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Due to the large amount of accidents negatively affecting the wellbeing of the survivors and their families, a substantial amount of research is conducted to determine the causes of road accidents. This type of data come in the form of non-negative integers and may be modelled using the Poisson regression model. Unfortunately, the commonly used maximum likelihood estimator is unstable when the exp

This paper introduces Parameter Estimation by Raw Moments (PERM), a flexible method for evaluating a policy’s impact on the parameters of an outcome distribution. Such parameters include the variance (E[Y2]−E[Y]2), skewness and covariance of two outcomes. PERM simplifies distributional analysis by first separately estimating higher-order moment treatment effects (e.g., E[Y2]), then combining these

This paper examines seasonal migrant farmworkers in Turkey, focusing on the intersection of relations of production and social reproduction under rapidly shifting land and labour regimes. The workers are predominantly Kurds and Arabs of Turkey and Syrian refugees, and experience the intersecting crises of neoliberalism, rural-urban migration and conflict/disaster displacement in amplified ways. Wi

Accelerated deterioration of the constituting materials is important for the long-term performance of bridges or any other load-bearing structure with several-decades-long service life. In addition to the economic consequences due to increased maintenance and repair needs, severe deterioration can lead to catastrophic collapses with possible injuries, life losses, and impairments to infrastructure

This chapter explores the interrelationship between neoliberalism and economic inequality through a comparison of Denmark, Finland, Norway and Sweden, using Sweden as a main case and the other three major Nordic countries as comparative cases. The argument is that the relationship between neoliberalism and inequality isn’t a one-way street, but rather a question of mutual determination. NeoliberalThis chapter explores the interrelationship between neoliberalism and economic inequality through a comparison of Denmark, Finland, Norway and Sweden, using Sweden as a main case and the other three major Nordic countries as comparative cases. The argument is that the relationship between neoliberalism and inequality isn’t a one-way street, but rather a question of mutual determination. Neoliberal

Introduction: Elevated pulmonary vascular resistance (PVR) is observed in both physiological and pathological states. Pulmonary hypertension (PH) is a condition associated with significant morbidity and mortality in neonates and children and curative pharmacotherapy is lacking in most cases. In utero, a high PVR allows for blood to bypass the lungs through the open ductus arteriosus (DA). Vascular

Nitrous oxide (N2O) is the most important stratospheric ozone-depleting agent based on current emissions and the third largest contributor to increased net radiative forcing. Increases in atmospheric N2O have been attributed primarily to enhanced soil N2O emissions. Critically, contributions from soils in the Northern High Latitudes (NHL, >50°N) remain poorly quantified despite their exposure to r

Isolation and characterization of circulating tumor cells (CTCs) present a noninvasive alternative to monitor disease progression in individual patients. However, the heterogeneous lineage specificity of CTCs makes it difficult to isolate and identify possible CTCs by a liquid biopsy. Better label-free methods for the isolation of viable CTCs are needed. Our solution is a combined approach that is

Purpose: Small-bites suturing technique for laparotomy closure is now recommended as the standard of care. However, uptake of the practice remains slow. A medical technology called the SutureTOOL has been developed which can facilitate implementation of small-bites. The aim of the study was to compare the economic and clinical outcomes of laparotomy closure for patients using manual needle-driver

Galaxies are complex objects, yet the number of independent parameters to describe them remains unknown. We present here a non-parametric method to estimate the intrinsic dimensionality of large data sets. We apply it to wide-band photometric data drawn from the COSMOS2020 catalogue and a comparable mock catalogue from the HORIZON-AGN simulation. Our galaxy catalogues are limited in signal-to-nois

Soil aggregate stability has been asserted as an indicator of soil quality. Earthworms are essential for the stability of soil aggregates due to their activities, including burrowing and organic matter decomposition. In this study, we focused on how differences in plant litter quality influences earthworm abundance and composition and, subsequently, macroaggregate stability in an agroforestry ecos

DOPA Decarboxylase (DDC) has been proposed as a cerebrospinal fluid (CSF) biomarker with increased concentrations in Lewy body disorders (LBDs) and highest levels in patients receiving dopaminergic treatment. Here we evaluate plasma DDC, measured by proximity extension assay, and the effect of dopaminergic treatment in three independent LBD (with a focus on dementia with Lewy bodies (DLB) and Park

A series of rigid spiro-acetal-containing diol monomers derived from citric acid were synthesized and reacted with five different diisocyanates to form partially biobased thermoplastic polyurethanes (PUs) with different chemical and physical properties. The PUs had a renewable carbon content between 48 and 71%, and all formed transparent and colorless films with glass-transition temperatures betwe

The intersection of Tolkien’s writing and his environmental agenda have long been studied and the Ents are easily identified as one of the envoys of environmental messages in The Lord of the Rings. The Ents are anthropomorphic Hybrids in their function within the narrative, which can lead to a paradox when considering that ecocritical theories rather disapprove of humanising tools to convey ecolog

Objective: To investigate whether tangential versus segmental portomesenteric venous resection (PVR) impacts surgical and oncological outcome in patients undergoing pancreatoduodenectomy for pancreatic cancer with portomesenteric vein (PMV) involvement. Summary Background Data: Current comparative studies on tangential versus segmental PVR as part of pancreatoduodenectomy for pancreatic cancer inc

ER-positive/HER2-negative (ERpHER2n) breast cancer classified as PAM50 HER2-enriched (ERpHER2n-HER2E) represents a small high-risk patient subgroup. In this study, we investigate genomic, transcriptomic, and clinical features of ERpHER2n-HER2E breast tumors using two primary ERpHER2n cohorts comprising a total of 5640 patients. We show that ERpHER2n-HER2E tumors exhibit aggressive clinical feature

Triple-negative breast cancer (TNBC) is a clinically challenging and molecularly heterogenous breast cancer subgroup. Here, we investigate the DNA methylation landscape of TNBC. By analyzing tumor methylome profiles and accounting for the genomic context of CpG methylation, we divide TNBC into two epigenetic subtypes corresponding to a Basal and a non-Basal group, in which characteristic transcrip