Accurate assessment of early hip joint cartilage alterations may help optimize patient selection and follow-up of hip joint preservation surgery. Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) is sensitive to the glycosaminoglycan content in cartilage that is lost early in the development of osteoarthritis (OA). Hence, the dGEMRIC technique holds promise for the deve

The recognition of pathogen-derived structures by C-type lectins and the chemotactic activity mediated by the CCL2/CCR2 axis are critical steps in determining the host immune response to fungi. The present study was designed to investigate whether the presence of single nucleotide polymorphisms (SNPs) within DC-SIGN, Dectin-1, Dectin-2, CCL2 and CCR2 genes influence the risk of developing Invasive

Background and Aims: While the development of type 1 diabetes (T1D) in childhood is in part genetically conditioned, non-genetic/environmental factors seem to play a decisive role in its aetiology. The incidence of T1D has been increasing rapidly during the last years, and its prevalence is higher in countries of high economical welfare like Sweden. Therefore, both from an aetiological and a publi

A critical source publication of an unknown letter from the late eighteenth century, of great importance for the later interpretation of the German Moravian spiritual tradition in Sweden.

Popular Abstract in Swedish Hjärtsvikt är en sjukdom som beror på att hjärtat inte kan pumpa ut tillräckligt med blod till kroppens vävnader. I Sverige drabbas årligen 30000 personer av hjärtsvikt, och prognosen är jämförbar med de vanligaste cancerformerna. Trots att det är så vanligt och allvarligt, saknas i dagsläget objektiva mått på hjärtsvikt – det finns alltså ingen ”linjal” för att mäta huHeart failure is a clinical syndrome characterized by an inability of the heart to meet the metabolic demands of the body. Approximately 1-2% of the population in the western society has the diagnosis, and the 5-year mortality rate is comparable with the common cancer diagnoses. The lack of reliable objective measures of heart failure motivates research in this direction. Blood flow is an essentia

In a linguistic description there is normally a more or less conspicious lack of balance between the space a phenomenon requires to be fully described and its frequence in actual language usage, here called a lack of iconicity. The article investigates to what degree some Danish and Swedish dictionaries are iconical in this sense, i.e. whether the space of a word in the dictionary corresponds with

Purpose An advanced 3/4PL-relationship in which the logistics service provider extended normal services by taking ownership of the goods during global distribution, is studied. We describe and analyze the approach to the legal rules a 3/4PL provider and its client company took in their contract, and present some remarks on the extent to which these contract solutions are legally sound. Design/me

Changing illumination constitutes a serious challenge for video segmentation algorithms, especially in outdoor scenes under cloudy conditions. Rapid illumination changes, e.g. caused by varying cloud cover, often cause existing segmentation algorithms to erroneously classify large parts of the image as foreground. Here a method that extends existing segmentation algorithms by detecting illuminatio

Aims To evaluate premature mortality and causes of death from young adulthood to middle age in a cohort of drug users followed during almost four decades Design Follow-up study of a consecutive cohort of patients with drug abuse/dependence. Methods A cohort of 561 drug abusers, admitted to a detoxification and short-term rehabilitation unit 1970–1978 was followed to December 31st, 2006. Standard

Background: Resource allocation in public health care principally involves politicians, administrators, and physicians. They all have their different roles, agendas and ambitions when it comes to how public health care resources should be spent. Previous studies on attitudes among health-care stakeholders have mainly focused on views and preferences among clinical decision-makers, while less atten

Review of G. Kurt Piehler (ed.), The United States in World War II. A Documentary Reader.

Dissolved organic carbon (DOC) is one of the most active and mobile carbon pools, and thus an important component of the global carbon cycle. Previous research on DOC transport in the soil and on factors controlling DOC export towards the river system focused mainly on forest and wetland areas, with only limited information available from agricultural soils. We carried out rainfall simulations on

Globular proteins are folded polypeptide structures comprising stretches of secondary structures (helical (alpha- or 3(10) helix type), polyproline helix or beta-strands) interspersed by regions of less well-ordered structure ("random coil"). Protein fold prediction is a very active field impacting inte alia on protein engineering and misfolding studies. Apart from the many studies of protein refo

Smoking is usually initiated early in life and most adult regular smokers have started smoking before 18 years of age. A younger age at smoking initiation is associated with risk taking behaviours and worse health outcomes regarding psychological and somatic conditions, suggested to be caused by exposure during critical developmental periods. The present study aims to investigate self-rated health

Whole-cell recordings were obtained from mossy fibre terminals in adult turtles in order to characterize the basic membrane properties. Calcium imaging of presynaptic calcium signals was carried out in order to analyse calcium dynamics and presynaptic GABA B inhibition. A tetrodotoxin (TTX)-sensitive fast Na+ spike faithfully followed repetitive depolarizing pulses with little change in spike dura