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A national study of BRCA1 and BRCA2 mutations in Danish HBOC (Hereditary Breast Ovarian Cancer) families revealed a total number of 322 mutation positive families, 206 (64%) BRCA1 and 116 (36%) BRCA2 positive families from a population of 5.5 million inhabitants. Seven hundred and twenty six mutation positive individuals were identified: 402 female BRCAl carriers, 79 male BRCAl carriers, 213 femal
The article tells the modern love story of the organic grower Eduardo and the people who savor his apples. One remarkable paradigm shift when it comes to contemporary food culture is that the product’s social, political and cultural entanglements are no longer hidden from view. This new context has created platforms where producers and consumer come together to co-produce. Here, I broaden the conc
Homonymous hemianopia (HH) is an anisotropic visual impairment characterized by the binocular inability to see one side of the visual field. Patients with HH often misperceive visual space. Here we investigated how HH affects visual motor control. Methods and Findings: Seven patients with complete HH and no neglect or cognitive decline and seven gender- and age-matched controls viewed displays in
The Swedish population-based acute myeloid leukemia registry contains data from 3251 patients (excluding acute promyelocytic leukemia) diagnosed between 1997 and 2006. Informative cytogenetic data from 1893 patients were retrospectively added, including 1054 patients aged between 60 and 79 years. Clonal abnormalities were found in 57% of the informative karyotypes. Karyotypic patterns differed by
High kinetic-energy photoelectron spectroscopy (HIKE) or hard x-ray photoelectron spectroscopy has been used to investigate the alloying of Ni/Cu (100) multilayers. Relative intensities of the corelevels and their chemical shifts derived from binding energy changes are shown to give precise information on physicochemical properties and quality of the buried layers. Interface roughening, including
Background: Knowledge about the relation between user involvement in the provision of assistive technology and outcomes of assistive technology use is a prerequisite for the development of efficient service delivery strategies. However, current knowledge is limited, particularly from low-income countries where affordability is an issue. The objective was therefore to explore the relation between o
Background: 112 patients who received small and medium sized St.Jude Regent heart valves (19-25 mm) at 7 Scandinavian centers were studied between January 2003 and February 2005 to obtain non-invasive data regarding the hemodynamic performance at rest and during Dobutamine stress echocardiography (DSE) testing one year after surgery. Material and methods: 46 woman and 66 men, aged 61.8 +/- 9.7 (18
We present an assessment of the barium abundance ratios for red giant member stars in the faint Hercules dwarf spheroidal (dSph) galaxy. Our results are drawn from intermediate-resolution FLAMES/GIRAFFE spectra around the Ba II 6141.71 angstrom absorption line at low signal-to-noise ratios. For three brighter stars we were able to gain estimates from direct equivalent-width measurements, while for
The neuropsychological network is a complex structure. To identify processes location and network capacity the brain imaging techniques together and in combination with other neuropsychological techniques and the expanding of well elaborated designs provide us with a multidimensional understanding, and contributes to the understanding of each illicit drug's character, which is of importance in des
Jordan has seen a large increase in inhabitants over the past five decades as a result of a high population growth rate and forced migrations. Economic and cultural development has improved the standard of living and changed consumer habits, resulting in an increase in the volume of municipal solid waste (MSW) over time. The rate of production of MSW has been estimated at about 1,964,284 ton annua
In this review we describe the development and current status of free clusters studied using core-level spectroscopies. This topic ranges from simple model systems, such as rare gas clusters, to molecular clusters, and clusters of solids, held together by ionic, covalent and metallic bonding. (C) 2009 Elsevier B.V. All rights reserved.
Background: While simultaneous saccharification and co-fermentation (SSCF) is considered to be a promising process for bioconversion of lignocellulosic materials to ethanol, there are still relatively little demo-plant data and operating experiences reported in the literature. In the current work, we designed a SSCF process and scaled up from lab to demo scale reaching 4% (w/v) ethanol using xylos
Background: Genome wide gene expression data is a rich source for the identification of gene signatures suitable for clinical purposes and a number of statistical algorithms have been described for both identification and evaluation of such signatures. Some employed algorithms are fairly complex and hence sensitive to over-fitting whereas others are more simple and straight forward. Here we presen
A 4 Gbit/s radio link using impulse-based on-off keying at 60 GHz is demonstrated. The input baseband signals are transferred to radio frequency wavelets through direct conversion, by switching a GaAs gated tunnel diode oscillator on and off. The wavelet generator drives an antenna directly without any buffer or power amplifier. The peak output power is - 11 dBm at a power consumption of 30 mW. Th
European energy policy aims to shift the energy market towards an increased focus on energy services based on end-user needs. This requires a close understanding of the role of end-users and their needs and practices. Based on a European project called CHANGING BEHAVIOUR, we examine the interaction between energy users and energy efficiency practitioners. Using previous cases and our own pilots as
