CK2 is an extremely pleiotropic Ser/Thr protein kinase, responsible for the generation of a large proportion of the human phosphoproteome and implicated in a wide variety of biological functions. CK2 plays a global role as an anti-apoptotic agent, a property which is believed to partially account for the addiction of many cancer cells to high CK2 levels. To gain information about the CK2 targets w

The Swedish classroom of today displays linguistic, cultural, and social diversity. Hence, if a teacher is to be able to assist each pupil in a language development regarding the elaborated language as well as the private, a new kind of work with language care and deeper knowledge of language norms are required. Furthermore, the elaborated language is consistently changing as a result of the logic

Effects of peptide hydrophobicity on lipid membrane binding, incorporation, and defect formation was investigated for variants of the complement-derived antimicrobial peptide CNY21 (CNYITELRRQHARASHLGLAR), in anionic 1-palmitoyl-2-oleoylphosphatidylethanolamine (POPE)/1-palmitoyl-2-oleoylphosphatidylglycerol (POPG) and zwitterionic 1-palmitoyl-2-oleoylphosphatidylcholine (POPC) membranes. Using a

Pre-crystalline graded rings constitute a class of rings which share many properties with classical crossed products. Given a pre-crystalline graded ring A, we describe its center, the commutant C-A(A(0)) of the degree zero grading part, and investigate the connection between maximal commutativity of A(0) in A and the way in which two-sided ideals intersect A(0).

This thesis presents the results of an investigation into BIM standardisation needs and procedural supporting mechanisms that may enable design, construction and operating (DCO) organisations to advance their deployment of Building Information Modelling (BIM) technology, and improve construction project outcomes. To achieve sustainable development requires effective information management. Buildi

Background: The major histocompatibility complex (MHC) is an important component of the vertebrate immune system and is frequently used to characterise adaptive variation in wild populations due to its co-evolution with pathogens. Passerine birds have an exceptionally diverse MHC with multiple gene copies and large numbers of alleles compared to other avian taxa. The Nesospiza bunting species comp

Objective To determine the ability of acoustic streaming to discriminate between endometriomas and other adnexal masses. Methods We used data from 1938 patients with an adnexal mass included in Phase 2 of the International Ovarian Tumor Analysis (IOTA) study. All patients had been examined by transvaginal gray-scale and Doppler ultrasound following a standardized research protocol. Assessment of a

Abstract Objective. Severity of acute pancreatitis (AP) can vary from a mild to a fulminant disease with high morbidity and mortality. Cost analysis has, however, hitherto been sparse. The aim of this study was to calculate the cost of acute pancreatitis, both including hospital costs and costs due to loss of production. Material and methods. All adult patients treated at Skane University Hospital

As health care systems worldwide struggle with rising costs, a consensus is emerging to refocus reform efforts on value, as determined by the evaluation of patient outcomes relative to costs. One method of using outcome data to improve health care value is the disease registry. An international study of thirteen registries in five countries (Australia, Denmark, Sweden, the United Kingdom, and the

This paper describes the concept, technical realisation and validation of a largely data-driven method to model events with Z -> tau tau decays. In Z -> mu mu events selected from proton-proton collision data recorded at root s = 8 TeV with the ATLAS experiment at the LHC in 2012, the Z decay muons are replaced by tau leptons from simulated Z -> tau tau decays at the level of reconstructed tracks

Abstract in UndeterminedParticipatory media are commonly used in today's society for a variety of purposes. The credibility associated with these media is sometimes contested, and their acceptance into school practices has been debated. Focus group interviews with teachers and librarians in upper secondary schools in Sweden are used to investigate conceptions and experiences of activities involvin

The European X-Ray Free Electron Laser (XFEL), the research facility currently under construction in the Hamburg area, Germany, is based on a superconducting linear accelerator that brings electrons to almost the speed of light. The linear accelerator consists of 100 accelerating cryomodules (CMs) operating at the temperature of 2 K. The thermal performances of the accelerator CMs are a key elemen

Background and Objectives. The pathogenesis of otitis media (OM) involves a number of factors related to the anatomy, pathology, and cell biology of the middle ear, the mastoid, the Eustachian tube, and the nasopharynx. Although some issues of pathogenesis are fairly well established, others are only marginally indicated by current knowledge, and yet others remain undisclosed. The objective of thi

Where does linguistic structure come from? Recent gesture elicitation studies have indicated that constituent order (corresponding to for instance subject - verb - object, or SVO in English) may be heavily influenced by human cognitive biases constraining gesture production and transmission. Here we explore the alternative hypothesis that syntactic patterns are motivated by multiple environmental

European Union financed Interreg programmes focusing on cross-border region building form an important part of the EU integration policy. The region building processes involve many fields of action in which destination development is one. In this article, the latest finished programme, Interreg III, will be highlighted with special focus on cross-border regions in the Baltic Sea Area. The purpose

This report gives a short introduction and overview of the research project conducted during the construction of the Limnologen-project in Växjö, Sweden. This multi-storey residential housing project has been documented in a number of sub-projects (vibrations and acoustics, sway, long term deformation, temperature and relative humidity in the structure, environmental impact of timber construction,

Postoperative bacterial infections are common despite prophylactic administration of antibiotics. The wide-spread use of antibiotics in patients has contributed to the emergence of multiresistant bacteria. A restricted use of antibiotics must be followed in most clinical situations. In surgical patients there are several reasons for an altered microbial flora in the gut in combination with an alte

Popular Abstract in Swedish Ett gemensamt drag i befintlig forskning är att språkliga delar av gymnasieskolans svenskämne framstår som diffusa och tycks sakna kärna och teoretisk ram. Syftet med avhandlingen På jakt efter språk är att beskriva och problematisera språkdelen i gymnasieskolans svenskämne. Undersökningen är gjord i två klasser på studieförberedande program under deras första termin i A common feature of existing research is that the linguistic part of the subject Swedish in upper secondary school appears to be diffuse and seems to lack core and theoretical framework. The purpose of the thesis ’Hunting for language’ is to describe and investigate how the linguistic part of Swedish is handled in upper secondary school. The study was carried out in two classes of college-preparat