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Zooming in on eukaryotic translation initiation.
Does variability in cognitive performance correlate with frontal brain volume?
Little is known about the neural correlates of within-person variability in cognitive performance. We investigated associations between regional brain volumes and trial-to-trial, block-to-block, and day-to-day variability in choice-reaction time, and episodic and working memory accuracy. Healthy younger (n=25) and older (n=18) adults underwent 101 daily assessments of cognitive performance, and th
Evaluation of Analytical Measures of Map Legibility
The generation of maps in real-time web-services introduces challenges concerning map legibility. As these services lack the important input of a traditional cartographer, analytical measures of the legibility are called for. The aim of this study was to develop such legibility measures, and to evaluate them with the help of expert users. Measures of the amount of information, spatial distribution
Distribution of artificial gamma-ray emitting radionuclide activity concentration in the top soil in the vicinity of the Ignalina Nuclear Power Plant and other regions in Lithuania
The impact of the operating Ignalina Nuclear Power Plant (INPP) on the contamination of top soil layer with artificial radionuclides has been studied. Results of the investigation of artificial gamma-ray emitting radionuclide distribution in soil in the vicinity of the INPP and distant regions in Lithuania in 1996-2008 (INPP operational period) show that nowadays Cs-137 remains the most important
A new route towards colloidal molecules with externally tunable interaction sites.
We describe a route towards self-assembled colloidal molecules, where thermoresponsive microgels serve as discrete, externally tunable interaction sites. The ability of poly(N-isopropylacrylamide) (PNIPAM) and poly(N-isopropylmethacrylamide) (PNIPMAM) microgels to adsorb to the oil/water (O/W) interface and create Pickering-stabilized mini-emulsions was first tested using the controlled addition o
Human physiological benefits of viewing nature: EEG responses to exact and statistical fractal patterns.
Psychological and physiological benefits of viewing nature have been extensively studied for some time. More recently it has been suggested that some of these positive effects can be explained by nature's fractal properties. Virtually all studies on human responses to fractals have used stimuli that represent the specific form of fractal geometry found in nature, i.e. statistical fractals, as oppo
Long-term psychiatric consequences of exposure to trauma in Cambodia: A regional household survey.
The long-term psychiatric consequences of exposure to war and/or mass conflict continue to be of great concern and particularly in Cambodia. The current cross-sectional study examined the relationship between history of trauma and current psychiatric and functional morbidity in 3200 randomly selected adults aged 18-60 in Cambodia. Structured interviews were conducted from November 2011 until May 2
Osteoarthritis and Activity-An Analysis of the Relationship Between Eburnation, Musculoskeletal Stress Markers (MSM) and Age in Two Neolithic Hunter-Gatherer Populations from Gotland, Sweden
The occurrence of osteoarthritis (OA) as an indicator of physical activity was explored in two Middle Neolithic samples from Gotland (c. 3400-2300 BC) in the Baltic Sea: Ajvide (n = 46) and Vasterbjers (n = 32). The difficulty in diagnosing OA is recognised and only eburnation was used as a definite criterion for OA. The relationship between eburnation lesions and Musculoskeletal Stress Markers (M
Distinct impacts of different mammalian herbivore assemblages on arctic tundra CO2 exchange during the peak of the growing season
Herbivores play a key role in the carbon (C) cycle of arctic ecosystems, but these effects are currently poorly represented within models predicting land-atmosphere interactions under future climate change. Although some studies have examined the influence of various individual species of herbivores on tundra C sequestration, few studies have directly compared the effects of different herbivore as
The benthic foraminiferal record of the Medieval Warm Period and the recent warming in the Gullmar Fjord, Swedish west coast
A high-resolution study of benthic foraminiferal assemblages was performed on a ca. eight metre long sediment core from Gullmar Fjord on the west coast of Sweden. The results of Pb-210- and AMS C-14-datings show that the record includes the two warmest climatic episodes of the last 1500 years: the Medieval Warm Period (MWP) and the recent warming of the 20th century. Both periods are known to be a
Former Male Elite Athletes Have Lower Incidence of Fragility Fractures than Expected.
PURPOSE: Physical activity during growth is associated with high peak bone mass and may, as a result, prevent osteoporosis later in life. It is therefore possible that athletic activity during youth could lower the risk of fragility fractures in old age. Though, this is currently unclear and, based on evaluations of surrogate skeletal end point variables in former athletes, we hypothesized that th
Scale factors and hypothetical referenda: A clarifying note
In this note we explore in detail the importance of, and problems associated with, correcting for variance differences between data sets obtained from hypothetical and real referenda. We show that a previous discussion in the literature rests on a problematic estimation of the relative scale factor. The implications are illustrated with data from Cummings et al. (1997) [5], as well as with simulat
Prognostic Implications of Mutations in NOTCH1 and FBXW7 in Childhood T-ALL Treated According to the NOPHO ALL-1992 and ALL-2000 Protocols
BackgroundIn children, T-cell acute lymphoblastic leukemia (T-ALL) has inferior prognosis compared with B-cell precursor ALL. In order to improve survival, individualized treatment strategies and thus risk stratification algorithms are warranted, ideally already at the time of diagnosis. ProcedureWe analyzed the frequency and prognostic implication of mutations in NOTCH1 and FBXW7 in 79 cases of S
Trends in European tourism planning and organisation
Compression of CEP-stable multi-mJ laser pulses down to 4 fs in long hollow fibers
Carrier-envelope phase stable 4 fs near-IR pulses with 3 mJ energy were generated by spectral broadening of circularly polarized 8 mJ pulses in a differentially pumped 2 m long composite stretched flexible hollow fiber. The pulses were characterized using both second-harmonic generation frequency-resolved optical gating (SHG-FROG) and SHG d-scan methods.
First Report on Metastasizing Small Bowel Carcinoids in First-Degree Relatives in Three Generations
Background/Aims: There is an established association between the multiple endocrine neoplasia type 1 (MEN 1) syndrome and foregut carcinoids. Some registry studies also indicate that offspring to carcinoid patients run an increased risk of developing a carcinoid tumor themselves. However, there are only scattered reports of gastrointestinal carcinoids in two generations. The aim of this study was
TRITON and Beyond: New Insights into the Profile of Prasugrel.
Prasugrel, a third-generation thienopyridine antiplatelet agent, demonstrated superior efficacy to clopidogrel but with an increased risk of bleeding in the phase III pivotal registration Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition with Prasugrel-Thrombolysis in Myocardial Infarction (TRITON-TIMI 38). This article reviews and discusses select components of
Labor Market Opportunities and Women’s Decision Making Power within Households
Despite the perceived importance of labor market opportunities in shaping married women’s outside option, and their bargaining power within households as a result, this link has received very little empirical attention. Using longitudinal data on who makes the decision on a wide range of issues within Mexican households and data from the administrative records of the Mexican Social Security Instit
Prehospital Coagulation Monitoring of Resuscitation With Point-of-Care Devices.
A variety of Point-Of-Care monitors for the measurement of hematocrit, hemoglobin, blood gas with electrolytes and lactate can be used also in the prehospital setting for optimizing and individualizing trauma resucitation. Point-Of-Care coagulation testing with activated prothrombin test, prothrombin test and activated coagulation/clotting time tests are available for prehospital use. Although rob