Fusobacterium necrophorum is a well-known cause of Lemirre's disease and accumulating evidence support its pathogenic role in peritonsillar abscess while its role in recurrent and chronic tonsillitis is uncertain. The objective of this study was to assess the prevalence of oropharyngeal colonisation with F. necrophorum and Beta-haemolytic streptococci in a cohort of patients scheduled for tonsille

Retinitis pigmentosa (RP) defines a group of inherited degenerative retinal diseases causing progressive loss of photoreceptors. To this day, RP is still untreatable and rational treatment development will require a thorough understanding of the underlying cell death mechanisms. Methylation of the DNA base cytosine by DNA methyltransferases (DNMTs) is an important epigenetic factor regulating gene

Isotropic chiral media can be modelled in several ways. We show that when realizing such a medium from spiral inclusions with real permittivities and permeabilities in a periodic structure, a modified Drude–Born–Fedorov model is obtained. This model equals the original Born model for small wave vectors, but the strength of the chirality depends on the propagation direction. The effective parameter

We have implemented intraprocedural control-flow and data-flow analysis of Java source code in a declarative manner, using reference attribute grammars augmented with circular attributes and collection attributes. Our implementation is built on top of the JastAdd Extensible Java Compiler and we have run the analyses on medium-sized Java programs. We show how the analyses can be built using sma

To compare 2D transperineal ultrasound assessment of cervical dilatation with vaginal examination and to investigate intra-observer variability of the ultrasound method.

Background: FUS, EWS and TAF15 are structurally similar multifunctional proteins that were first discovered upon characterization of fusion oncogenes in human sarcomas and leukemias. The proteins belong to the FET ( previously TET) family of RNA-binding proteins and are implicated in central cellular processes such as regulation of gene expression, maintenance of genomic integrity and mRNA/microRN

Chromosomal instability is a known hallmark of many cancers. DNA polymerases represent a group of enzymes that are involved in the mechanism of chromosomal instability as they have a central function in DNA metabolism. We hypothesized that genetic variation in the polymerase genes may affect gene expression or protein configuration and by that cancer risk and clinical outcome. We selected four gen

We have characterized the lipid chain freezing in dilute aqueous vesicle dispersions of the cationic lipid dioctadecyldimethylammonium bromide (DODAB) using wide and small angle X-ray scattering, solid state NMR, DSC, turbidity and density measurements. The lipids freeze in two steps. Above 40 degrees C the chains are fluid and the lipids are in a so-called liquid-crystalline state. When cooling b

The large bloom-forming flagellate Gonyostomum semen has been hypothesized to be inedible to naturally occurring zooplankton due to its large cell size and ejection of long slimy threads (trichocysts) induced by physical stimulation. In a grazing experiment using radiolabelled algae and zooplankton collected from lakes with recurring blooms of G. semen and lakes that rarely experience blooms, we f

Background: Calreticulin (CRT) is a ubiquitous ER protein involved in multiple cellular processes in animals, such as protein folding and calcium homeostasis. Like in animals, plants have evolved divergent CRTs, but their physiological functions are less understood. Arabidopsis contains three CRT proteins, where the two CRTs AtCRT1a and CRT1b represent one subgroup, and AtCRT3 a divergent member.

To address the problems of climate change and energy security, Chinese government strived to develop renewable power as an important alternative of conventional electricity. In this paper, the learning curve model is employed to describe the decreasing unit investment cost due to accumulated installed capacity; the technology diffusion model is used to analyze the potential of renewable power. Com

The production of deuterons and anti-deuterons in the transverse momentum range 1.1

Treatment of sludge with enzymes has previously been shown to efficiently release organic matter. However, the added enzymes were partially adsorbed to, entrapped by or bound to the sludge structure. Simultaneous decrease of enzymes activities was observed. Reduced adsorption and more effective, lower, enzyme dose was achieved in sludge pre-treated with three cation-binding agents. The enzymatic s

We examine how the generation and propagation of high-order harmonics in a partly ionized gas medium affect their strength and synchronization. The temporal properties of the resulting attosecond pulses generated in long gas targets can be significantly influenced by macroscopic effects, in particular by the intensity in the medium and the degree of ionization which control the dispersion. Under s

Caldicellulosiruptor owensensis strain OLT (DSM 13100) is an obligately anaerobic, extreme thermophilic bacterium that is capable of utilizing a broad range of carbohydrates and producing H2 as a metabolic by-product. The performance of C. owensensis on glucose and xylose was analyzed in lab-scale bioreactors to assess its potential use in biohydrogen production. Acetate, H2, and CO2 were the main

The World Health Organization has a standardized tool to assess surgical capacity in low- and middle-income countries (LMICs), but it is often resource- and time-intensive. There currently exists no simple, evidence-based measure of surgical capacity in these settings. The proportion of cesarean deliveries in regard to the total operations (C/O ratio) has been suggested as a way to assess quickly

Popular Abstract in Swedish Reumatoid artrit (RA) även kallat ledgångsreumatism, är en ledsjukdom som innebär inflammationer i kroppens leder. Sjukdomens symptom är smärta, trötthet, nedsatt fysisk kapacitet med svullna, ömma leder. Kvinnor drabbas i större utsträckning av ledgångsreumatism än män. Sjukdomen är kronisk och behandlas med antireumatiska läkemedel samt kompletterande teambaserad behaThe overall aim of this thesis was to study how persons experience the influence of Rheumatoid Arthritis (RA) on their sexual health and their experiences of communication about sexual health, in order to improve physiotherapy within the field of rheumatology. Sexual health is an integrated part of life, and persons with Rheumatoid Arthritis, RA, often experience a decreased sexual health, which c

The three-year research project funded by MSB applies design science, in combination with traditional scientific investigation, to develop a method to guide the planning phase of capacity development projects for disaster risk reduction and climate change adaptation. The method facilitates local participation and ownership as it builds on the strengths of the Logical Framework Approach (LFA), whil