Ever since Dr. Bolia et al. published their paper of intentional subintimal angioplasty more than 20 years ago it have become a more and more used technique in several centres around the world. Its popularities have gained the last 5 years, following a number of publications from various centres in Europe and the USA. After its initial successes in the femoropopliteal segment, the techniques has b

The Exeter stem and impacted, morselized allograft bone and cement were used in the revisions of 18 consecutive femoral components (17 patients). The primary arthroplasty had been done because of osteoarthritis. All of the femoral components were revised for the first time because of aseptic loosening. The migration pattern of the Exeter stem after revision was studied using roentgen stereophotogr

A brief description of the operational principles of an Electron Beam Ion Trap is given with specific reference to the currently under development/construction Shanghai EBIT. This is followed by an introduction to some of the frontier physics problems of highly charged ions that can be studied with such devices. Also a discussion of the use of EBITs as a powerful tool in hot-plasma diagnostics is

Determination of Local Heat-Transfer Coefficients Around a Circular Cylinder Under an Impinging Air Jet

Background Ex vivo gene therapy and cell replacement in the nervous system may provide therapeutic opportunities for neurodegenerative disorders. The development of optimal gene marking procedures for human neural stem cells (hNSCs) is crucial for the success of these strategies, in order to provide a correct understanding of the biology of transplanted cells. Methods hNSCs were modified to expres

Recent progress on the nature of short-duration gamma-ray bursts has shown that a fraction of them originate in the local Universe. These systems may well be the result of giant flares from soft gamma-repeaters (highly magnetized neutron stars commonly known as magnetars). However, if these neutron stars are formed via the core collapse of massive stars then it would be expected that the bursts sh

Background-The upstream transcription factor 1 (USF1) gene is associated with familial combined hyperlipidemia, the most common genetic dyslipidemia in humans, as well as with various dyslipidemic changes in numerous other studies. Typical of complex disease-associated genes, neither the explicit mutations have been described nor the functional consequences for risk allele carriers been reported a

We present a novel method for investigating subsite-substrate interactions of glycoside hydrolases and the determination of the oligosaccharide cleavage point based on the analysis of the hydrolysis products produced in the presence of (18)O-labelled water. Conventional techniques for such determination of the hydrolysis pattern call for the chemical modification of the substrate, whereas the meth

BACKGROUND: Functional characteristics of the pharynx and upper esophagus, including aspiration episodes, were investigated in 14 awake volunteers during various levels of partial neuromuscular block. Pharyngeal function was evaluated using videoradiography and computerized pharyngeal manometry during contrast bolus swallowing. METHODS: Measurements of pharyngeal constrictor muscle function (contr

The influence of temperature on the growth of the mould Penicillium roqueforti growing on malt extract agar was studied by correlating the produced heat (measured by isothermal calorimetry), ergosterol content (quantified by GC-MS/MS) and biomass of the mould at 10, 15, 20, 25 and 30°C. The results were analysed with a simple metabolic model from which the metabolic efficiency was calculated. The

Iddm14 (formerly Iddm4) is a non-MHC-linked genetic locus associated with autoimmune diabetes. Its effects have been well-documented in BB-derived rats in which diabetes is either induced by immunologic perturbation or occurs spontaneously. The role of Iddm14 in non-BB rat strains is unknown. Our goal was to extend the analysis of Iddm14 in new diabetes-susceptible strains and to identify candidat

Twenty-six fully sequenced archaeal genomes were searched for genes coding for putative deoxyribonucleoside kinases (dNKs). We identified only 5 human-like thymidine kinase 1 genes (TK1s) and none for non-TK1 kinases. Four TK1s were identified in the Euryarchaea and one was found in the Crenarchaea, while none was found in Nanoarchaeum. The identified TK1s have high identity to Gram-positive bacte

A study of past lake-level changes in Lake Xinias covering the last 40 000 years was presented in an earlier paper. In that paper.. changes during the Holocene were only briefly dealt with. because of poor sedimentary representation. In this paper a Supplementary transect of cores is described, in which Holocene lake-level changes are better recorded. The correlation of the cores was based on poll

The viscoelastic properties of several multicomponent materials (including both particulate multipolymeric materials and multilayer polymer blends) were investigated in relation to their microstructures and phase-property dependencies. Theoretical considerations based on mechanical modeling were used to explore the origin of additional mechanical transitions in experimental viscoelastic spectra. T

Although glycogen storage disease type 0 (GSD0) is included in the differential diagnosis of ketotic hypoglycemia, it usually is not considered in the evaluation of glucosuria or hyperglycemia. We describe two children with GSD0, confirmed by mutation analysis, who had glucosuria and hyperglycemia. Because of the variable presentation of this disorder and previous dependence on liver biopsy to con