Background: One-pot multi-step biocatalysis is advantageous over step-by-step synthesis as it reduces the number of process operation units, leading to significant process intensification. Whole-cell biocatalysis with metabolically active cells is especially valuable since all enzymes can be co-expressed in the cell whose metabolism can be exploited for supply of co-substrates and co-factors. Resu

HER2 is a well-established prognostic and predictive factor in invasive breast cancer. The role of HER2 in ductal breast carcinoma in situ (DCIS) is debated and recent data have suggested that HER2 is mainly related to in situ recurrences. Our aim was to study HER2 as a prognostic factor in a large population based cohort of DCIS with long-term follow-up.

Seed-eating Apion weevils (Coleoptera: Apionidae) cause large economic losses in white and red clover seed production across Europe. Monitoring and control of clover weevils would be facilitated by semiochemical-based methods. Until now, however, nothing was known about physiological or behavioral responses to semiochemicals in this insect group. Here we analyzed the antenna of the white clover (T

The purpose of this study was to develop multimodality SPECT/MRI contrast agents for sentinel lymph node (SLN) mapping in vivo. METHODS: Nanoparticles with a solid iron oxide core and a polyethylene glycol coating were labeled with (99m)Tc. The labeling efficiency was determined with instant thin-layer chromatography and magnetic separation. The stability of the radiolabeled superparamagnetic iron

Abstract in UndeterminedThis article considers the paintings of the contemporary American artist Josh Keyes from an ecocritical point of view and discusses the importance of biocentrism and the affinity between humans and nature in the artist’s work.

This book is the outcome of the International Symposium on Clause Linking in Semitic Languages, Kivik, Sweden, 5-7 August 2012. A strong incentive for the symposium was the renewed interest, in recent years, in the nature of non-main clause linking. Current research has brought into focus the concept of a main line and digressions from the main line in various discourse types. The conference invit

Double-sided three-dimensional porous silicon chips, 6 mm x 6 mm, covered with a 40 nm gold (nano)layer, were fabricated from a porous silicon wafer. Scanning electron microscopy along with electrochemical characterisation showed sample conductivity, mechanical stability, and high surface area of the thus fabricated devices, viz. 10 times higher electrochemically active surface area compared to th

The dynamic nature of human working memory, the general-purpose system for processing continuous input, while keeping no longer externally available information active in the background, is well captured in immediate free recall of supraspan word-lists. Free recall tasks produce several benchmark memory phenomena, like the U-shaped serial position curve, reflecting enhanced memory for early and la

Objective/Background: Reports on heart failure (HF) predictors are scarce. We assessed gender-specific HF predictors. Design: Preventive case-finding programme, register study. Setting: City population-based sample. Methods: We examined 33,342 HF-free subjects, 32.7% women, included in Malmo Preventive Project. Mean inclusion age was 49.7±7.4 years for women and 43.7±6.6 years for men. Results

A model for the third order optical response of carotenoids is used to analyse transient grating and pump-probe data of peridinin in solution and bound in the peridinin-chlorophyll protein (PCP). For peridinin in solution, the transient grating signal detected at 505 nm exhibits a bi-exponential recovery whose fast phase is assigned to relaxation from the S-2 state that has a lifetime of 75 +/- 25

Popular Abstract in Swedish När det blir stopp i ett av hjärtats kranskärl blockeras blodflödet till hjärtat, vilket kan orsaka blodbrist i en del av hjärtmuskeln. Detta kan i sin tur leda till hjärtinfarkt, vilket tar död på hjärtmuskelceller och skadar hjärtat. Vid den efterföljande behandlingen av hjärtinfarkt kan små proppar i kranskärlen, så kallade mikroembolier, ytterligare förvärra skadan Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. Following an MI it is important to accurately determine the size of the infarction, as it can be used for guidance in terms of

Utifrån aktuell forskning kring publik och reception, och mot bakgrund av en förskjutning inom samtidens scenkonst mot åskådarnas delaktighet och medansvar söker texten uppvärdera publiken och de många aspekter av teaterhändelsen som receptionsperspektivet aktualiserar, och bidra till en omdefiniering av teaterns problem och dess uppdrag visavi publiken.

Very old persons (80+) are often described as "frail", implying that they are particularly vulnerable to adverse health outcomes. Elderly Persons in the Risk Zone was designed to determine whether a preventive home visit or multiprofessional senior group meetings could postpone deterioration in frailty if the intervention is carried out when the person is not so frail.

Bornholm is a Danish island almost in the center of the southern Baltic Sea. The strategic location of the island, its rich archeology, and its complex geology make it an intriguing location for the isotopic study of past human mobility. The focus of this study is on the large cemetery of Ndr. Grødbygård in the southern part of the island, which dates to the eleventh century AD and contains 553 in