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Drug-related problems in the elderly - Interventions to improve the quality of pharmacotherapy

Popular Abstract in Swedish Läkemedelsrelaterade problem hos äldre - Interventioner för att förbättra läkemedelsbehandlingen Läkare inom primärvården står för en stor del av den totala läkemedelsförskrivningen i Sverige och är en viktig målgrupp för läkemedelsindustrins information. Det har i flera uppmärksammade studier från Socialstyrelsen uppmärksammats att läkemedelsbehandlingen för patientIntroduction: Elderly people, in particular those residing in nursing homes, often use many drugs. In general elderly patients are at greater risk of experiencing drug-related problems (DRP), as they have multiple diseases, are using many drugs and have changed physiological status. Objectives: To describe the frequency of potential drug-related problems in the elderly and to evaluate different k

Study of inclusive J/psi production in two-photon collisions at LEP II with the DELPHI detector

Inclusive J/psi production in photon-photon collisions has been observed at LEP II beam energies. A clear signal from the reaction gammagamma --> J/psi + X is seen. The number of observed N(J/psi --> mu(+)mu(-)) events is 36+/-7 for an integrated luminosity of 617 pb(-1), yielding a cross-section of sigma(J/psi + X) = 45+/-9(stat) +/- 17(syst) pb. Based on a study of the event shapes of different

Gas Diffusion Through Sheets of Fibrous Porous Media

Using a cell model to describe a fibrous porous medium theoretical expressions ale deduced relating effective gas diffusivity to the volume fraction of the fibres. Cylindrical as well as band-shaped fibres are studied. The new models, which are based on solutions to the diffusion equation, agree well with existing correlations. The models are compared with experimental data for water vapour diffus

Ecological diversification in habitat use in subtidal triplefin fishes (Tripterygiidae)

Recent work has shown that habitat specialisation can lead to diversification in lacustrine and marine fish species. Here we investigate specialisation in the New Zealand triplefin fish fauna (Tripterygiidae), which has the greatest diversity and disparity of triplefin species in the world with 26 endemic species. Most species are sympatric throughout coastal New Zealand, showing no obvious latitu

Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine

OBJECTIVES: To ascertain whether patients with Crohn's disease treated with azathioprine maintained bone mineral mass better than patients treated with steroids alone. DESIGN: Retrospective study. SETTING: University Hospital of Malmo, Sweden. SUBJECTS: A total of 59 patients with ileocolonic, ileocaecal or colonic Crohn's disease. METHODS: Bone mass was assessed by dual photon X-ray absorptiometr

Multiple Sclerosis: Studies of the Interferon system and search for infectious agents

Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. Interferons (IFNs) are naturally occurring proteins known to have antiviral, antiproliferative and immunoregulatory eff

New algorithms for prediction of wind effects on cold protective clothing

The European Pre-Standard for protective clothing against cold ENV 342:1998 suggests that the testing of thermal insulation should be made on a moving thermal manikin. In this way the value can be used to match requirements specified by the IREQ-method or as realistic input for prediction of thermal stress in other standards. It is known from prior work that insulation values measured with human s

The effect of asset visibility on managing returnable transport items

Purpose – The purpose of this paper is to propose a framework of the potential benefits of asset visibility in the context of returnable transport items (RTI), and uses the framework to examine the effect of asset visibility on the management of RTI systems. Design/methodology/approach – A combined case study and simulation approach was used. A case study was performed to identify and understand

Rosiglitazone and carotid IMT progression rate in a mixed cohort of patients with type 2 diabetes and the insulin resistance syndrome: main results from the Rosiglitazone Atherosclerosis Study.

Objective. Insulin resistance is associated with progression of atherosclerosis. We assessed the effect of 12 months of treatment with rosiglitazone (RSG) on the progression of carotid intima-media thickness (IMT) in people with type 2 diabetes mellitus (T2DM) or the insulin resistance syndrome (IRS). Design. Randomized, double-blind, placebo-controlled trial. Setting. Malmo University Hospital, M

The Heck reaction under ball-milling conditions

The synthesis of unsaturated unnatural amino acids according to the Heck-Jeffery protocol using a ball-milling procedure is presented. NOE data recorded on the products confirm that the Z-isomer is formed. This type of mechano-chemistry provides an efficient, "solvent free" and reliable method for the synthesis of substituted dehydroalanines. These conditions provide patterns of reactivity complem

Notes on the Cretan mistletoe, Viscum album subsp creticum subsp nova (Loranthaceae/Viscaceae)

Viscum album subsp. creticum, known from two mountain areas of E. Crete, is described as new to science. It combines features of the two presently accepted conifer mistletoes, resembling the fir parasite, subsp. abietis, in gross morphology but genetically (by nrDNA ITS sequence data) close to the pine parasite, subsp. austriacum, while differing from either in hypocotyl shape and nucleotide seque