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Vitamin D status and dental caries in healthy Swedish children

Background: Vitamin D is crucial for mineralized tissue formation and immunological functions. The purpose of this study was to evaluate the association between vitamin D status and dental status in healthy children with vitamin D supplementation in infancy and at 6 years of age. Method: Eight-year-old children who had participated in a vitamin D intervention project when they were 6 years old wer

A Method for Investigation of Size-Dependent Protein Binding to Nanoholes Using Intrinsic Fluorescence of Proteins

We have developed a novel method to study the influence of surface nanotopography on human fibrinogen adsorption at a given surface chemistry. Well-ordered arrays of nanoholes with different diameters down to 45 nm and a depth of 50 nm were fabricated in silicon by electron beam lithography and reactive ion etching. The nanostructured chip was used as a model system to understand the effect of siz

Assessment on abrasiveness of high chromium cast iron material on the wear performance of PCBN cutting tools in dry machining

Polycrystalline Cubic Boron Nitride (PCBN) has been considered as the main cutting tool material for hard turning, which has the comparable surface finish quality as grinding, and high efficiency, economical technology in production. It is well known that the abrasiveness of the workpiece have the very important role of the machinability of the materials. Therefore, the tool wear of the PCBN inser

Can MM/GBSA calculations be sped up by system truncation?

We have studied whether calculations of the binding free energy of small ligands to a protein by the MM/GBSA approach (molecular mechanics combined with generalized Born and surface area solvation) can be sped up by including only a restricted number of atoms close to the ligand. If the protein is truncated before the molecular dynamics (MD) simulations, quite large changes are observed for the ca

Effects of barley variety, dietary fiber and β-glucan content on bile acid composition in cecum of rats fed low- and high-fat diets

Diet-induced obesity and insulin resistance have been linked to changes in bile acid (BA) profiles, which in turn are highly dependent on the dietary composition and activity of the gut microbiota. The objective of the present study was to investigate whether the type and level of fiber had an effect on cecal BA composition when included in low- and high-fat diets. Groups of rats were fed two barl

Disaggregation of SMOS soil moisture over West Africa using the Temperature and Vegetation Dryness Index based on SEVIRI land surface parameters

The overarching objective of this study was to produce a disaggregated SMOS Soil Moisture (SM) product using land surface parameters from a geostationary satellite in a region covering a diverse range of ecosystem types. SEVIRI data at 15 min temporal resolution were used to derive the Temperature and Vegetation Dryness Index (TVDI) that served as SM proxy within the disaggregation process. West A

Individual factors associated with neck disability in patients with cervical radiculopathy scheduled for surgery : A study on physical impairments, psychosocial factors, and life style habits

Purpose: The influence of individual factors on patient-reported outcomes is important in the interpretation of disability and treatment effectiveness. The purpose of this study was to assess how physical impairments, psychosocial factors, and life style habits were associated with neck disability based on the Neck Disability Index (NDI), in patients with cervical radiculopathy scheduled for surge

Altered pain perception in children with chronic tension-type headache : is this a sign of central sensitisation?

AIM: The aim of this article is to investigate if children (7-17 years) with frequent episodic tension-type headache (FETTH) or chronic TTH (CTTH) have an altered pain perception compared to healthy controls.METHODS: We applied a pressure of five increasing intensities to m. trapezius and m. temporalis with a Somedic Algometer II. Visual analogue scale-score was rated and area under the curve (AUC

Modeling the forest phosphorus nutrition in a southwestern Swedish forest site

In this study, a phosphorus (P) module containing the biogeochemical P cycle has been developed and integrated into the forest ecosystem model ForSAFE. The model was able to adequately reproduce the measured soil water chemistry, tree biomass (wood and foliage), and the biomass nutrient concentrations at a spruce site in southern Sweden. Both model and measurements indicated that the site showed s

Protein-water interactions studied by molecular dynamics simulations

Most proteins have evolved to function optimally in aqueous environments, and the interactions between protein and water therefore play a fundamental role in the stability, dynamics, and function of proteins. Although we understand many details of water, we understand much less about the protein-water interface. In this thesis we use molecular dynamics (MD) simulations to cast light on many struct

Multiuser Bandwidth Minimization with Individual Rate Requirements for Non-Orthogonal Multiple Access

Non-Orthogonal Multiple Access (NOMA) for a multi-user single- input single-output (SISO) setup is studied in the power and the frequency domains simultaneously. The problem of sum-bandwidth minimization under perfect channel state information is solved for various combinations of rate requirements and user pairings. In this process, an iterative Tabu-search based algorithm is applied to avoid an

Acupuncture treatments for infantile colic : a systematic review and individual patient data meta-analysis of blinding test validated randomised controlled trials

Objective: Needle acupuncture in small children has gained some acceptance in Western medicine. It is controversial, as infants and toddlers are unable to consent to treatment. We aimed to assess its efficacy for treating infantile colic. Design: A systematic review and a blinding-test validation based on individual patient data from randomised controlled trials. Primary end-points were crying tim

Bandwidth Minimization under Probabilistic Constraints and Statistical CSI for NOMA

Non-Orthogonal Multiple Access (NOMA) is studied under statistical Channel State Information (CSI) and probabilistic constraints. Unlike the conventional power domain only NOMA, the definition of NOMA here considers both the power and the frequency domains simultaneously, where a flat power spectrum is assumed for each UE. This increases the capacity region when compared to the conventional definiti

Precoder Design for Cooperative Multi-User Downlink MISO Channels with Finite Side-Link Capacity

For a pair of closely located and cooperating user equipments (UEs), a precoder is designed at the base station (BS) which considers the UE cooperation. The UEs collaborate over an out-of-band side-link with a finite capacity. The side-link may be used for interference cancellation (IC) or for relaying decoded symbols. The precoder has two parts, a cooperative part based on channel inversion and a

Long-lasting cervical radicular pain managed with surgery, physiotherapy, or a cervical collar. : A prospective, randomized study

STUDY DESIGN: This prospective, randomized study compares the efficacy of surgical and conservative treatments in patients with long-lasting cervical radicular pain.OBJECTIVES: To compare the effects of surgery, physiotherapy, and a cervical collar.SUMMARY OF BACKGROUND DATA: There are no previous controlled outcome studies that have compared surgical treatment with nonsurgical treatment of patien

Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms

Background: Echolucent carotid plaques have been related to an increased risk of ischemic cerebrovascular events. The aim of the present study was to evaluate whether a new objective ultrasonographic parameter, the statistical geometric feature (SGF), reflecting spottiness of carotid plaques, can be associated with cerebrovascular symptoms and with a rupture-prone plaque phenotype. Methods: The pl

Pain, muscular tenderness, cervical and shoulder mobility in patients with cervical radiculopathy randomly treated with surgery, physiotherapy or a cervical collar

This prospective, randomised study compares the efficacy of surgery and conservative treatments in patients with cervical radiculopathy. The study group comprised 81 patients with long-lasting cervicaloradiculopathy, with a pain distribution corresponding to a significant nerve root compression, verified by magnetic resonance imaging or computed tomographic myelography. The patients were randomly

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