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Molecular Mechanism of Growth Hormone - Involvement of Janus Kinase 2, Insulin Receptor Substrate-1 and -2 and Phosphatidylinositol 3-Kinase In the Acute Insulin-Like Effects of Growth Hormone In Primary Rat Adipocytes

Popular Abstract in Swedish Kroppens viktigaste hormon för längdtillväxt har följdriktigt kallats tillväxthormon (GH efter engelskans growth hormone). GH produceras i hypofysen som är en liten körtel belägen på hjärnans undersida, och utsöndras härifrån till blodbanan och når på så sätt kroppens olika organ, vävnader och celler. Vikten av normal tillförsel av GH illustreras av att överskott på GH Originally studying the molecular mechanisms for the insulin-like effects of growth hormone (GH), lipogenesis and antilipolysis, in isolated rat adipocytes we found that the GH receptor (GHR) was tyrosine phosphorylated in response to GH in cells that were responsive to these effects. Then, as Janus kinase 2 (JAK2) was described as a GH-stimulated and GHR-associated tyrosine kinase, we found that

Multiuser detection for interference-limited MIMO systems

We consider the application of multiuser detection to the downlink of interference-limited multiple-input multiple-output (MIMO) cellular systems. MIMO systems have been shown to yield a tremendous capacity for a single link with white Gaussian noise. In a cellular environment, there will often be co-channel interference from other cells, which becomes the dominating channel impairment. Here space

Mechanisms controlling striatal projection neurone generation, from patterning to early differentiation

Popular Abstract in Swedish Detta arbete handlar om utvecklingsneurobiologi. Ett långt ord men så beskriver det också precis vad det rör sig om: biologiska studier rörande nervsystemets utveckling. Generellt sett kan man säga att utvecklings-neurobiologisk forskning på lång sikt syftar till att förstå nervsystemets utveckling såpass väl att man skall kunna använda denna kunskap för att reparera etThe striatum is part of the telencephalon, the most anterior part of the vertebrate brain. From when it first can be identified, telencephalic morphology is highly complex and a wide range of mechanisms has been suggested to participate in its induction, patterning and neurogenesis. Sonic hedgehog (shh), a gene coding for a secreted protein has been suggested to be required for ventral telencephal

Praktisk byggnadsfysik

Ämnesområdet byggnadsfysik innefattar traditionellt kunskaper om hur man utformar byggnadsdelar och anslutningar mellan byggnadsdelar för att klara kraven på värmeisolering, fuktsäkerhet och lufttäthet. I denna bok behandlas främst de värme- och fukttekniska kraven. Boken inleds med en beskrivning av ett antal skadefall eller problem som har en byggnadsfysikalisk förklaring. Härefter följer en re

The hybridized M3d-F2p character of low-energy unoccupied electron states in 3d metal fluorides observed by F 1s absorption

The near-edge fine structure of the F 1s absorption spectra of 3d metal fluorides was studied for the first time with high energy resolution. The spectra of these, the most ionic compounds of the 3d atoms, are analyzed comparing with the F 1s absorption spectrum of the molecular TiF62− anion in solid K2TiF6. The latter spectrum was afore interpreted considering the fluorine spectra of the molecula

Pietism and Community in Magnus Friedrich Roos's Dialogue Books

The emphasis on the equal and eternal responsibility of subjects of different gender and social positions in M.F. Roos's dialogue books promoted a special combination of radical equality in anthropology and a conservative understanding of society. A Pietist teaching on salvation permeates the Orthodox principles on vocation in such a way, that the vocation to community life as a Christian farmer,

Milk Folates: Characterisation and Availability

With the ultimate goal to study milk folate bioavailability, a reverse-phase HPLC technique was developed and compared with a radioprotein binding assay. All methods showed similar ranges for folates in cow’s milk, with the variation attributed to seasonal variations and the use of different starter cultures. Most cheese varieties contained slightly higher values for whey cream cheese. Studies usi

Some strategic national initiatives for the Swedish education in the geodata field

This paper describes national cooperation in Sweden launched by its universities and authorities, aimed at improving geodata education. These initiatives have been focused upon providing common access to geodata, the production of teaching materials in Swedish and organizing annual meetings for teachers. We argue that this type of cooperation is vital to providing high quality education for a poor

Distribution of Pharmaceuticals - B2C Concept

Increased use of the Internet has created new business opportunities and market channels. The pharmacy retail sector is using e-commerce to sell pharmaceuticals. In the USA over 400 different pharmacies were selling products to their customers and offering home delivery in the year 2000. The Swedish pharmaceutical industry has seen e-commerce as a new market channel and is introducing contact cent

Människa och miljö. Om attityder, värderingar, livsstil och livsform

Många människor i dagens samhälle har kunskap om en rad miljöproblem. De vet också hur miljöproblem hänger samman med mänskliga beteenden och handlingsmönster. Många känner oro för framtiden och en hel del uttrycker detta offentligt genom demonstrationer, protester i massmedia eller i samtal man och man emellan. Ändå går de allra flesta förändringar i konsumtionsmönster, handlingsmönster och livss