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The unintended consequences of modernity : Pollution and its effect on reproductive, maternal and fetal health

Over the past 50 years there has been an unprecedented increase in pollution globally. Population growth and higher standards of living have resulted in increases in global consumption facilitated by industrialisation and globalisation of goods and services thus resulting in the release of environmental pollutants on a mass scale. This article analyses the effects and consequences of pollution on

Preclinical Protein Signatures of Crohn's Disease and Ulcerative Colitis : A Nested Case-Control Study Within Large Population-Based Cohorts

Background & Aims: Biomarkers are needed to identify individuals at elevated risk of inflammatory bowel disease. This study aimed to identify protein signatures predictive of inflammatory bowel disease. Methods: Using large population-based cohorts (n ≥180,000), blood samples were obtained from individuals who later in life were diagnosed with inflammatory bowel disease and compared with age a

Two photoacoustic spectral coloring compensation techniques adapted to the context of human in-vivo oxygenation measurements

Photoacoustic imaging can potentially map oxygen saturation (sO2) non-invasively. However, in-vivo human application is challenging due to spectral coloring, which causes a wavelength-dependent fluence attenuation and uncertainty in the estimation of chromophore concentrations deep in tissue. This study compares the performances of two previously proposed methods for spectral coloring compensation

Revealing the 1,4-diethynylbenzene SERS activity and docking studies by DFT

Surface-enhanced Raman scattering (SERS) technology can detect molecular information; Because of its high sensitivity, it is widely used in chemical analysis. In this study discussed the experimental detection of 1,4-diethynylbenzene molecule based on SERS technology. The SERS spectra of 1,4-diethynylbenzene molecule were calculated by Density Functional Theory (DFT) simulation, and the results sh

Long-range transport influence on wintertime submicron aerosol chemical composition from simultaneous measurements in Lithuania and Southern Sweden

Due to the large extent of seawater surface over the globe, aerosol particles spend significant time being transported over this type of surface. Therefore, global aerosol circulation is largely impacted by the processes particles undergo during long-range transport overseas. In this study, we investigated submicron aerosol (PM1) chemical composition changes during long-range transport events over

On the reduction of imaging time-points for dosimetry in radionuclide therapy

Background: The aim was to develop a theoretical framework for how errors in estimated activities propagate to a dispersion in time-integrated activity in radionuclide-therapy dosimetry and how this affects the comparison of radionuclide-therapy dosimetry schemes. Methods: Formulae for the variance of relative errors of estimated time-integrated activities and relative differences in time-integrat

White Book on Inclusive Science Education : Towards promoting an inclusive approach in science education

This document has been developed to provide practical resources to policymakers, institutional representatives, and educators, by offering a diverse range of examples and recommendations at various levels to support the implementation and enhancement of ISE.The White Book is founded on the theoretical framework of ISE developed throughout the Communities or Sciences (C4S) Towards Promoting an Incl

TREM2 risk variants and associated endophenotypes in alzheimer’s disease

Background: Rare variants of the triggering receptor expressed on myeloid cell 2 (TREM2) gene are strong risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown what the effect of TREM2 variants is on the AD phenotype. Methods: Here we studied a full range of clinical and biomarker measures in a large cohort of TREM2 variant carr

Molecular mechanisms underlying thrombosis in systemic lupus erythematosus – A Systematic review

Patients with systemic lupus erythematosus (SLE) face an approximately 30 % risk of thrombosis post-diagnosis. However, there remains significant knowledge gaps regarding causative mechanisms, and there is a lack of specific antithrombotic guidelines. This systematic review aims to examine the existing literature regarding the mechanisms contributing to thrombosis risk in SLE, focusing on five pre

Early life factors and variation in adult kidney function in the Swedish LifeGene cohort

Intrauterine fetal programming determines cardiorenal interaction later in life. We hypothesize that early life factors affect adult glomerular filtration rate and mean arterial pressure (MAP) directly or by interacting with postnatal growth trajectories. The population-based LifeGene study (Sweden) randomly recruited individuals aged 18 to 43 years (n = 12 167). They filled in a web-questionnaire

Resolving active species during the carbon monoxide oxidation over Pt(111) on the microsecond timescale

Catalytic studies traditionally rely on steady-state conditions resulting in time-averaged datasets that do not differentiate between active and spectator species. This limitation can cause misinterpretations of catalytic function, as the signal of short-lived intermediates responsible for producing desired reaction products is often masked by more intense spectator species. Time-resolved ambient

Anställningsskyddets framväxt och utveckling: Ett historiskt perspektiv - En analys av anställningsskyddet från dåtid till nutid

Denna uppsats analyserar det svenska anställningsskyddet ur ett historiskt perspektiv från 1833 års legostadga till dagens arbetsrättslagstiftning (Prop. 2021/22:176). Uppsatsens huvudfokus ligger på kraven för att en uppsägning ska vara giltig (7 § LAS) och turordningsbestämmelser vid arbetsbrist (22 § LAS). Anställningsskyddet har genom historien gått i vågor mellan starkt skydd och svagt skyd

VAT Treatment of Vouchers - The Voucher Directive and its application to city cards and VAT Special Schemes – Do the rules provide an answer to their VAT consequences?

This thesis explores the Value Added Tax (VAT) treatment of vouchers within the framework of the EU’s Voucher Directive, with a particular focus on its application to discount vouchers, city cards, and VAT special schemes. The Voucher Directive has been implemented to harmonize and clarify the VAT treatment of vouchers across Member States including distinctions between single-purpose and mult

"I don't have to suffer just because I'm an activist": The role of humour as an adaptive coping strategy in managing eco-anxiety of climate activists

The concept of ‘eco-anxiety’ has increasingly gained traction both in media and academia, with climate activists hypothesised as prone to experiencing it. However, humour has for long been a crucial aspect of social movements, and it holds strong potential in adaptively coping with stressors. Therefore, this thesis aims to describe climate activists’ emotional experiences characterised as eco-anxi

Influence of Horizontal Projections on Thermal Exposure to Façades in Fire Scenarios

The increasing frequency of facade fires, often exacerbated by combustible cladding systems, has emphasized the need for passive fire protection strategies. Among these, horizontal projections—such as balconies, canopies, and deflectors—have emerged as potential fire safety elements. This thesis investigates the influence of horizontal projections on thermal exposure and lateral flame spread acros

Vem talar för arbetarklassen? En kritisk diskursanalys av förändringar i användningen av klassbegreppet i svenska slutdebatter

Den svenska partipolitiken kännetecknades länge av en tydlig klassdiskurs, och ansågs vara undantaget för nedgången i den klassbaserade röstningen. Under de senaste decennierna har däremot även Sverige genomgått förändringar i den klassbaserade röstningen där arbetarklassens väljare alltmer förflyttats från socialdemokratin till högernationalistiska partier. Följande undersökning avser därför att

Points in Contrasts

A fluid and undefined existence that tears in all directions, a total chaos swirling like a storm that diminishes the recognisable, creating confusion and disorientation. The question is whether to shape something in the outer, or whether something in the outer should be allowed to shape the inner: to let oneself be shaped by what is external, or to let what is external shape the internal. The two

Relativistic Calculations for Trapped Ions

We present recent results in the field of total binding energy calculations, Landщ factors, quantum electrodynamics corrections and lifetime that are of interest for ion traps and ion sources. We describe in detail MCDF and RMBPT calculation of ionic binding energies, which are needed for the determination of atomic masses from highly charged ion measurements. We also show new results concerning L