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The art(s) of getting lost : Halting places for culturally responsive research methods

This chapter revisits the ideas of radical empiricism and sensuous scholarship, embedded in current music education research. Focusing on the development of methodological implications of cultural responsiveness and arts-based research methods, the chapter argues for epistemic openness. The discussion is located within the author’s own experiences of course development for Swedish music teacher st

Updated European Association of Urology Guidelines on Renal Cell Carcinoma : Nivolumab plus Cabozantinib Joins Immune Checkpoint Inhibition Combination Therapies for Treatment-naïve Metastatic Clear-Cell Renal Cell Carcinoma

Longer follow-up and new trial data from phase 3 randomised controlled trials investigating immune checkpoint blockade (PD-1 or its ligand PD-L1) in advanced clear-cell renal cell carcinoma (RCC) have recently become available. The CheckMate 9ER trial demonstrated an improved progression-free survival (PFS) and overall survival (OS) benefit for the combination of cabozantinib plus nivolumab. A Key

The vitamin D receptor (VDR) start codon polymorphism in primary hyperparathyroidism and parathyroid VDR messenger ribonucleic acid levels

Vitamin D regulates parathyroid cell proliferation and secretion of PTH. Increased prevalence of the polymorphic vitamin D receptor (VDR) alleles b, a, and T has been reported in sporadic primary hyperparathyroidism (PHPT), suggesting that these genetic variants may predispose to the disease. Recently, another polymorphism in the VDR gene was related to bone mineral density, and this VDR-FokI poly

Introduction

As the nineteenth century turned to the twentieth, the relation between the law and the Christian church became increasingly challenged in Europe. Social claims from political forces and increasingly strong labor unions formed the introduction to the modern social welfare state. In the increasingly secularized Nordic societies, Christian philanthropy was replaced by social legal reforms in the ear

Christian legal historian and intermediary of Henric Schartau’s religious heritage : Carl Johan Schlyter (1795-1888)

Carl Johan Schlyter was the first modern Swedish legal historian and served as a professor of legal history at Lund University from 1840 to 1876. Schlyter introduced Savigny’s historical school to Sweden, but his great scholarly contribution was his edition of the Swedish medieval laws, published in thirteen volumes from 1827 to 1877. He was also a deeply religious Christian. Schlyter and his teac

Molecular diagnostics of salmonella and campylobacter in human/animal fecal samples remain feasible after long-term sample storage without specific requirements

Rapid advances in the development of sequencing technologies, numbers of commercial providers and diminishing costs have made DNA-based identification and diagnostics increasingly accessible to doctors and laboratories, eliminating the need for local investments in expensive technology and training or hiring of skilled technicians. However, reliable and comparable molecular analyses of bacteria in

Tracking Magmatic Hydrogen Sulfur Circulations Using Electrical Impedance : Complex Electrical Properties of Core Samples at the Krafla Volcano, Iceland

Interaction of H2S escaping from magma and basaltic rocks leads to pyrite mineralization, witnessing active hydrothermal circulation. We study the possibility to track this process using geoelectrical methods. Complex conductivity spectra of 30 core samples from the Krafla volcano, Iceland, measured in the laboratory, indicate that pyrite can be discriminated from other minerals present in volcani

Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions

Aims/hypothesis: Sleep, diet and exercise are fundamental to metabolic homeostasis. In this secondary analysis of a repeated measures, nutritional intervention study, we tested whether an individual’s sleep quality, duration and timing impact glycaemic response to a breakfast meal the following morning. Methods: Healthy adults’ data (N = 953 [41% twins]) were analysed from the PREDICT dietary inte

Incidence and Predictors of Heart Failure in Patients With Atrial Fibrillation

Background: Heart failure (HF) is a frequent cause of hospitalization and death in patients with atrial fibrillation (AF). Identifying AF patients at risk of HF hospitalization could help select individuals for intensive follow-up and treatment. Methods: We pooled data from 3 randomized trials (ACTIVE-A, RE-LY, AVERROES) of AF patients, for derivation and internal validation of a risk score for fi

A distortional hardening model for finite plasticity

Plastic anisotropy may strongly affect the stress and strain response in metals subjected to multiaxial cyclic loading. This anisotropy evolves due to various microstructural features. We first use simple models to study how such features result in evolving plastic anisotropy. A subsequent analysis of existing distortional hardening models highlights the difference between stress- and strain-drive

Early Cambrian brachiopod-dominated shell concentrations from North-East Greenland : Environmental and taphonomic implications

The occurrence of a series of thin but persistent early Cambrian (Cambrian Age 4) brachiopod shell concentrations extending along a transect of some 150 km in NE Greenland, indicates the ability of the group to form widespread, skeletal pavements very early in the history of the phylum, its gregarious behaviour and ability to harness available nutrients. These extensive shell pavements within the

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis

Iron deposition is present in main lesion areas in the brains of patients with Parkinson’s disease (PD) and an abnormal iron content may be associated with dopaminergic neuronal cytotoxicity and degeneration in the substantia nigra of the midbrain. However, the cause of iron deposition and its role in the pathological process of PD are unclear. In the present study, we investigated the effects of

The challenges of the expanded availability of genomic information : an agenda-setting paper

Rapid advances in microarray and sequencing technologies are making genotyping and genome sequencing more affordable and readily available. There is an expectation that genomic sequencing technologies improve personalized diagnosis and personalized drug therapy. Concurrently, provision of direct-to-consumer genetic testing by commercial providers has enabled individuals' direct access to their gen