Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is an indolent CD20+ lymphoma. Its scarcity has made clinical trials difficult and there is no consensus on first-line treatment. We conducted a population-based study of all patients diagnosed with NLPHL in Sweden between 2000 and 2014 (N = 158; 41 women and 117 men), focusing on clinical features, therapy and overall survival. The median fe

Release and cellular contents of pro- and anti-inflammatory cytokines, neutrophilic elastase and secretory leukocyte proteinase inhibitor (SLPI) were measured with enzyme-linked immunosorbent assay in peripheral blood mono- and polymorphonuclear cells stimulated with preopsonized yeast cells or lipopolysaccharide. Tumour necrosis factor alpha (TNFα) was also measured with a bioassay. TNFα producti

The association between H. pylori infection and pancreatic cancer risk remains controversial. We conducted a nested case-control study with 448 pancreatic cancer cases and their individually matched control subjects, based on the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, to determine whether there was an altered pancreatic cancer risk associated with H. pylori inf

Traumatic brain injury and hemorrhagic shock is associated with blood-brain barrier (BBB) breakdown and edema formation. Recent animal studies have shown that fresh frozen plasma (FFP) resuscitation reduces brain swelling and improves endothelial function compared to isotonic NaCl (NS). The aim of this study was to investigate whether pooled and pathogen-reduced plasma (OctaplasLG® [OCTA]; Octapha

Background: Despite the theoretical links between eating disorders and perfectionism, the definition of perfectionism in practice is complicated. The present study explored descriptions and experiences of perfectionism described by a transdiagnostic sample of patients. Methods: In-depth, semi-structured interviews were carried out with 15 patients. The interviews were analyzed by Thematic Analysis

BACKGROUND—: Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) occurs in 5-10% of all patients with MI. Clinical trials of secondary prevention treatment in MINOCA patients are lacking. Therefore, the aim of this study was to examine the associations between treatment with statins, renin-angiotensin system blockers, beta-blockers, dual antiplatelet therapy and long-term ca

OBJECTIVES: We examined approaches to reduce sodium content of food served in settings operated or funded by the government of the County of Los Angeles, California.METHODS: We adapted health impact assessment methods to mathematically simulate various levels of reduction in the sodium content of food served by the County of Los Angeles and to estimate the reductions' potential impacts on mean sys

Spatially coupled low-density parity-check codes can be decoded using a graph-based message passing algorithm applied across the total length of the coupled graph. However, considering practical constraints on decoding latency and complexity, a sliding window decoding approach is normally preferred. In order to reduce decoding complexity compared with standard parallel decoding schedules, serial s

In 2 studies with a total of over 300 participants, the Epstein Creativity Competencies Inventory for Individuals (ECCI-i) was shown to be a reliable measuring instrument. In the first of these studies, the test was also shown to be a valid predictor of 2 measures of creative expression. The test is derived from empirical research on the creative process in individuals, which suggests that creativ

Public perception of the underlying causes of anthropogenic climate change is a complex and subjective issue that is critical to effective risk communication. This issue is important to scientists and policymakers because of the role of individual perceptions in influencing their protective behaviour towards risk (e.g., the adoption of climate risk reduction and mitigation strategies). This cross-

Some species of long-distance migrant birds are thought to follow spatiotemporal patterns of high food availability during the non-breeding season, a strategy termed "itinerancy," instead of being sedentary in one specific site. We tracked the migration of a small Eurasian songbird, the Common Redstart (Phoenicurus phoenicurus), using archival light-level geolocators. The birds showed a distinct c

The paper reports experimental results on the intonation of wh- and yes/no-questions in Tokyo Japanese, and discusses several implications for the semantic and phonological theories of focus. The intonation of declarative sentences, wh-questions, and yes/no-questions are systematically compared. The results show that the wh-question exhibits an F0-prominence on the wh-phrase, while the yes/no-ques

Pedestrian merging flows on stairs are defined as the confluence of a flow of pedestrians from a stair and pedestrians from each floor of a multi-storey building. This paper introduces a novel simplified mathematical model for the calculation of evacuation times on stairs which takes into account the impact of merging flows. The model allows calculating the impact of merging ratio (people accessin

Dog polymorphonuclear leukocyte cathepsin G was isolated from a granule extract using a two-step procedure including affinity chromatography on aTrasylol-Sepharose gel and ion-exchange chromatography on a CM 52 column. 22 of the first 24 N-terminal amino acids were determined and showed 83% and 71% identity to those of human and rat cathepsin G, respectively. Total amino-acid composition demonstra