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Flipping the stimulus : effects on scanpath coherence?

In experiments investigating dynamic tasks, it is often useful to examine eye movement scan patterns. We can present trials repeatedly and compute within-subjects/conditions similarity in order to distinguish between signal and noise in gaze data. To avoid obvious repetitions of trials, filler trials must be added to the experimental protocol, resulting in long experiments. Alternatively, trials c

Large strain phase-field based multi-material topology optimization

A multi‐material topology optimization scheme is presented. The formulation includes an arbitrary number of phases with different mechanical properties. To ensure that the sum of the volume fractions is unity and in order to avoid negative phase fractions, an obstacle potential function, which introduces infinity penalty for negative densities, is utilized. The problem is formulated for nonlinear

Gender imbalance in a university hierarchy: can stimulus from outside prompt change?

Abstract in UndeterminedThe article draws on the reports by 12 guest professors - all women - who participated in an EU-financed pedagogical project within a Swedish university's postgraduate studies course, the purpose of which was to address equal opportunities in academia. It has been established that women with doctoral degrees are not being absorbed into the research community. The purpose of

Complex selection associated with Hox genes in a natural population of lizards

Hox genes are recognized for their explanatory power of bilateral development. However, relatively little is known about natural variation in, and the evolutionary dynamics of, Hox genes within wild populations. Utilizing a natural population of sand lizards (Lacerta agilis), we screened HoxA13 for genetic variation and an association with incidence of offspring malformations. We found significant

Diffraction-limited storage rings - a window to the science of tomorrow.

This article summarizes the contributions in this special issue on Diffraction-Limited Storage Rings. It analyses the progress in accelerator technology enabling a significant increase in brightness and coherent fraction of the X-ray light provided by storage rings. With MAX IV and Sirius there are two facilities under construction that already exploit these advantages. Several other projects are

Cytokines and growth factors modify the upregulation of contractile endothelin ET(A) and ET(B) receptors in rat cerebral arteries after organ culture.

Aim: Experimental cerebral ischemia and organ culture of cerebral arteries induce an increased endothelin ET(B) receptor-mediated contraction. The aim of the present study was to examine if cytokines and growth factors, known to be activated in ischemia, can influence the expression and function of endothelin receptors after organ culture. Methods: Rat middle cerebral arteries were cultured for 24

MicroRNAs in Bladder Outlet Obstruction: Relationship to Growth and Matrix Remodelling.

The discovery of microRNAs (miRNAs), which are ~22 nucleotide RNAs that inhibit protein synthesis in a sequence-specific manner and are present in a range of species, has born hope of new therapeutic strategies. miRNAs play important roles in development "Development" of what??and disease, but they remain poorly studied in uropathologies beyond cancer. Here, we discuss biological functions of miRN

Supersymmetry: Early Roots That Did Not Grow

This paper is about early roots of supersymmetry, as found in the literature from 1940s and early 1950s. There were models where the power of "partners" in alleviating divergences in quantum field theory was recognized. However, other currently known remarkable features of supersymmetry, such as its role in the extension of the Poincare group, were not known. There were, of course, no supersymmetr

Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients

To validate common low-risk variants predisposing for breast cancer (BC) in a large set of BRCA1/2 negative familial or genetically enriched cases from Germany, we genotyped 1,415 cases and 1,830 healthy women by MALDI-TOF in 105 candidate SNPs. Significantly higher ORs than previously reported for heterozygous unselected cases were found for the minor allele in FGFR2 (OR = 1.43, 95% Cl 1.30-1.59,

Marital status and generalized trust in other people: A population-based study

The association between marital status and generalized trust in other people was investigated. The public health survey in Skane 2008 is a cross-sectional study including 28,198 persons (55% participation rate) aged 18-80 in southern Sweden. Logistic regression models investigated associations between marital status and trust, adjusting for age, country of birth, education, emotional support, inst

Singular-Value Decomposition of Solution Operators to Model Evolution Equations

We consider evolution equations generated by quadratic operators admitting a decomposition in creation-annihilation operators without usual ellipticity-type hypotheses; this class includes hypocoercive model operators. We identify the singular-value decomposition of their solution operators with the evolution generated by an operator of harmonic oscillator type, and in doing so derive exact charac

Measuring overload effects during fatigue crack growth in bainitic steel by synchrotron X-ray diffraction

In this work we present the results of in situ synchrotron X-ray diffraction measurements of fatigue crack-tip strain fields following a 100% overload (OL) under plane strain conditions. The study is made on a bainitic steel with a high toughness and fine microstructure. This allowed a very high (60 mu m) spatial resolution to be achieved so that fine-scale changes occurring around the crack-tip w

Energy exchange and water budget partitioning in a boreal minerogenic mire

This study investigated patterns and controls of the seasonal and inter-annual variations in energy fluxes (i.e., sensible heat, H, and latent heat, lambda E) and partitioning of the water budget (i.e., precipitation, P; evapotranspiration, ET; discharge, Q; and soil water storage, Delta S) over five years (2001-2005) in a boreal oligotrophic fen in northern Sweden based on continuous eddy covaria

Work productivity in a population-based cohort of patients with spondyloarthritis.

Objective. To assess work productivity and associated factors in patients with SpA.Methods. This cross-sectional postal survey included 1773 patients with SpA identified in a regional health care register. Items on presenteeism (reduced productivity at work, 0-100%, 0 = no reduction) were answered by 1447 individuals. Absenteeism was defined as register-based sick leave using data from a national

Long term (13 years) prognosis after primary intracerebral haemorrhage: a prospective population based study of long term mortality, prognostic factors and causes of death.

INTRODUCTION: Many studies have focused on short term mortality after primary intracerebral haemorrhage (ICH) whereas long term prognosis and causes of death have been less studied. We therefore examined these issues in a population based cohort of 1 year ICH survivors. METHODS: ICH patients in a defined Swedish population (1.14 million inhabitants) were prospectively registered during 1996. Patie

Multi-scale characterization of pasta during cooking using microscopy and real-time magnetic resonance imaging

Macroscopic properties of pasta, such as the texture, are formed during cooking by a complex interplay of water and heat with the structuring agents starch and gluten. The impact of the starch-to-gluten ratio on microstructure and water distribution in pasta was analyzed by a multi-scale approach combining magnetic resonance imaging (MRI) and light microscopy. The cooking process and thus the wate

A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons

The molecular motor dynein and its associated regulatory subunit dynactin have been implicated in several neurodegenerative conditions of the basal ganglia, such as Huntington's disease (HD) and Perry syndrome, an atypical Parkinson-like disease. This pathogenic role has been largely postulated from the existence of mutations in the dynactin subunit p150(Glued). However, dynactin is also able to a

A horizontally transferred nuclear gene is associated with microhabitat variation in a natural plant population.

Horizontal gene transfer involves the non-sexual interspecific transmission of genetic material. Even if they are initially functional, horizontally transferred genes are expected to deteriorate into non-expressed pseudogenes, unless they become adaptively relevant in the recipient organism. However, little is known about the distributions of natural transgenes within wild species or the adaptive

Fatty Acid Profiles in Smokers with Chronic Periodontitis

We hypothesized that tobacco smoke induces alterations to the 3-OH fatty acids present in lipid A in a manner consistent with a microflora of reduced inflammatory potential. Whole saliva samples and full-mouth clinical periodontal recordings were obtained from persons with (22 smokers; 15 nonsmokers) and without (14 smokers; 15 non-smokers) chronic periodontitis. Clear differences in the contribut