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Drug-related problems in the elderly - Interventions to improve the quality of pharmacotherapy

Popular Abstract in Swedish Läkemedelsrelaterade problem hos äldre - Interventioner för att förbättra läkemedelsbehandlingen Läkare inom primärvården står för en stor del av den totala läkemedelsförskrivningen i Sverige och är en viktig målgrupp för läkemedelsindustrins information. Det har i flera uppmärksammade studier från Socialstyrelsen uppmärksammats att läkemedelsbehandlingen för patientIntroduction: Elderly people, in particular those residing in nursing homes, often use many drugs. In general elderly patients are at greater risk of experiencing drug-related problems (DRP), as they have multiple diseases, are using many drugs and have changed physiological status. Objectives: To describe the frequency of potential drug-related problems in the elderly and to evaluate different k

Study of inclusive J/psi production in two-photon collisions at LEP II with the DELPHI detector

Inclusive J/psi production in photon-photon collisions has been observed at LEP II beam energies. A clear signal from the reaction gammagamma --> J/psi + X is seen. The number of observed N(J/psi --> mu(+)mu(-)) events is 36+/-7 for an integrated luminosity of 617 pb(-1), yielding a cross-section of sigma(J/psi + X) = 45+/-9(stat) +/- 17(syst) pb. Based on a study of the event shapes of different

Gas Diffusion Through Sheets of Fibrous Porous Media

Using a cell model to describe a fibrous porous medium theoretical expressions ale deduced relating effective gas diffusivity to the volume fraction of the fibres. Cylindrical as well as band-shaped fibres are studied. The new models, which are based on solutions to the diffusion equation, agree well with existing correlations. The models are compared with experimental data for water vapour diffus

Optical properties of a silver-related defect in silicon

Doping crystalline silicon with silver results in a photoluminescence center with multiplet zero-phonon structure near 778.9 meV. We show that the published assignments of the vibronic sidebands are wrong, with severe implications for the relative transition probabilities of the luminescence transitions from the excited states. At low temperature, most of the luminescence intensity derives from th

Ett mögelsäkrare kryprum med konventionell teknik

Denna seminarieuppsats påvisar dels de avsevärda risker för mögelpåväxt som föreligger vid normala kryprum kombinerade med bjälklag i trä samt dels en enkel metod att stävja problemen nämligen medelst markisolering i kryprummet bestående av lättklinker.

Sensor fusion as a tool to monitor dynamic dairy processes

A system for monitoring milk and fat concentration in a dynamic milk/water system by fusing information from several sensors was investigated. Standard instrumentation for food production was used, the sensors were a conductivity meter, a density meter and an optical instrument used to measure backscattered light. The system was applied to a dynamic mixing situation. Prediction error did not excee

Cerebral vessel laminins and IFN-gamma y define Trypanosoma brucei brucei penetration of the blood-brain barrier

Subspecies of Trypanosoma brucei cause severe brain diseases after penetration of the blood-brain barrier. We investigated whether cytokines that modulate inflammatory cell infiltration into the brain also influence T. brucei neuroinvasion. Migration of a rodent pathogenic T. brucei strain from the cerebral blood vessels into the brain parenchyma was impeded in IFN-gamma(-/-), IFN-gamma receptor(-

Supported liquid membrane extraction for identification of phenolic compounds in the nutrient solution of closed hydroponic growing systems for tomato

The objective of the present study was to adapt and develop suitable methods to study the occurrence metabolites in the nutrient solution of hydroponically grown tomato. The organic-chemical nature of the nutrient solution from tomato grown in closed hydroponic systems was studied by supported liquid membrane technique (SLM) and analyzed by high-performance liquid chromatography (HPLC). Further, w

Dynamic phase diagram and onion formation in the system C10E3/D2O

The influence of the shear on the lamellar phase, L, of the system C10E3/D2O was studied along an isoplethal path (40 wt.% C10E3) in the temperature range 25-42degreesC. A dynamic phase diagram was determined by steady-state rheometry, where by shear action the lamellar phase was transformed into multilamellar vesicles (MLVs) ("onions"). The location of "onions" in the dynamic phase diagram, depen

Twelve- and 52-Week Efficacy of the Dipeptidyl Peptidase IV Inhibitor LAF237 in Metformin-Treated Patients With Type 2 Diabetes.

OBJECTIVE—To assess the 12- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 versus placebo in patients with type 2 diabetes continuing metformin treatment. RESEARCH DESIGN AND METHODS—We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 107 patients with type 2 diabetes with a 40-week extension in those completing the core study and agreeing, together

A systematic overview of radiation therapy effects in skeletal metastases

A systematic review of radiation therapy trials in several tumour types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for skeletal metastases is based on data from 16 randomized trials. Moreov

Bronchoscopic diagnosis of pulmonary infections in a heterogeneous, nonselected group of patients

Fiberoptic bronchoscopy with bronchoalveolar lavage and protected specimen brush technique has become an established method for etiologic diagnosis in severe forms of pulmonary infections during recent years. In this study, including 62 bronchoscopies in 53 patients, a standardized program, covering all important pulmonary pathogens, has been evaluated in a heterogeneous group of patients. Results

Influence of methotrexate, TNF blockers and prednisolone on antibody responses to pneumococcal polysaccharide vaccine in patients with rheumatoid arthritis.

Objective. To compare antibody responses to 23-valent pneumococcal vaccine (Pneumovax (R)) in controls and patients with established rheumatoid arthritis (RA) treated with TNF blockers, methotrexate (MTX) or a combination of both. Methods. Patients with RA (n = 149) and healthy controls (n = 47) were vaccinated. Treatment with TNF blockers (etanercept or infliximab) and MTX was given to 50 patient

Continuity of leisure participation from middle age to old age

Objectives. Continuity in habits, activities, and roles is important upon entering old age according to the continuity theory of aging. Few studies have investigated patterns of leisure participation over an extended period of time among older adults. This study examines changes in nine different leisure activities in a nationally representative sample of individuals followed over a 34-year period