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Obstacle Comparisons to Achieving Distance Learning and Applying Electronic Exams during COVID-19 Pandemic

This study aims to identify obstacles and barriers to achieving quality distance learning and the use of electronic exams, comparing them to pursue success in the distance education system during the coronavirus pandemic (COVID-19). It also aimed to determine the similarity and differences between the two main components of distance education. This is based on a sample of evaluations from professo

Spectral Characterization of Functional MRI Data on Voxel-Resolution Cortical Graphs

The human cortical layer exhibits a convoluted morphology that is unique to each individual. Conventional volumetric fMRI processing schemes take for granted the rich information provided by the underlying anatomy. We present a method to study fMRI data on subject-specific cerebral hemisphere cortex (CHC) graphs, which encode the cortical morphology at the resolution of voxels in 3-D. Using graph

Tipping elements and amplified polar warming during the Last Interglacial

Irreversible shifts of large-scale components of the Earth system (so-called ‘tipping elements’) on policy-relevant timescales are a major source of uncertainty for projecting the impacts of future climate change. The high latitudes are particularly vulnerable to positive feedbacks that amplify change through atmosphere-ocean-ice interactions. Unfortunately, the short instrumental record does not

Incidence of distal radius fracture in a general population in southern Sweden in 2016 compared with 2001

Summary: In this population-based study, we compared the incidence of distal radius fracture in 2016 with that in the same region’s adult general population in 2001 using radiographs to identify fracture cases. We showed that the incidence decreased by 24% in 2016 compared with 2001 indicating an important development. Introduction: We conducted an epidemiological study on residents of northeaster

Degrowth: New roots for the economy : Re-imagining the future after the corona crisis

This letter is the result of a collaborative process within the degrowth international network. It has been endorsed by more than 2,000 signatories and over 70 organizations from more than 60 countries. All the people whose names are listed have been part the working group writing it. The letter has been published in outlets such as OpenDemocracy (UK), Information (Denmark), Mediapart (France), Th

Tuning lipid structure by bile salts: Hexosomes for topical administration of catechin

The delivery of bio-active molecules through the skin is challenging given the complex structure of its outer layer, the stratum corneum. Here we explore the possibility to encapsulate natural compounds into nanocarriers containing permeation enhancers that can affect the fluidity of the stratum corneum lipids. This approach is expected to facilitate dermal or transdermal release. For this purpose

Processes of ‘hummocky moraine’ formation in the Gaick, Scotland : insights into the ice-marginal dynamics of a Younger Dryas plateau icefield

Younger Dryas ice-marginal (‘hummocky’) moraines in Scotland represent valuable terrestrial archives that can be used to obtain important information on ice-marginal dynamics and glacier thermal regimes during a period of rapid climatic change. In this paper, we present detailed sedimentological studies of Younger Dryas ice-marginal moraines in the Gaick, central Scotland, the former site of a spa

Prospective validation of microseminoprotein-β added to the 4Kscore in predicting high-grade prostate cancer in an international multicentre cohort

Objectives: To prospectively evaluate the performance of a pre-specified statistical model based on four kallikrein markers in blood (total prostate-specific antigen [PSA], free PSA, intact PSA, and human kallikrein-related peptidase 2), commercially available as the 4Kscore, in predicting Gleason Grade Group (GG) ≥2 prostate cancer at biopsy in an international multicentre study at three academic

Efficient Photosynthetic Functioning of Arabidopsis thaliana Through Electron Dissipation in Chloroplasts and Electron Export to Mitochondria Under Ammonium Nutrition

An improvement in photosynthetic rate promotes the growth of crop plants. The sink-regulation of photosynthesis is crucial in optimizing nitrogen fixation and integrating it with carbon balance. Studies on these processes are essential in understanding growth inhibition in plants with ammonium ((Formula presented.)) syndrome. Hence, we sought to investigate the effects of using nitrogen sources wi

On mesh dependencies in finite-element-based damage prediction : application to sheet metal bending

The properties of a local and a regularised gradient-enhanced continuum damage model are highlighted and both types of models are applied to the simulation of an air bending process. Constitutive relations are summarised for both Lemaitre-type models and a brief description of their implementation into Abaqus user material subroutines is given. With (several) material parameters obtained from a ba

In Vivo Veritas : 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors

Glycomimetic drugs have attracted increasing interest as unique targeting vectors or surrogates for endogenous biomolecules. However, it is generally difficult to determine the in vivo pharmacokinetic profile of these compounds. In this work, two galectin-3 inhibitors were radiolabeled with fluorine-18 and used as surrogate PET tracers of TD139 and GB1107. Both compounds are promising drugs for cl

Improving musculoskeletal health for children and young people – A ‘call to action’

This chapter describes the musculoskeletal (MSK) context in children and young people as an important contributor to the global non-communicable disease burden. Through selected MSK conditions, we describe the impact on patients, families and communities and highlight the challenges that need to be addressed. We focus on opportunities for better working together and describe exemplar initiatives t

Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death : an analysis of 712 cases

Background: Lemierre syndrome is characterized by head/neck vein thrombosis and septic embolism usually complicating an acute oropharyngeal bacterial infection in adolescents and young adults. We described the course of Lemierre syndrome in the contemporary era. Methods: In our individual-level analysis of 712 patients (2000–2017), we included cases described as Lemierre syndrome if these criteria

Comparative outcome of double lung transplantation using conventional donor lungs and non-acceptable donor lungs reconditioned ex vivo.

A method to evaluate and recondition lungs ex vivo has been tested on donor lungs that have been rejected for transplantation. In the present paper, we compare early postoperative course between the six patients who received reconditioned lungs and the patients who received conventional donor lungs during the same period of time. During 2006 and 2007, a total of 21 patients underwent double sequen

Elevated Plasma Homocysteine Level Is Not Primarily Related to Alzheimer's Disease.

Background: A moderate elevation of plasma total homocysteine (tHcy) is considered a potential risk factor for Alzheimer's disease (AD). Methods: We have investigated the main determinants (age, renal impairment, cobalamin/folate status and the presence of vascular disease) of plasma tHcy in 326 patients with AD, and also in 281 patients with mild cognitive impairment (MCI), since about half of th

δ' potential arising in exterior complex scaling

In the method of exterior complex scaling the coordinates of the Hamilton operator are scaled by a constant factor starting at a radius R≠0. We show that this procedure induces a singularity in the kinetic-energy term which must be interpreted as the derivative of a δ function.