Autoimmune thrombocytopenic purpura (AITP) is a bleeding disorder in which autoantibodies are directed against an individual's own platelets, leading to enhanced clearance through Fc receptor (R)-mediated phagocytosis by macrophages residing in the reticuloendothelial system, particularly in the spleen. Although the immunopathogenesis of the disease is autoantibody-mediated, there is now substanti

En este trabajo se analizan ocurrencias de Pretérito Perfecto Compuesto (PPC) en entrevistas a personalidades del quehacer político y cultural de España y México. La elección del PPC en estos dialectos a menudo es caracterizada, según el caso, por codificar situaciones imperfectivas o situaciones que implican relevancia actual, en contraposición del Pretérito Perfecto Simple que implica situacioneThis paper analyzes occurrences of the Spanish compound past [“present perfect”, PPC] in interviews to personalities of the political and cultural life of Mexico and Spain. The choice of the PPC in theses dialects is often characterized by its codification of imperfective situations or situations that denote current relevance depending on the case, thus countering the Simple Past that comprises si

Over the years, technological developments and societal changes have forced companies to modify their organizing practices. Companies operating in the construction sector are no exception, but due to their project-based structure, it is more difficult to coordinate change initiatives. Indeed, the construction sector is often described as conservative and unwilling to adopt change. However, there i

Sexuality in the Swedish Police is based on the experiences of lesbian, gay and bisexual police officers and the author's observations of police work. Written at the intersection of organizational, gender and police studies, the book analyses how processes of exclusion and inclusion of LGB sexuality coexist in the Swedish police, how these processes are related to the culture and characteristics o

Floral traits are shown to covary predictably with local pollinators by a growing number of studies, and linking this variation to fitness can help to gain an even more predictive view. Pollinators have long been recognized to drive trait evolution in plants and plant communities. Most studies searching for patterns in how pollination affects plants do not consider that pollinator selection might

Genetic HINT to a gender reveal Reproduction is an essential process in order to ensure the survival and propagation of the species. Many processes of sexual and asexual reproduction are seen in nature. The sex of the progeny constitutes an essential factor in reaping the maximum benefits associated with the individual. In fields like poultry and dairy, knowledge on the sex-determination method c

Interactions between biomolecules are ubiquitous in nature and crucial to many applications including vaccine development; environmentally friendly textile detergents; and food formulation. Using small angle X-ray scattering and structure-based molecular simulations, we explore protein–protein interactions in dilute to semi-concentrated protein solutions. We address the pertinent question, whether

The significance of systemic chemotherapy (SCT) combined with hepatic arterial infusion (HAI) chemotherapy in the treatment of pancreatic ductal adenocarcinoma with liver metastases (PACLM) remains unclear. Based on previous studies, this single-center propensity score matching (PSM) study aimed to explore the efficacy of SCT with or without HAI for PACLM.

A modularly interactive CRISPR system Climate change and the growing human population already pose severe challenges for food security and agricultural businesses around the globe. One key component on a way to a more sustainable agriculture that has the ability to adapt to changing environmental conditions could be the newly arisen genome editing. A form of ge- netic engineering that allows for