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Electrical wiring of live, metabolically enhanced Bacillus subtilis cells with flexible osmium-redox polymers.

The present study explores genetic engineering of the respiratory chain and the application of two different flexible osmium redox polymers to achieve efficient electric communication between the gram-positive organism Bacillus subtilis and an electrode. Poly(1-vinylimidazole)(12)-[Os-(4,4'-dimethyl-2,2'-bipyridyl)(2)Cl(2)](+/2+) (osmium redox polymer I) and poly(vinylpyridine)-[Os-(N,N'-methylate

PON-P2: Prediction Method for Fast and Reliable Identification of Harmful Variants.

More reliable and faster prediction methods are needed to interpret enormous amounts of data generated by sequencing and genome projects. We have developed a new computational tool, PON-P2, for classification of amino acid substitutions in human proteins. The method is a machine learning-based classifier and groups the variants into pathogenic, neutral and unknown classes, on the basis of random f

A Novel Method to Determine Magnetic Fields in Low-density Plasma Facilitated Through Accidental Degeneracy of Quantum States in Fe9+

We propose a new method to determine magnetic fields, by using the magnetic-field-induced electric dipole transition 3p(4) 3d D-4(7/2) -> 3p(5) P-3/2 in Fe9+ ions. This ion has a high abundance in astrophysical plasma and is therefore well suited for direct measurements of even rather weak fields in, e.g., solar flares. This transition is induced by an external magnetic field and its rate is propo

Biocatalytic potential of vanillin aminotransferase from Capsicum chinense.

The conversion of vanillin to vanillylamine is a key step in the biosynthetic route towards capsaicinoids in pungent cultivars of Capsicum sp. The reaction has previously been annotated to be catalysed by PAMT (putative aminotransferase; [GenBank: AAC78480.1, Swiss-Prot: O82521]), however, the enzyme has previously not been biochemically characterised in vitro.

In-vivo dark-field and phase-contrast x-ray imaging.

Novel radiography approaches based on the wave nature of x-rays when propagating through matter have a great potential for improved future x-ray diagnostics in the clinics. Here, we present a significant milestone in this imaging method: in-vivo multi-contrast x-ray imaging of a mouse using a compact scanner. Of particular interest is the enhanced contrast in regions related to the respiratory sys

[(BINAP)Re(O)Cl-3] as an efficient catalyst for olefination of chiral alpha-substituted aliphatic aldehydes

A convenient one-pot preparation of [(BINAP) Re(O)Cl-3] (6) is described. This complex was demonstrated to be an efficient catalyst for the olefination of aldehydes by reaction with alpha-diazo esters, with essentially quantitative yields and up to 98:2 geometric selectivity. The potential for using enantiopure [(BINAP)Re(O)Cl-3] (6) to promote an asymmetric kinetic resolution of racemic alpha-ste

Crystal Phase Engineering in Single InAs Nanowires.

Achieving phase purity and control in III-V nanowires is a necessity for future nanowire-based device applications. Many works have focused on cleaning specific crystal phases of defects such as twin planes and stacking faults, using parameters such as diameter, temperature, and impurity incorporation. Here we demonstrate an improved method for crystal phase control, where crystal structure variat

En lundensisk filmpionjär

Om Karl Oskar Krantz (1867-1933), grundare av Lunds andra permanenta biograf och stadens första filmproducent (bl a av de första karnevalsfilmerna).

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

Embryonic stem cells (ESCs) represent a promising source of midbrain dopaminergic (DA) neurons for applications in Parkinson disease. However, ESC-based transplantation paradigms carry a risk of introducing inappropriate or tumorigenic cells. Cell purification before transplantation may alleviate these concerns and enable identification of the specific DA neuron stage most suitable for cell therap

Practical Applications of Asymmetrical Flow Field-Flow Fractionation (AF4): A Review

Characterization of macromolecules and colloids is an area of considerable interest. Asymmetrical flow field-flow fractionation (AF4) has become a well-established method, but many potential users possess limited knowledge of its capabilities, or how it can provide additional information or serve as validation to the traditional analytical techniques. This review article highlights several practic

Effects of Sensory Feedback in Intra-Oral Target Selection Tasks with the Tongue

Purpose: To investigate the effects of visual and tactile intra-oral sensor-position feedback for target selection tasks with the tip of the tongue. Method: Target selection tasks were performed using an inductive tongue-computer interface (ITCI). Visual feedback was established by highlighting the area on a visual display corresponding to the activated intra-oral target. Tactile feedback was esta

Feeding the Needy Student: Auto-Ethnographic Reflections from South India

Towns and cities have always been sites of attraction not only as centers of trade and commerce, seats of administration and power centers but also providing facilities for health and education. This is especially true of post-colonial nations such as India, marking differences between rural and urban areas in many significant ways. The late colonial and early post-colonial periods experienced wid

Indication for pharmacological treatment is often lacking: a cross-sectional study on the quality of drug therapy among the elderly.

Although the elderly have a substantially higher drug use than younger patients, even after adjustment for multimorbidity, there is limited knowledge about the elderly's indication for treatment. It is essential for elderly patients to have a well-planned drug therapy. The first step towards a correct and safe drug therapy is to ensure that the patient's drugs have an indication, i.e. correct diag

Etnicitet i ungdomsvården. Yrkesverksammas och ungdomarnas muntliga framställningar

I denna studie analyseras muntliga etnicitetsgestaltningar hos olika aktörer i ungdomsvården. Undersökningen uppmärksammar etniciteten när den uttrycks verbalt och icke-verbalt, hur den uttrycks samt i vilka situationer kategoriseringar synliggörs implicit eller explicit. Studiens syfte är: att analysera när och hur etnicitet aktualiseras genom kategoriseringar i ungdomsvården, att uppmärksamma hThe aim of this study is to analyze when and how ethnicity is actualised through categorisations in Swedish youth-care, to attract attention to how these categorisations are indicated and point out how the narrators own ethnic identity is shaped and upheld through different markings. The report is based on 109 interviews conducted with different actors in the youth-care and my field-notes made in