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Large vestibular evoked myogenic potentials in response to bone-conducted sounds in patients with superior canal dehiscence syndrome

Dehiscence of the superior semicircular canal is a 'new' vestibular entity. Among these patients, the vestibular evoked myogenic potentials (VEMP) in response to air-conducted sounds are large. In the present study, VEMP in response to bone-conducted sounds were studied in 5 normal subjects, in 3 patients after ( unilateral) labyrinthectomy and in 4 patients with ( unilateral) superior canal dehis

Initial patient characteristics can predict pattern and risk of relapse in localized rhabdomyosarcoma

Purpose Evaluation of primary tumor-, treatment-, and patient-related factors predicting relapse pattern, risk, and survival after relapse with the aim to design a risk-adapted, tumor- directed surveillance program for patients with localized rhabdomyosarcoma (RMS). Patients and Methods One thousand one hundred sixty-four patients with nonmetastatic RMS achieved complete remission at the end of mu

A cost-benefit analysis of long-term management options for forests following contamination with (CS)-C-137

This paper provides a description of a cost-benefit analysis applied to determine the cost effectiveness, or otherwise, of nine management strategies potentially applicable to forests contaminated with Cs-137. Th management strategies were considered singly and in a number of likely combinations. A management strategy was considered to be cost-effective if it resulted in a lower overall monetary d

Triaxiality at high spins in Nd nuclei

The level structure of Nd-140(80) has been established up to spin 48 by in-beam gamma-ray spectroscopy using the Zr-96(Ca-48, 4n) reaction. High-fold gamma-ray coincidences were measured with the EUROBALL spectrometer. Twelve new rotational bands have been discovered at high spins, showing the change from a spherical single-particle behaviour at low spins to a deformed regime with stable triaxiali

Unidirectional electron flow in a nanometer-scale semiconductor channel: A self-switching device

By tailoring the boundary of a narrow semiconductor channel to break its symmetry, we have realized a type of nanometer-scale nonlinear device, which we refer to as self-switching device (SSD). An applied voltage V not only changes the potential profile along the channel direction, but also either widens or narrows the effective channel depending on the sign of V. This results in a diode-like char

Near-field dynamics of a turbulent round jet with moderate swirl

The near-field characteristics of a turbulent jet with moderate swirl generated by a fully developed, axially rotating pipe flow are investigated with LDV, time-resolved stereoscopic PIV measurements, as well as with large-eddy simulations. Large-scale vortical structures in either double, triple or even quadruple-helix configuration are found at the pipe exit but rapidly break down or amalgamate

Liquid crystalline phases and their dispersions in aqueous mixtures of glycerol monooleate and glyceryl monooleyl ether

The aqueous phase behavior of mixtures of 1-glycerol monooleate (GMO) and its ether analogue, 1-glyceryl monooleyl ether (GME) has been investigated by a combination of polarized microscopy, X-ray diffraction, and NMR techniques. Three phase diagrams of the ternary GMO/GME/water system have been constructed at 25, 40, and 55 degrees C. The results demonstrate that the increasing amount of GME favo

Small-x dipole evolution beyond the large-N-c limit

We present a method to include colour-suppressed effects in the Mueller dipole picture. The model consistently includes saturation effects both in the evolution of dipoles and in the interactions of dipoles with a target in a frame-independent way. When implemented in a Monte Carlo simulation together with our previous model of energy-momentum conservation and a simple dipole description of initia

Papyrus 72 and the Bodmer Miscellaneous Codex

The Bodmer miscellaneous codex contains not only P72 (Jude, 1-2 Peter), but eight other biblical and Christian writings as well. Three independent sections (I-II-III) of the codex have been identified and a different sequence than the traditional is suggested as original. There are strong connections between sections I and III and they probably followed in sequence. The most significant connection

Acid sphingomyelinase is induced by butyrate but does not initiate the anticancer effect of butyrate in HT29 and HepG2 cells

Butyric acid and sphingomyelin (SM) affect colonic tumorigenesis. We examined the potential link between butyrate stimulation and SM metabolism in colonic and hepatic cancer cell lines. After incubating HT29 and HepG2 cells with butyrate and other short-chain fatty acids, we found that butyrate increased acid but not neutral or alkaline sphingomyelinase (SMase) activity by 10- to 20-fold. The effe

Antibody mimicking polymers as chiral stationary phases in HPLC

Antibody-mimicking synthetic polymers, selective for various optically active amino acid derivatives and peptides, were prepared by noncovalent molecular imprinting. A novel approach, in which the branched, trifunctional cross-linkers pentaerythritol triacrylate and 2,2-bis(hydroxymethyl)butanol trimethacrylate were copolymerized with methacrylic acid, is described. The polymers were subsequently

BRCA2 mutations in 154 Finnish male breast cancer patients

The etiology and pathogenesis of male breast cancer (MBC) are poorly known. This is due to the fact that the disease is rare, and large-scale genetic epidemiologic studies have been difficult to carry out. Here, we studied the frequency of eight recurrent Finnish BRCA2 founder mutations in a large cohort of 154 MBC patients (65% diagnosed in Finland from 1967 to 1996). Founder mutations were detec

Self-assembled heterogeneous argon/neon core-shell clusters studied by photoelectron spectroscopy

Clusters formed by a coexpansion process of argon and neon have been studied using synchrotron radiation. Electrons from interatomic Coulombic decay as well as ultraviolet and x-ray photoelectron spectroscopy were used to determine the heterogeneous nature of the clusters and the cluster structure. Binary clusters of argon and neon produced by coexpansion are shown to exhibit a core-shell structur

Anomalous surfactant diffusion in a living polymer system

Random processes are generally described by Gaussian statistics as formulated by the central limit theorem. However, there exists a large number of exceptions to this rule that can be found in a variety of fields. Diffusion processes are often analyzed by the scaling law < r(2)>similar to t(2 beta), where the second moment of the diffusion propagator or molecular mean square displacement, < r(2)>,

Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients

Purpose: The choice of treatment for squamous cell carcinoma of the head and neck (SCCHN) is still primarily based on the tumor-node-metastasis classification. However, it is reasonable to believe that biological profiles of SCCHN may be independently associated with response to therapy. The aim of the present study was to examine genetic changes and gene expression profiles that might correlate w

Effect of two novel CGRP-binding compounds in a closed cranial window rat model

We investigated the in vivo effects of two novel calcitonin gene-related peptide (CGRP) binding molecules in the genuine closed cranial window model in the rat. The RNA-Spiegelmer (NOX-C89) and the monoclonal CGRP antibody are CGRP scavengers and might be used as an alternative to CGRP-receptor antagonists in the treatment of migraine. Rats were anaesthetized and a closed cranial window establishe