Although cancer is a heterogeneous disease, a common theme in tumor cells is the deregulation of cell division, which renders tumor progression independent of otherwise necessary internal or external growth cues. This may provide cancer cells with the ability to divide indefinitely, posing a threat to the rest of the organism. As the tumor grows, nearby healthy tissues are harmed, which eventually

Semiconductor nanowires have attracted considerable attention during the last decade and are considered as an alternative path to extend the road for scaled semiconductor devices. The interest is motivated by the improved electrostatic control in the cylindrical geometry and the possibility to utilize heterostructures in transistor design. Currently, nanowire transistors have been realized both in

The North Atlantic Oscillation (NAO), a measure of the strength of the zonal wind across the North Atlantic Ocean, strongly influences weather conditions in NW Europe, e.g. temperature, precipitation and wind, especially during winter. It was hypothesised that elevated concentrations of nitrogen oxides in Gothenburg would be enhanced during negative NAO index (NAOI) conditions, representing more a

To identify susceptibility loci for classical Hodgkin's lymphoma (cHL), we conducted a genome-wide association study of 589 individuals with cHL (cases) and 5,199 controls with validation in four independent samples totaling 2,057 cases and 3,416 controls. We identified three new susceptibility loci at 2p16.1 (rs1432295, REL, odds ratio (OR) = 1.22, combined P = 1.91 x 10(-8)), 8q24.21 (rs2019960,

We use monodisperse poly(N-isopropylacrylamide) (PNIPAM) microgels as a model system for soft repulsive colloids and study their density dependent structural ordering and phase behaviour using confocal laser scanning microscopy (CLSM). The experiments are carried out at low temperatures, where the particles are in the swollen state and interact via a Hertzian potential, evidenced through a quantit

Popular Abstract in Swedish Intresset för utmattning har ökat både i Sverige och internationellt under de senaste årtiondena. Utmattning som begrepp är oklart definierat vetenskapligt, och det finns olika benämningar på utmattningstillstånd, som till exempel den något gammalmodiga benämningen neurasteni, som ännu finns kvar som diagnos-klassifikation (där även benämnt ”trötthetssyndrom”), kronisktThe interest in exhaustion has increased rapidly during the last few decades in many developed countries. In Sweden, prevalence of exhaustion increased by 50 percent on average between 1989 and 2005, and recent data reveals that exhaustion still remains at this higher level. Scientifically, exhaustion is not clearly defined. Chronic stress is acknowledged to give rise to exhaustion, but specific m

In the coming years, it is anticipated that if we continue with the same pace of energy consumption, communities will continue to face three major challenges; a mounting increase in energy demands, pollution, and global warming. On a local scale, Egypt is experiencing one of its most serious energy crises in decades. The energy consumed in indoor cooling and heating is the biggest portion of total

The production of pi(+), pi(-), K+, K-, p, and (p) over bar at mid-rapidity has been measured in proton-proton collisions at root s = 900 GeV with the ALICE detector. Particle identification is performed using the specific energy loss in the inner tracking silicon detector and the time projection chamber. In addition, time-of-flight information is used to identify hadrons at higher momenta. Finall

The article is a survey of how farming and forestry is depicted in art in Sweden during the 19th century. The author discusses what is depicted, as well as how and why. A focus question in the article is the relative abscence of farming and forestry as a motif on the Swedish art scene during the period.

In his paper Hypnosis Reconsidered, Resituated, and Redefined (JSE 26(2):297–327), Adam Crabtree, a distinguished expert in the history of hypnosis, maintains that contemporary hypnosis research suffers from conceptual disorder. In his words, he attempts to redefi ne hypnosis in order to provide a stronger ground for future research. We find that his proposed reconsideration of hypnosis as a form

The female athlete triad (Triad), links low energy availability (EA), with menstrual dysfunction (MD), and impaired bone health. The aims of this study were to examine associations between EA/MD and energy metabolism and the prevalence of Triad-associated conditions in endurance athletes. Forty women [26.2 +/- 5.5 years, body mass index (BMI) 20.6 +/- 2.0 kg/m(2), body fat 20.0 +/- 3.0%], exercisi

Sturgeon populations in the Danube River have experienced severe decline during the last several decades, mostly due to the poorly regulated fishery, river fragmentation and water pollution. This study focuses on gaining better understanding of sturgeon life history primarily by addressing the assessment of microelement accumulation in sturgeon pectoral fin rays, especially of strontium and calciu

Ternary semiconductor nanowire arrays enable scalable fabrication of nano-optoelectronic devices with tunable bandgap. However, the lack of insight into the effects of the incorporation of Vy element results in lack of control on the growth of ternary III-V1-yVy nanowires and hinders the development of high-performance nanowire devices based on such ternaries. Here, we report on the origins of Sb-

Recent years have seen an increasing attention given to wireless Personal Area Networks (PANs), which are typically networks with small transmitter-receiver (TX-RX) separation. The desire for high data rates has led to an interest in deploying multiple-input multiple-output (MIMO) transmission for such systems, but up until this date there exists, to the authors’ best knowledge, no MIMO channel mo

We present a novel scheme for high-order harmonic generation, enabling the production of spatially separated isolated attosecond pulses. This can be achieved by driving the generation process with two identical, but temporally delayed laser pulses, which are noncollinearly overlapping in the generation medium. Our approach provides intense attosecond pulses directly separated from the fundamental

The primary aim of the article is to examine the sum of the three Swedish judgments of 2013 that was handed down after the ECJ's judgment in the Åkerberg Fransson-case. The examination is done against the backdrop of the legal developments preceding these judgments, with a particular attention to how different layers of law are perceived and given effect in the national legal order.

The aim was to assess the environmental sustainability of sugar beet transport in Scania, Sweden—estimating lorry travel distances, fuel use and air emissions. Scenario analyses measuring the same parameters for switching to newer vehicle types and differing ratios of biodiesel were also performed. The method applied for distance calculations was a GIS-based proximity analysis. Results revealed th