass surgery was studied in seven patients with normal preoperative lung function and chest radiograms. During postoperative controlled ventilation with PEEP 5 and 10 cmH2O, the patients inhaled NO in concentrations of 2 to 25 ppm, in random order, for 6 to 10 minutes. Hemodynamic and oximetric data were analyzed before,
Evolution of UV-B regulation and protection in plants
Plants have evolved under the influence of UV-B radiation and have acquired systems for monitoring it and investing appropriate resources for protection against it, i.e., filters, quenchers of radicals and reactive oxygen species, and repair systems. An hypothesis for how plants monitor radiation has been presented.
Five-year results in Ewing's sarcoma. The Scandinavian Sarcoma Group experience with the SSG IX protocol
The first Scandinavian protocol for Ewing's sarcoma, SSG IV, resulted in a local control rate of 74% and 5-year metastasis-free survival (MFS) of 43%. The second protocol, SSG IX, was started in order to improve upon these results. It featured four chemotherapy cycles, each consisting of two courses of VAI (vincristine, doxorubicin, ifosfamide) alternating with one course of PAI (cisplatin, doxoru
Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy.
Background: Previous studies support a role of oxygen-free radicals in the development of congestive heart failure (CHF). The aim of this study was to investigate whether lipid peroxidation is increased in CHF patients on modem pharmacological therapy and whether there is a positive correlation between plasma levels of markers of lipid peroxidation and severity of heart failure (HF). Plasma malond
Effects of different doses of adrenocorticotrophic hormone on the serum lipoprotein profile in healthy subjects
Adrenocorticotrophic hormone (ACTH) at pharmacological dosage has marked lipid-lowering effects that may have therapeutic implications. The rationale behind the present investigation was the possible use of ACTH as a lipid-lowering replacement for steroids. Thirty-two healthy individuals were randomly divided into four groups of 8 each. Three ACTH groups received different doses of ACTH(1-24) intr
Amphibian conservation in Central Menabe
The amphibian fauna of the Central Menabe region in Western Madagascar is important in respect to their extraordinary adaptations to the dry forest habitat. This habitat is highly threatened. Until 1990, the dry forest in the west of the island was thought to have been reduced to only 3% of its original extent. New analyses show that this deforestation was ongoing at an alarming rate also in the l
Towards a Green Energy Economy? Assessing policy choices, strategies and transitional pathways
The term ‘Green Energy Economy’ (GEE) received increasing policy and scientific attention following the 2008–2009 global financial crisis, leading to the implementation of numerous ‘Green Growth’ economic stimulus packages that targeted low-carbon energy technologies. These initiatives were portrayed as key elements in the transition to a green economy, in which low-carbon energy systems would pla
Making sense of adsorption : Attempting to explain the adsorption of histatin 5 with models, metaphors, and machines
This thesis summarises two studies in which the main purpose was to find out how and why the amount of the protein histatin 5 that adsorbs to negatively charged surfaces changes with pH and ionic strength. Histatin 5 is an intrinsically disordered saliva protein, and in the oral environment it adsorbs to tooth enamel. The approach here is to simplify the biological system by using an aqueous buffe
Spatial and Physical Splittings of Semilinear Parabolic Problems
För att skapa matematiska beskrivningar av fysiska fenomen inom bland annat naturvetenskap, teknik och medicin används ofta partiella differentialekvationer. Listan med tillämpningar kan göras hur lång som helst: sådana ekvationer kan beskriva hur en snöflinga bildas, hur strukturer deformeras när de utsätts för mekaniska krafter, hur partiklar interagerar på kvantnivå, hur blodet flödar i hjärnanSplitting methods are widely used temporal approximation schemes for parabolic partial differential equations (PDEs). These schemes may be very efficient when a problem can be naturally decomposed into multiple parts. In this thesis, splitting methods are analysed when applied to spatial splittings (partitions of the computational domain) and physical splittings (separations of physical processes)
The translationally relevant mouse model of the 15q13.3 microdeletion syndrome reveals deficits in neuronal spike firing matching clinical neurophysiological biomarkers seen in schizophrenia
AIM: To date, the understanding and development of novel treatments for mental illness is hampered by inadequate animal models. For instance, it is unclear to what extent commonly used behavioural tests in animals can inform us on the mental and affective aspects of schizophrenia.METHODS: To link pathophysiological processes in an animal model to clinical findings, we have here utilized the recent
Temporally fluctuating prey and coexistence among unequal conspecific interferers
Coexistence among unequal conspecific interferers should be unlikely to persist if stronger interferers always experience a relative fitness increment from their higher foraging rates. In this study, we suggest that decreased relative costs to weaker interferers with increasing temporal fluctuations in prey availability may be a mechanism enhancing coexistence of unequal conspecific interferers. P
Digital scoring of haemophilic arthropathy using radiographs: is it feasible?
Small animal imaging with pinhole single-photon emission computed tomography
BACKGROUND. High resolution spatial details of the distribution of activity in three dimensions is required to evaluate the localization and dosimetric properties of radiolabelled monoclonal antibodies in tumors and normal tissues. Planar imaging of small animals with a resolution of 5-10 mm is usually the imaging modality of choice. The authors investigated high resolution single-photon emission
Autism spectrum conditons in myotonic dystrophy type 1: A study on 57 individuals with congenital and childhood forms
Myotonic dystrophy type 1 (DM1) is an autosomal dominant disorder, caused by an expansion of a CTG triplet repeat in the DMPK gene. The aims of the present study were to classify a cohort of children with DM1, to describe their neuropsychiatric problems and cognitive level, to estimate the size of the CTG expansion, and to correlate the molecular findings with the neuropsychiatric problems. Fifty-
Role of group A streptococcal IgG-binding proteins in triggering experimental glomerulonephritis in the rabbit
Our previous studies have indicated that the IgG-binding M-family proteins (IgGBP) of group A streptococci may be involved in eliciting experimental acute poststreptococcal glomerulonephritis (APSGN) in the rabbit. These surface proteins were also found to trigger production of anti-IgG, which might conceivably act to enhance renal deposition of immune complexes (IC). In the present study, a clini
Diagnostic of laser contrast using target reflectivity
Using three different laser systems, we demonstrate a convenient and simple plasma based diagnostic of the contrast of high-power short-pulse lasers. The technique is based on measuring the specular reflectivity from a solid target. The reflectivity remains high even at relativistic intensities above 10(19) W/cm(2) in the case of a high-contrast prepulse-free laser. On the contrary, the specular r
Arbetsledningsrätt och arbetsskyldighet : en komparativ studie av kvalitativ flexibilitet i svensk, engelsk och tysk kontext
Popular Abstract in Swedish Detta arbete behandlar regleringen av arbetsgivarens arbetsledningsrätt och arbetstagarens arbetsskyldighet i svensk, engelsk och tysk rätt i ljuset av arbetslivets ökade flexibilisering. Arbetslivets flexibilisering handlar om att öka anpassningsförmågan och rörligheten, och beskrivs ofta som övergången från den traditionella anställningen till atypiska anställningar. The general aim of this doctoral thesis is to study the legal regulation of the managerial prerogative and how it relates to the employee’s obligation to work in Swedish, English and German law in the light of the increasing flexibilisation of working life. The ongoing flexibilisation of working life is often described as an increase in adaptability and allocative flexibility, and as a shift from