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BACKGROUND: The OVHIPEC-1 trial previously showed that the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery resulted in improved progression-free and overall survival compared with cytoreductive surgery alone at 4·7 years of follow-up in patients with stage III epithelial ovarian cancer who were ineligible for primary cytoreduction. We report the fina

ObjectiveTo evaluate the ACR/EULAR 2022 criteria for ANCA-associated vasculitides (AAV) classification and compare them with the European Medicines Agency (EMA) algorithm and with classification based only on ANCA serology.MethodsIn the analysis, 374 cases (47% female) were classified according to the EMA algorithm, ANCA serology and ACR/EULAR criteria. The agreement rate was calculated using the

We explore the relations among institutional quality, households’ level of trust, and stock market participation. We find that institutional quality has a significant impact on both trust and participation. The individual level of trust significantly affects participation, but trust plays a small role in the effect of institutional quality on participation. Further, we demonstrate that immigrants

Background: Known risk alleles for epithelial ovarian cancer (EOC) account for approximately 40% of the heritability for EOC. Copy number variants (CNVs) have not been investigated as EOC risk alleles in a large population cohort. Methods: Single nucleotide polymorphism array data from 13071 EOC cases and 17306 controls of White European ancestry were used to identify CNVs associated with EOC risk

This search, a type not previously performed at ATLAS, uses a comparison of the production cross sections for e+μ− and e−μ+ pairs to constrain physics processes beyond the Standard Model. It uses 139fb−1 of proton–proton collision data recorded at s=13 TeV at the LHC. Targeting sources of new physics which prefer final states containing e+μ− to e−μ+, the search contains two broad signal regions wh

Recycling polymers by site-specific scission into short-chain oligomers/polymers, followed by recoupling these to form the original polymer presents an energetically more favorable shorter-loop chemical recycling in comparison to recycling into monomers. Here, we present the synthesis and polymerization of triaromatic diesters to prepare polyesters with acylhydrazone units as weak structural links

Utilizing building blocks derived from lignocellulose is an attractive strategy towards biobased aromatic polyesters. Here, we present the straightforward synthesis of three new asymmetric di-aromatic diester monomers by one-step reactions of lignin-derived hydroxybenzoates (methyl paraben, methyl vanillate and methyl syringate, respectively) with potentially sugar-based methyl 5-chloromethyl-2-fu

Since the 1970s, environment and energy-related problems have moved to centre stage on many political, business and research agendas. The notion of sustainable development has emerged as the dominant global discourse to adapt societies and economies to novel modes of production and consumption in areas such as transport, energy, housing, agriculture and food. For such shifts, new technology and te

Business angels are a vital source of capital for innovative start-up firms. However, many potentially attractive investment opportunities are rejected during the angel's decision-making process. Information asymmetry, risk and distrust in the relationship between the investor and the entrepreneur result in investment barriers. The concept of proximity has been proposed as a conceptual foundation

This paper has two objectives: first, to estimate the size of informal venture capital market in Sweden, and second, to explore the heterogeneity of informal investing behaviour. Based on quantitative data on 278 informal venture capital investors and 422 investments, this paper provides an estimation of the size of the informal venture capital market in Sweden and an analysis of its structure by

Grounded in social exchange theory (SET) this paper presents research on non-collaborative behaviour among accommodation businesses within their spatial context. The study adopts semi-structured interviews of 14 co-located accommodation businesses in Christchurch, New Zealand. The findings reveal three categories of non-collaborative factors that influence business behaviour, namely (1) resource-b

For the class of de Branges-Rovnyak spaces H(b) of the unit disk D defined by extreme points b of the unit ball of H∞, we study the problem of approximation of a general function in H(b) by a function with an extension to the unit circle T of some degree of smoothness, for instance satisfying Hölder estimates or being differentiable. We will exhibit connections between this question and the theory

Background: Takotsubo syndrome (TS) is a life-threatening acute heart failure syndrome without any evidence-based treatment options. No treatment for TS has been examined in a randomized trial. Study design and objectives: BROKEN-SWEDEHEART is a multicenter, randomized, open-label, registry-based 2 × 2 factorial clinical trial in patients with TS designed to test whether treatment with adenosine a