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Viral protein X (Vpx) is a unique accessory protein encoded by the genome of the human immunodeficiency virus type 2 (HIV-2) and lineages of the simian immunodeficiency virus of sooty mangabeys. So far, counteracting the cellular restriction factor SAMHD1 and mediating the efficient translocation of viral pre-integration complex have been recognized as key functions of Vpx; however, a thorough exp
Safety in general and fire safety in particular are key concerns in neutron-based research facilities, and the choice of the material that is used to stop neutron radiation is critical in this respect. Borated paraffin has been used at existing research facilities and could potentially be used at new facilities. However, a literature search resulted in very little information about the fire proper
Welfare technology (WT) use is increasingly advocated to facilitate aging in place. However, it remains unclear how older adults and homecare staff perceive these digital technologies in practice. This qualitative study investigated the ways in which current WT either facilitated or fell short in supporting older adults in their daily lives and homecare staff at work. Four key themes were develope
PURPOSE Remote symptom monitoring shows promise in promoting postdischarge contact between patients and clinicians. Unique strategies may be needed to tailor reach and engagement to specific patient populations. We aimed to assess implementation and effectiveness outcomes of a patient-reported symptom assessment tool (Recovery Tracker [RT]) after major urologic operations.MATERIALS AND METHODS Pat
Quantifications of phytoplankton biomass and species composition are crucial for monitoring biodiversity and population dynamics in aquatic environments, and both direct microscopic counts and fluorescence-based methods have been widely used for monitoring. Recent advancements in DNA metabarcoding offer an alternative way of easily assessing diversity and species composition. However, a comprehens
Interconnected societal challenges such as climate change, biodiversity loss and food security demand immediate and coordinated action across local to global scales, guided by coherent policies and management mechanisms. Reflecting on the critical need to address societal challenges, Nature-based Solutions in marine and coastal environments, known as blue NBS, have emerged as an important part of
We investigate the impact of employment protection regulation on firms’ reluctance to apply for bank finance (loans and overdrafts). Our findings reveal that longer notice periods reduce the likelihood that firms are discouraged from applying for bank finance in the case of blue-collar workers, but they increase it in the case of white-collar workers. Our interpretation is that, in the case of blu
The maintenance of variation (i.e., different phenotypes) for heritable traits that are under selection, despite expectations of selection eroding variation and favouring only the fittest phenotype, represents an evolutionary paradox. Here, we studied variation in life-history traits in five populations of colour polymorphic tawny owls (Strix aluco) across Europe that have been individually studie
Globally, thousands of apheresis procedures are performed on a daily basis. Besides, these are relatively short and easy-to-perform preparative procedures in healthy volunteers like plasmapheresis or platelet donation; other procedures like hematopoietic cell donation are more complicated and of longer duration. Therapeutic apheresis is somewhat more challenging, especially in critically ill patie
We study the Higgs boson decay into dark matter (DM) in the framework of freeze-in at stronger coupling. Even though the Higgs-DM coupling is significant, up to order one, DM does not thermalize due to the Boltzmann suppression of its production at low temperatures. We find that this mechanism leads to observable Higgs decay into invisible final states with the branching fraction of 10% and below,
High-speed vertical In–Ga–As nanowire MOS field-effect transistor (MOSFET) measurements were analyzed through parametric layout models. Measurements from small and large transistors were used to fit dependencies on the number of gate fingers and the number of wires per finger. Extrapolations via intrinsic and parasitic elements reveal the optimal layout for peak frequency performance. To achieve a
In Sweden, the national security objective to establish a total defence, which has been pending since the end of the Cold War, has been reintroduced. This has increasingly shifted the attention from civil crisis management to military defence, with subsequent increased resources for defence mobilization. A key threat representation in the current Swedish security narrative is the grey zone, which
The “nutmeg lung pattern” on fetal magnetic resonance imaging (MRI) indicates pulmonary lymphangiectasia. This is associated with adverse outcomes, particularly in fetuses with congenital heart defects and impaired pulmonary venous return. Whereas lymphedema is common in fetuses with Turner syndrome, pulmonary lymphangiectasia is not. A 26-year-old woman presented with a fetus with hypoplastic lef
Developmental language disorder (DLD) affects around 7.5 percent of students. The risks of DLD for reduced educational progress are well documented but teachers often do not feel adequately prepared to support this student group. This study aims to broaden the understanding of teachers’ experiences of working with students with DLD in Swedish mainstream secondary schools. Five focus group intervie
In this paper, we propose an approach that combines Vision Language Models (VLMs) and Behavior Trees (BTs) to address failures in robotics. Current robotic systems can handle known failures with pre-existing recovery strategies, but they are often ill-equipped to manage unknown failures or anomalies. We introduce VLMs as a monitoring tool to detect and identify failures during task execution. Addi
Deposition of phosphorus (P) is important for the nutrient supply to forests and open land but also contributes to the eutrophication of surface waters. Deposition to open land can be measured as bulk deposition while deposition to forests cannot be measured directly, due to internal circulation of P within forest canopies. This study aimed to quantify the total deposition of P to open land and fo
This chapter by Emily Silva and Oksana Mont examines the role of libraries of things (LoTs) in reducing consumption through socially sustainable practices. It highlights LoTs' potential to address sustainability and service challenges in circular and sharing business models. The study, based on data from 90 LoTs across North America, Europe and Australia, explores motivations and business model co
We evaluated the association between cardiopulmonary bypass (CPB) time during surgery for acute type A aortic dissection (ATAAD) and mid-term survival. Data of 1122 patients who underwent surgery for ATAAD in eight Nordic centers from January 2005 to December 2014 were retrospectively analyzed. An adjusted logistic regression analysis was performed to investigate the association of incremental 30
The journal Högre utbildning (HU) celebrated its 10th anniversary in 2021. To mark the occasion, the editorial team conducted a review of contributions published between 2011 and 2021. This article presents the results of the review along with reflections on HU’s mission to promote the development of knowledge about higher education within a Swedish and Nordic context. Since its inception in 2011,
In recent years, extreme flow events in rivers have become more frequent and caused numerous bridge failures worldwide. Such events increase headwater levels in the rivers that may cause water to flow over the bridge deck, referred to as bridge overtopping. This is one of the primary factors affecting bridge functionality, possibly leading to failure. In general, bridges are designed and construct
