BackgroundBiological heterogeneity of large B cell lymphomas (LBCLs) is poorly captured by current prognostic tools, hampering optimal treatment decisions.MethodsWe dissected the levels of 1,463 serum proteins in a uniformly treated trial cohort of 109 patients with high-risk primary LBCL (ClinicalTrials.gov: NCT01325194) and correlated the profiles with molecular data from tumor tissue and circul

Objectives: Dyspnea, or breathlessness, is a frequent and distressing symptom among patients with heart and lung diseases, particularly in advanced cancer stages, where it affects up to 90% of lung cancer cases. This symptom considerably diminishes quality of life, leading to physical deconditioning, increased levels of anxiety and depression, repeated hospitalizations, and elevated mortality rate

Background/objectives: Mycosis fungoides (MF) is a rare malignancy, with an indolent course in the early stages of the disease. However, due to major molecular and clinical heterogeneity, patients at an advanced stage of the disease have variable responses to treatment and considerably reduced life expectancy. Today, there is a lack of specific markers for the progression from early to advanced st

Accurately representing and predicting hydrological processes in terrestrial ecosystems is crucial for understanding the impacts of global environmental change, particularly climate change. This doctoral thesis aims to advance the understanding of vegetation-hydrology interactions and provides new modelling approaches to enhance hydrological prediction abilities. The thesis is grounded in the eval

BACKGROUND: While the associations between pediatric non-obese metabolic dysfunction-associated fatty liver disease (MAFLD) and multiple diagnostic biomarkers are well-established, the role of a broader range of blood-based, urine-based, and body composition-based biomarkers for monitoring MAFLD are needed.METHODS: A pediatric cohort was established in Wuxi, China. We measured body composition bio

BackgroundIn the last three decades, the increasing trend in female employment in Bangladesh has been critically analyzed from a socioeconomic point of view; however, its impact on infant and young child feeding (IYCF) practices has yet to be systematically reviewed. The aim of this systematic review and meta-analysis is to investigate the association between these variables.MethodsA systematic li

This article investigates changes in the right to social assistance – a means-tested cash support programme, regulated by the Social Services Act – for irregularised migrants over a period of four decades, 1982–2022. The article makes the case that austerity policies have hollowed out the right to support, with significant repercussions for those with irregularised residency status. In doing so, i

This study investigates building of trust between service providers and consumers on peer-to-peer tourist accommodation platforms by focusing on their affordances. Trust is necessary for peer-to-peer exchanges to happen. Platforms, as technological intermediaries afford specific actions that can result in trust, for example mutual consumer-provider reviews. Use of the same measures may imply suspi

This edited work draws on a range of contributed expertise to trace the fortune of an Aristotelian thesis over different periods in the history of philosophy. It presents eight cases of direct or indirect challenges to the Aristotelian passive account of human cognition, taking the reader from late antiquity to the 20th century. Chapters analyse the (often indirect) effect of Aristotle’s account o

The aim of this article is to show that at the end of the 13th century there’s a change of approach to the sophistical syllogism, going from a definition based on its formal features to a definition based on its pragmatic features. The first position is put forward by Simon of Faversham, during the 1280s, probably during his stay in Paris. The second position is put forward by Radulphus Brito, the

This paper analyses John Buridan’s approach to the notion of syllogism by putting it in the institutional and doctrinal contexts where he belongs, that is, the faculty of arts of the University of Paris and its Aristotelian logical tradition. The analysis aims to ascertain Buridan’s innovative contribution to the history of logic by underscoring the points of continuation and rupture with respect

Aristotle puts forward claims about truth in a number of places of his phil-osophical output, in works of logical, psychologico-epistemological andmetaphysical character. In these works, truth seems to be susceptible of at-tribution to thoughts, language, and things, but the modalities of these attri-butions remain unclear, as it is unclear whether these attributions are relatedto each other, and

Discussions about singular cognition, and its linguistic counterpart, are by no means exclusive to contemporary philosophy. In fact, a strikingly similar discussion, to which several medieval texts bear witness, took place in the late Middle Ages. The aim of this article is to partly reconstruct this medieval discussion, as it took place in Parisian question-commentaries on Aristotle's De anima, s