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Quality control of 99mTc-radiopharmaceuticals - Evaluation of GCS minicolumns in routine clinical work with scintillation cameras
Gel chromatography column scanning (GCS) is a rapid and reliable method for the quality control of 99mTc-radiopharmaceuticals. With this method the labelled compound and various impurities such as free pertechnetate, hydrolyzed reduced technetium or other 99mTc-complexes are obtained in one testing procedure. Using minicolumns results can be obtained with a simple testing procedure within a few mi
Blood flow in experimental liver tumors : Effect of vasoactive drugs
The effects of infused glucagon, histamine and vasopressin on blood flow in anesthetized rats with intrahepatic tumors were studied using microspheres labelled with 99Tcm or 51Cr isotopes. Considerable circulatory effects were noted both in central hemodynamic parameters as well as in organ and tissue blood flows. Glucagon infusion increased blood flow in the spleen and small intestine while hepat
Influence of vasoactive drugs on blood flow in subcutaneous tumors – an experimental study in rats
Subcutaneously implanted tumors in Wistar and Lister rats were used as a model for the study of metastatic tumor blood flow and how it is affected by vasoactive drugs. Blood flow measurements were obtained using the labelled microsphere method and the reference organ technique. Microspheres (15‐μm) labelled with either 99Tcm or 51 Cr isotopes were injected intracardially and a reference sample was
Quantitative lymphoscintigraphy. I. Basic concepts for optimal uptake of radiocolloids in the parasternal lymph nodes of rabbits
The activity-size distribution of radiocolloids has been studied using gel-chromatography scanning (GCS) of columns filled with Sepharose 4B gel. Rabbits were injected subcutaneously with the colloid of interest, laid supine beneath a gamma camera, and imaged every 15 sec for 2 to 4 hr. From the stored data, the uptakes in the parasternal lymph nodes were analyzed in terms of a two-compartment mod
Measurements of cardiac output and organ blood flow in rats using 99Tcm labelled microspheres
The cardiac output and regional blood flow have been simultaneously determined in the anesthetized rat by using the reference organ method. 99Tcm labelled dextran 15 μm microspheres were injected in the left ventricle while simultaneously an arterial reference sample was drawn at constant known rate. The values calculated regarding cardiac output agree well with previously recorded series. Regiona
Tumor blood flow in rats measured by labelled microspheres. Influence of catechol amines and the relation to adrenergic innervation of the tumor.
Quantitative lymphoscintigraphy for detection of metastases to the internal mammary lymph nodes : Biokinetics of 99tcm-sulphur colloid uptake and correlation with microscopy
Unequal Extractions : Reconceptualizing the Chinese Miner in Ghana
Over the past decade, Chinese migration to Africa has increased rapidly alongside the expansion of Chinese economic engagement with the continent. The entrance of new forms of Chinese industry, aid, commerce and resource exploration has been transformative, prompting debates over whether China in Africa is better described as neo-colonialism or a new form of beneficial developmentalism. One of the
Några reflexioner kringbegreppet ”arbetararistokrati”
I en efterskrift till boken ”Arbetararistokratin. En begreppsarkeologi” resonerar jag kring varför begreppet ”arbetararistokrati” en gång tycktes värt att analysera så pass ingående som jag gjorde. Jag anför däri 1960- och 1970-talens livaktiga samhällsvetenskapliga forskning och diskussion om arbetarklassens förborgerligande och avradikalisering. Det övergripande problem som framträder är förhåll
Arbetararistokratin : En begreppsarkeologi
I mitten av 1970-talet skrev jag tre artiklar om begreppet ”arbetararistokrati” vilka publicerades i tidskriften Arkiv för studier i arbetarrörelsens historia under rubrikerna ”Teorier om reformism och arbetararistokrati hos Engels och Lenin” nr 6 (1974), ”Arbetararistokrati och reformism. Del I: Den kommunistiska traditionen efter Lenin” i nr 11–12 (1977) samt ”Arbetararistokrati och reformism. D
An affordances apparatus for enterprise social media
The current paper addresses one of the core yet complex issues in the study of technology in organizations: the relationship between the social and the material. Many scholars in the field of Information Systems have used the notion of affordance as a lens to investigate and theorize this relationship. However, knowledge contributions in this area are often abstract and impractical, or at least co
Fabelbruk i svensk tidigmodernitet : En genrehistorisk studie
Den aisopiska fabeln etablerades som genre i den grekiska antiken och nådde Skandinavien under medeltiden. I svensk kultur upplevde fabeln en storhetstid under den tidigmoderna epoken (1500–1800). Monografin Fabelbruk i svensk tidigmodernitet. En genrehistorisk studie tar ett helhetsgrepp om fabelgenrens historia i Sverige under denna 300-årsperiod. I dialog med ny internationell fabel- och genrefEstablished as a genre in Greek antiquity, the Aesopic fable reached Scandinavia during the Middle Ages. In Sweden, the fable experienced its glory days during the early modern epoch (1500–1800). The monograph Fabelbruk i svensk tidigmodernitet. En genrehistorisk studie [Usage of Fable in Swedish Early Modernity. A Genre History] takes a comprehensive look at the history of fable in Sweden during
Cyberdiplomacy: Managing Security and Governance Online, written by Shaun Riordan
Flervetenskap - en del av universitetens DNA
Mortality and morbidity of low-grade red blood cell transfusions in septic patients : a propensity score-matched observational study of a liberal transfusion strategy
Background: Red blood cell (RBC) transfusions are associated with risks including immunological reactions and volume overload. Current guidelines suggest a restrictive transfusion strategy in most patients with sepsis but based on previous randomized controlled trials and observational studies, there are still uncertainties about the safety in giving low-grade RBC transfusions to patients with sep
Predominant and novel de novo variants in 29 individuals with ALG13 deficiency: Clinical description, biomarker status, biochemical analysis, and treatment suggestions
Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g
ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions
BACKGROUND: Expansion of type 2 innate lymphoid cells (ILC2s) in hypercholesterolaemic mice protects against atherosclerosis while different ILC2 subsets have been described (natural, inflammatory) based on their suppression of tumorigenicity 2 (ST2) and killer-cell lectin like receptor G1 (KLRG1) expression. The aim of the current study is to characterize the interleukin 25 (IL25)-induced splenic
Low Levels of CD4+CD28null T Cells at Baseline Are Associated With First-Time Coronary Events in a Prospective Population-Based Case-Control Cohort
OBJECTIVE: CD4+CD28null T cells have been shown to be associated with recurrent coronary events and suggested as potential biomarker and therapeutic target. It is unknown whether CD4+CD28null T cells associate with first-time cardiovascular events. We examined CD4+CD28null T cells in a prospective population-based cohort and in patients with advanced atherosclerosis. Approach and Results: CD4+CD28
DOTA 2 bot competition
Multiplayer online battle arena (MOBA) games are a recent huge success both in the video game industry and the international eSports scene. These games encourage team coordination and cooperation, short and long-term planning, within a real-time combined action and strategy gameplay. Artificial intelligence (AI) and computational intelligence (CI) in games research competitions offer a wide variet