Spotted fever group (SFG) Rickettsia species are inoculated into the mammalian bloodstream by hematophagous arthropods. Once in the bloodstream and during dissemination, the survival of these pathogens is dependent upon the ability of these bacteria to evade serum-borne host defenses until a proper cellular host is reached. Rickettsia conorii expresses an outer membrane protein, Adr1, which binds

Moraxella catarrhalis is part of the normal bacterial flora in the nasopharynx of children, although over the past two decades, it has emerged as a significant bacterial pathogen and not simply a commensal colonizer. Moraxella catarrhalis is a common bacterial species cultured from the nasopharynx of children during otitis media episodes, with the patterns of nasopharyngeal colonization by microor

Peptostreptococcus micros is a commensal of the oral cavity and the genitourinary tract that rarely causes serious infections. A case of a destructive knee joint infection with rapid progress caused by P. micros is presented. The significance of the microbiological findings was initially not acknowledged, which contributed to a nonsuccessful clinical outcome.

Background - Intravascular thrombosis occurs in disorders of diverse pathogeneses, including allograft and xenograft rejection. In this in vitro study, we describe an approach for tethering the specific thrombin inhibitor hirudin to plasma membranes as part of a genetic strategy for regulating intravascular coagulation. Methods and Results - An HLA class I leader sequence was fused with hirudin li

Is common ownership the Doomsday Machine for the operation of free markets, competition and capitalism as we know it? An observer of cutting-edge law and economics literature may indeed tend to believe that we are approaching a point of ultimate antitrust apocalypse. This article tries to unfold the ongoing antitrust-focused debate by exploring a series of questions: i) who is a common owner; ii)

The sFLASH project at DESY is an experiment to study direct seeding using a source based on the high-harmonic generation (HHG) process. In contrast to SASE, a seeded FEL exhibits greatly improved longitudinal coherence and higher shot-to-shot stability (both spectral and energetic). In addition, the output of the seeded FEL is intrinsically synchronized to the HHG drive laser, thus enabling pump-p

We examine the construction of electromagnetism in its current form, and in an alternative form, from a point of view that combines a minimal realism with strict rational demands. We begin by discussing the requests of reason when constructing a theory and next, we follow the historical development as presented in the record of original publications, the underlying epistemology (often explained by

Background: Large animal models are important in atrial fibrillation (AF) research, as they can be used to study the pathophysiology of AF and new therapeutic approaches. Unlike other animal models, horses spontaneously develop AF and could therefore serve as a bona fide model in AF research. We therefore aimed to study the electrical, functional and structural remodelling caused by chronic AF in

Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology has remained controversial mainly due to the lack of serological methods that can distinguish the two viruses. A novel multiplex serological assay measuring IgG reactivity against the immediate-early protein 1 from HHV-6A (IE1A) and HHV-6B (IE1B) was used in a MS cohort (8,742 persons with MS and 7,215 matched con

Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffold

Climate change shocks and stresses are expected to increasingly affect urban areas in Sub-Sahara Africa (SSA). However, there remain gaps in understanding local precipitation extremes and influential factors that can enhance urban resilience. This study synthesized determinants of urban resilience, investigated historic and projected precipitation extremes up to the year 2050. Also assessed were f

I ett Europa där gränskontroller intensifieras och deportationer ökar ställer denna avhandling frågor om möjligheter till motstånd och aktivism genom teater. Den tar sin utgångspunkt i en deltagande etnografisk undersökning av No Border Musical. No Border Musical skapades och sattes upp i Malmö under 2011–2013. Initiativet togs av personer kopplade till den lokala flyktingrättsrörelsen. Ungefär häIn a context of deportability and bordering practices, this thesis asks questions regarding possibilities and limitations of resistance through community theatre. It sets out from a participatory ethnographic exploration of the working process and performance of the No Border Musical. The No Border Musical was created in 2011–2013 in the city of Malmö in southern Sweden. It was initiated by people

The arctic tern Sterna paradisaea completes the longest known annual return migration on Earth, traveling between breeding sites in the northern arctic and temperate regions and survival/molt areas in the Antarctic pack-ice zone. Salomonsen (1967, Biologiske Meddelelser, Copenhagen Danske Videnskabernes Selskab, 24, 1) put forward a hypothetical comprehensive interpretation of this global migratio

A numerical study was conducted to investigate the mechanism of laminar flow and heat transfer enhancement in an interrupted microchannel heat sink (IMCHS) with different shaped ribs at Reynolds number ranging from 100 to 900. The global flow features, heat transfer and friction for IMCHS with no ribs, rectangle ribs, triangle ribs and trapezoid ribs are detailed compared. The results show that th