The aim was to investigate how patients in a clinical setting, combining acute stroke care and rehabilitation, perceived the value and meaning attached to a commonly used instrumental occupation, namely "Brewing coffee and making an open-face cheese sandwich with sliced vegetable". Another aim was to validate the ValMO model, proposing that value and meaning are related phenomena. Upon performing

This study analyzes innovation activities in medium-technology sectors in Germany, Italy and Spain and checks whether cross-country similarities or differences prevail. The results have important implications for the Sectoral Systems of Innovation and the Distance-to-the-Frontier frameworks. While the Sectoral Systems of Innovation predicts the existence of technology-related similarities in innov

Background: Proteases of human pathogens are becoming increasingly important drug targets, hence it is necessary to understand their substrate specificity and to interpret this knowledge in practically useful ways. New methods are being developed that produce large amounts of cleavage information for individual proteases and some have been applied to extract cleavage rules from data. However, the

Dual-broadband rotational coherent anti-Stokes Raman spectroscopy (DB-RCARS) has been investigated for thermometry under high-pressure and high-temperature conditions, in the product gas of fuel-lean hydrocarbon flames up to 1 MPa. Initial calibration measurements made in nitrogen, oxygen, and air, at pressures up to 1.55 MPa and temperatures up to 1800 K, showed good agreement between experimenta

On 23rd November 2009, during the early commissioning of the CERN Large Hadron Collider (LHC), two counter-rotating proton bunches were circulated for the first time concurrently in the machine, at the LHC injection energy of 450 GeV per beam. Although the proton intensity was very low, with only one pilot bunch per beam, and no systematic attempt was made to optimize the collision optics, all LHC

Popular Abstract in Swedish Varje år drabbas cirka 8000 svenska kvinnor av bröstcancer, och antalet nyinsjuknade ökar årligen med någon procent. I Sverige idag finns fler än 90 000 kvinnor som har avslutat eller är under behandling för sjukdomen. Med hjälp av nya återfallsförebyggande läkemedel har prognosen kraftigt förbättrats och 5-årsöverlevnaden är nästan 90 %. Den stora utmaningen i dagens bOne of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv

Fix any n≥1. Let X~1,…,X~n be independent random variables. For each 1≤j≤n, X~j is transformed in a canonical manner into a random variable Xj. The Xj inherit independence from the X~j. Let sy and s∗y denote the upper 1y th −−− quantile of Sn=∑nj=1Xj and S∗n=sup1≤k≤nSk, respectively. We construct a computable quantity Q−−y based on the marginal distributions of X1,…,Xn to produce upper and lower b

Walkability is often researched from the perspective of certain physical features in the built environment. However, for this paper, the point of departure was to also treat walking as a transport mode for reaching destinations and performing every-day activities. A conceptual model addressing both perceptions of the built environment and perceived limits due to every-day activities was used as a

Background: Xylose reductase (XR) and xylitol dehydrogenase (XDH) from Pichia stipitis are the two enzymes most commonly used in recombinant Saccharomyces cerevisiae strains engineered for xylose utilization. The availability of NAD+ for XDH is limited during anaerobic xylose fermentation because of the preference of XR for NADPH. This in turn results in xylitol formation and reduced ethanol yield

Prehistoric population structure associated with the transition to an agricultural lifestyle in Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone Age human remains suggest that hunter-gatherers had lower genetic diversity than that of farmers. Despite their close geographical proximity, the genetic differentiation between the two Stone Age groups was greater tha

Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, involving collaborative methodology using 'snapshot' clinical data collection over a 2-week period. The primary aim is to identify internationally relevant, modifiable surgical practices (in ter

The measurement of primary [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] production at mid-rapidity ([Formula: see text] 0.5) in proton-proton collisions at [Formula: see text][Formula: see text] 7 TeV performed with a large ion collider experiment at the large hadron collider (LHC) is reported. Particle identification is performed using the specific ionisat

Popular Abstract in Swedish Till och med kroppens allra enklaste celler är så avancerade att vi inte förstår i detalj hur de fungerar eller hur de påverkar kroppen. Nervceller tillhör kroppens mer avancerade celler och vi får erkänna att all den kunskap vi har om dem är mindre än vad som finns att veta. Komplexiteten hos hjärnan är mångfalt större för nervcellerna kommunicerar blixtsnabbt med varaIn the hippocampus, dendritic spines are compartmentalized postsynaptic micro-domains in the excitatory synapse. Subsets of bigger and mushroom-shaped hippocampal dendritic spines contain tubules and cisterns of endoplasmic reticulum (ER) that are connected to the soma and dendrites of the neuron. These ER containing spines differ in their ability to retain ER. We hypothesized a functional couplin