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FDG PET studies during treatment: Prediction of therapy outcome in head and neck squamous cell carcinoma.

BACKGROUND: Positron emission tomography (PET) provides metabolic information of tissues in vivo. The purpose of this study was to assess the value of PET with 2-[(18) F] fluoro-2-deoxy-D-glucose (FDG) in prediction of therapy outcome (tumor response, survival, and locoregional control) in locally advanced HNSCC. METHODS: Between 1993 and 1999 47 patients underwent PET before (PET(1)) and after (P

Lymphedema - A comprehensive review

Background: Lymphedema is a chronic, debilitating condition that has traditionally been seen as refractory or incurable. Recent years have brought new advances in the study of lymphedema pathophysiology. as well as diagnostic and therapeutic tools that are changing this perspective. Objective: To provide a systematic approach to evaluating and managing patients with lymphedema. Methods: We perform

A Wiener Tauberian Theorem for weighted convolution algebras of zonal functions on the automorphism group of the unit disc

Our main result gives necessary and sufficient conditions, in terms of Fourier transforms, for an ideal in the algebra L-1(G parallel to K, omega), the convolution algebra of zonal functions on the automorphism group on the unit disc which are integrable with respect to the weight; function omega, to be dense in the algebra, or to have as closure an ideal of functions whose set of common zeros of

Generation of MeV electrons and positrons with femtosecond pulses from a table-top laser system

In experiments, the feasibility was demonstrated of generating multi-MeV electrons in a form of a collimated beam utilizing a table-top laser system delivering 200 fs pulses with P-L=1.2 TW and 10 Hz capability. The method uses the process of relativistic self-channeling in a high-density gas jet producing electron densities in the range of 3x10(19)-6x10(20) cm(-3). In a thorough investigation, an

Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects

Obyective. Members of the box family of homeodomain-containing transcription factors, including hoxa9, hoxb3, and hoxb4 play an important role in the regulation of differentiation, proliferation and self-renewal of hematopoietic stem and progenitor cells. Lack-of-function studies using hoxa9, hoxb4, or hoxb3/hoxb4 null mice demonstrate that all these mutations compromise the repopulating ability o

Dynamic elastic pressure-volume loops in healthy pigs recorded with inspiratory and expiratory sinusoidal flow modulationRelationship to static pressure-volume loops.

Objective: The objective was to analyse relationships between inspiratory and expiratory static and dynamic elastic pressure-volume (P-el/V) curves in healthy pigs. Design: The modulated low flow method was developed to allow studies also of the expiratory P-el/V curves. Static P-el/V (P-el,P-st/V) and dynamic P-el/V (P-el,P-dyn/V) loops were studied in healthy pigs. Setting: Animal research labor

Hunting reduces recruitment of primate-dispersed trees in Amazonian Peru

Hunting with firearms decimates primates of large and medium body size (> 2 kg) that disperse the seeds of large-seeded trees. In continuous, un-fragmented forests of southeastern Peru regularly hunted with firearms for 30-40 years, large primates are extirpated and medium-sized (medium) primates are reduced 61% compared with protected forests. At hunted sites seedlings and small juveniles (< 1 m

Boronate-containing copolymers: Polyelectrolyte properties and sugar-specific interaction with agarose gel

Copolymers of N-acryloyl-m-aminophenylboronic acid (NAAPBA) with acryamide (AA), N,N-dimethylacrylamide (DMAA), and N-isopropylacrylamide (NIPAM) were found to adsorb on cross-linked agarose gel (Sepharose CL-6B) in the pH range from 7.5-9.2, due to specific boronate-sugar interactions. The molar percentages of phenylboronic acid (PBA) groups in the boronate-containing copolymers (BCCs), as estima

Mean-variance versus full-scale optimization: Broad evidence for the UK

Portfolio choice by full-scale optimization applies the empirical return distribution to a parameterized utility function, and the maximum is found through numerical optimization. Using a portfolio choice setting of three UK equity indices we identify several utility functions featuring loss aversion and prospect theory, under which full-scale optimization is a substantially better approach than t

Adsorption and Dissociation of CO on Bare and Ni-Decorated Stepped Rh(553) Surfaces

The adsorption and dissociation of carbon monoxide were studied with plane-wave density functional theory on flat Rh(111), stepped and kinked Rh(553), and Ni-decorated Rh(553) surfaces. The theoretical results were compared to high-resolution X-ray photoelectron spectroscopy (HR-XPS) experiments. The most favorable CO adsorption sites for low coverages were identified by a systematic calculation o

Cathelicidins - Nature's attempt at combinatorial chemistry

Cathelicidins are a family of diverse antimicrobial peptides found in granules of mammalian neutrophils. Cathelicidins are active against a broad range of microbes in different environments. Aside from their antimicrobial activity, cathelicidins possess other biological properties including cytotoxic activity towards mammalian cells. Several studies have shown that the amino acid sequence of cathe

Spreading introgression in the wake of a moving contact zone

An increasing number of studies describe moving hybrid zones. This raises the issue of their actual frequency and emphasizes the need for methods that enable the detection of zone movements without historical records. Asymmetric introgression, usually considered as a signature of geographical shift, might be misleading when applied to mitochondrial or potentially non-neutral markers. We investigat

Convergent Lagrangian heuristics for nonlinear minimum cost network flows

We consider the separable nonlinear and strictly convex single-commodity network flow problem (SSCNFP). We develop a computational scheme for generating a primal feasible solution from any Lagrangian dual vector; this is referred to as "early primal recovery". It is motivated by the desire to obtain a primal feasible vector before convergence of a Lagrangian scheme; such a vector is not available

Frontotemporal dementia - a clinically complex diagnosis

Objective To compare the time taken to establish a clinical diagnosis of Frontotemporal dementia (FTD) relative to a diagnosis of early onset Alzheimer's dementia (AD). Methods The data came from 89 patients under the age of 65 years, 52 of whom met the Manchester-Lund criteria for Frontotemporal dementia; 20 of these came from Lund University Hospital in Sweden. The other 32 patients with FTD alo

Partitioning of Hg between solid and dissolved organic matter in the humus layer of boreal forests

The mobility of mercury (Hg) deposited on soils controls the concentration and toxicity of Hg within soils and in nearby streams and lakes, but has rarely been quantified under field conditions. We studied the in situ partitioning of Hg in the organic top layer (mor) of podsols at two boreal forest sites differing in Hg deposition and climatic regime (S. and N. Sweden, with pollution declining to

Terrestrial mollusc succession and stratigraphy of a Holocene calcareous tufa deposit from the Fyledalen valley, southern Sweden

A Holocene calcareous tufa deposit in the Fyledalen Valley in southern Sweden was investigated with respect to molluscs, pollen, plant macrofossils and Coleoptera remains. The investigation recovered four mollusc species that today are severely threatened and included in the Swedish Red List of Endangered Species and/or the European Community's Natura 2000 programme. These include Vertigo genesii