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PURPOSE: The aim of the study was to determine the perimetric rate of glaucoma progression in the ongoing Glaucoma Intensive Treatment Study (GITS) after 3 years of follow-up.DESIGN: This is a randomized, two-centre, prospective open-labelled treatment trial for open-angle glaucoma (OAG).PARTICIPANTS: The participants of this study were treatment-naive patients with newly diagnosed OAG, aged 46-78

Ambient temperature strongly determines the behaviour, physiology, and life history of all organisms. The technical assessment of organismal thermal niches in form of now so-called thermal performance curves (TPC) thus has a long tradition in biological research. Nevertheless, several traits do not display the idealized, intuitive dome-shaped TPC, and in practice assessments often do not cover the

Hemoglobin-based oxygen carriers have long been pursued to meet clinical needs by using native hemoglobin (Hb) from human or animal blood, or recombinantly produced Hb, but the development has been impeded by safety and toxicity issues. Herewith we report the successful production of human fetal hemoglobin (HbF) in Nicotiana benthamiana through Agrobacterium tumefaciens-mediated transient expressi

Background/Aim: To evaluate quality of life (QoL) in women treated for ovarian tumors one year after laparotomy. Patients and Methods: The validated quality of life questionnaires (EORTC QLQ-C30 and QLQ-OV28) were sent to women who had undergone laparotomy due to ovarian tumors 12 months after surgery. The answers were analyzed and grouped according to the ovarian tumor histology (benign, borderli

Background: Reports on possible benefits for continence with nerve-sparing (NS) radical prostatectomy have expanded the indications beyond preservation of erectile function. It is unclear whether NS surgery affects oncological outcomes. Objective: To determine whether the degree of NS during radical prostatectomy influences oncological outcomes. Design, setting, and participants: Of 4003 patients

In traditional molecular imprinting reactions, the initial radicals generated by thermo- or photo-decomposition are randomly distributed in the reaction mixture. Because a noticeable portion of the initial radicals is able to cause self-polymerization of the crosslinking monomer, a significant part of the polymer product does not contain successfully imprinted molecular recognition sites. To solve

This paper considers an autoregressive panel data model in which the autoregressive coefficient has undergone a structural break. The object of interest is the unknown breakpoint. A least squares-based estimator is proposed that is shown to be consistent when only the number of cross-section units, N, is large and the number of time periods, T, is small, thereby enabling quick detection of the ons

Lactic acid fermentation offers a processing alternative for preservation of watermelon juice, which is sensitive to heat, oxygen, and light. In this study, 8.8 × 107 CFU/mL of Lactobacillus plantarum DSM 9843 in MRS broth was inoculated in 9.9 mL of sterilized watermelon juice. Nanosecond-pulsed electric field was applied during the log growth phase of the bacteria. An 19% increase in L-lactic ac

The emergence of pottery in Europe is associated with two distinct traditions: hunter-gatherers in the east of the continent during the early 6th millennium BC and early agricultural communities in the south-west in the late 7th millennium BC. Here we investigate the function of pottery from the site of Rakushechny Yar, located at the Southern fringe of Eastern Europe, in this putative contact zon

Will the appeal of the Western-led global democratic order triumph over China’s pragmatic approach to infrastructure investments? In this op-ed, PhD student Tabita Rosendal Ebbesen, Lund University, explores the possibility that the two new infrastructure investment initiatives proposed by the US and EU might pose a challenge to China’s Belt and Road Initiative (BRI).

The Atlantic Walrus: Multidisciplinary insights into human-animal interactions addresses the key dimensions of long-term human walrus interactions across the Atlantic Arctic and subarctic regions, over the past millennia. This book brings together research from across the social and natural sciences to explore walrus biology, human culture, environmental conditions and their reciprocal effects. To

A method for risk analysis and building performance simulations is developed to optimise the building design process and fulfil the design criteria. The aim is to support the decision-makers during the building design process by including uncertainties from the design phase, quantifying the probability of attaining the energy performance criteria and financial requirements. The method is meant to

Due to the marine reservoir effect, radiocarbon dates of marine samples require a correction. Marine reservoir effects, however, may vary amongdifferent marine species within a given body of water. Factors such as diet, feeding depth and migratory behaviour all affect the 14C date of a marineorganism. Moreover, there is often significant variation within single marine species. Whilst the careful c

In the present study the thermo-hydraulic characteristics of geyser in the cryogenic fuel transportation pipe of a liquid rocket is experimentally investigated using liquid nitrogen. The typical thermo-hydraulic appearances are characterized and analyzed in the geyser process to effectively recognize the occurrence of geyser in practical engineering. The effect of interfering factors such as heat

Byggnaders energieffektivitet är ett fokusområde i arbetet med att minska klimatförändringarna, då byggnader står för cirka 40 procent av den totala energianvändningen i Europeiska unionen. En lösning som tillämpas för att minska byggnaders energibehov är att ständigt införa strängare byggregler. Följaktligen ökar betydelsen av precisa och effektiva simuleringar för att kunna beräkna byggnaders frAs most countries worldwide continue to mitigate climate change, one area of focus is a building's energy efficiency. Buildings currently account for approximately 40 per cent of the total energy use in the European Union. One solution for reducing the energy demand from buildings is by continually implementing more stringent building regulations. Consequently, the importance of accurate and effic

Archaeological radiocarbon dating in coastal northern Hokkaido is challenged by the marine reservoir effect and the scarcity of materials with terrestrial carbon sources. This has contributed to gaps and general uncertainty in the timing of the region's culture-historical periods. The Late Holocene site of Hamanaka 2 on Rebun Island, featuring a stratified shell midden context with excellent prese

Data paper. How are particular material culture traditions passed from one generation to the next? This digital archive supports "Technology as Human Social Tradition: Cultural Transmission among Hunter-Gatherers" (Jordan 2015) published by University of California Press. The archive consists of 15 Excel files which were used to conduct in-depth analysis of the factors driving diversity and change

Determining the proportion of males and females in zooarchaeological assemblages can be used to reconstruct the diversity and severity of past anthropogenic impacts on animal populations, and can also provide valuable biological insights into past animal life-histories, behaviour and demography, including the effects of environmental change. However, such inferences have often not been possible du

We explore peoples' dispositions and practices with regard to social–ecological transformations based on a sustainable welfare policy strategy in Sweden. We draw on Bourdieu's concept of habitus to highlight the relations between social positions, dispositions, and position-takings. Using data from an own survey, we identify habitus types and place these in the space of social positions. We apply