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In a case-control study with 410 cases and 410 matched controls from the period 1980-1989 we investigated the role of occupations and occupational exposures as risk factors for squamous cell oral cancer. All subjects received a questionnaire. The response rates were 96% and 91% for cases and controls, respectively. A significantly increased risk was found for pulp industry workers, odds ratio (OR)
BACKGROUND. The incidence of non-Hodgkin lymphoma (NHL) has increased in most Western countries during the last few decades. Immunodefective conditions are established risk factors. In 1981, the authors reported an increased risk for NHL following exposure to certain pesticides. The current study was designed to further elucidate the importance of phenoxyacetic acids and other pesticides in the et
Genomic rearrangements in cancer can join the sequences of two separate genes. Studies of such gene fusion events have mainly focused on identification of fusion proteins from the chimeric transcripts. We have previously investigated how fusions instead can affect the expression of intronic microRNA (miRNA) genes that are encoded within fusion gene partners. Here, we extend our analysis to small n
More than 40% of Dutch women are not financially independent. Tax incentives for single earning families encourage this dependence. In this essay in the Dutch financial newspaper Sigrid Hemels argues that it does not make sense to keep such incentives in times as ours in which 40% of all marriages ends in divorce and in which we are faced with increased cost and a reduced workforce due to the agei
We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, we illustrate the criteria used by radiologists for choosing the most appropriate combination of device type for sampling and imag
Sm2+ and Sm3+ co-doped SrB4O7 could be utilized in several high-level optical devices and fundamental knowledge about the optical behavior of these materials benefits the development of luminescent applications. Herein, we report luminescence and its vacuum ultraviolet (VUV) excitation spectra in samarium doped SrB4O7. Both, Sm2+ and Sm3+ luminescence centers have been examined and distinguished i
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Background: Increased inflammation is reported in Major Depressive Disorder (MDD), which may be more pronounced in suicidal subjects. Vitamin D deficiency may drive this pro-inflammatory state due to vitamin D's anti-inflammatory effects. Methods: We quantified plasma 25-hydroxyvitamin D (25(OH)D) and inflammatory markers interleukin (IL)-6 and tumor necrosis factor (TNF)-α, and other inflammatory
My paper studies the nominal system in a dialect of Småland, spoken in Urshult,as it has been coded and transcribed in a volume by Swea Johansson, a native speaker of this dialect. In this variety, a large portion of the weak feminines, in modern Swedish roughly nouns ending -a, for example penna ’pencil’, instead end in -e, penne ’pencil’. Furthermore, the definite form frequently ends in -na, pe: My paper studies the nominal system in a dialect of Småland, spoken in Urshult,as it has been coded and transcribed in a volume by Swea Johansson, a native speaker of this dialect. In this variety, a large portion of the weak feminines, in modern Swedish roughly nouns ending -a, for example penna ’pencil’, instead end in -e, penne ’pencil’. Furthermore, the definite form frequently ends in -na,
We investigated the skin sensitization hazard of glyphosate, the surfactant polyethylated tallow amine (POEA) and two commercial glyphosate-containing formulations using different omics-technologies based on a human dendritic cell (DC)-like cell line. First, the GARD™skin assay, investigating changes in the expression of 200 transcripts upon cell exposure to xenobiotics, was used for skin sensitiz
Cognitive reserve (CR) is thought to protect against the consequence of age- or disease-related structural brain changes across multiple cognitive domains. The neural basis of CR may therefore comprise a functional network that is actively involved in many different cognitive processes. To investigate the existence of such a “task-invariant” CR network, we measured functional connectivity in a cog
The transformation of an atomic nucleus into two excited fission fragments is modeled as a strongly damped evolution of the nuclear shape. As in previous studies, it is assumed that the division of mass and charge is frozen in at a critical neck radius of c0=2.5fm. In order to also determine the energetics, we follow the system further until scission occurs at a smaller neck radius, at which point
Health education materials such as flipbooks enhance learning and deliver key messages in a captivating mode. Validation of such materials is crucial to ensuring implementation fidelity. We conducted a study to achieve two objectives: (a) to develop two flipbooks, one each for adolescents and young married women (YMW); (b) to validate the flipbooks using five parameters, namely, content validity,
There is an established link between birth parameters and risk of adult-onset cancers. The Developmental Origins of Health and Disease concept provides potential underlying mechanisms for such associations, including intrauterine exposure to endogenous hormones (androgens and estrogens), insulin-like growth factors, etc. However, there is conflicting evidence on the association between birth param
Background and purpose: Patients’ adherence to medication is a complex, multidimensional phenomenon. Dispensation data and electronic health records are used to approximate medication-taking through refill adherence. In-depth discussions on the adverse effects of data quality and computational differences are rare. The purpose of this article is to evaluate the impact of common pitfalls when compu
Expanding now familiar debates about the impact of the 'historical turn' upon the field of international law, this article considers some of the different ways in which 'turn to history' scholars have confronted the methodological and theoretical tensions arising from the central, yet paradoxical, role occupied by the sources doctrine in international law. We suggest that the anxiety over the sour
Purpose: We aimed to study the association between country of birth and incident epilepsy in several immigrant groups using Swedish-born individuals as referents. Method: The study population included all adults aged 18 years and older in Sweden, living and deceased, 6,690,598 in the first-generation and 6,683,125 in the second-generation sub-study. Epilepsy was defined as having at least one regi
Background & Aims: There is an unclear association between intake of fish and long-chain n-3 polyunsaturated fatty acids (n-3 LC-PUFAs) and colorectal cancer (CRC). We examined the association between fish consumption, dietary and circulating levels of n-3 LC-PUFAs, and ratio of n-6:n-3 LC-PUFA with CRC using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) coh
Objectives: The aim of this study was to determine the effect of supplemental oxygen in patients with myocardial infarction (MI) on the composite of all-cause death, rehospitalization with MI, or heart failure related to baseline oxygen saturation. A secondary objective was to investigate outcomes in patients developing hypoxemia. Background: In the DETO2X-AMI (Determination of the Role of Oxygen
