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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

Galectins are a group of carbohydrate-binding proteins with a presumed immunomodulatory role and an elusive function on antigen-presenting cells. Here we analyzed the expression of galectin-1 and found upregulation of galectin-1 in the extracellular matrix across multiple tumors. Performing an in-depth and dynamic proteomic and phosphoproteomic analysis of human macrophages stimulated with galecti

What we share: covert commoning in Swedish coliving?

Sharing housing with non-family members has increasingly become a way to reduce costs while pursuing an autonomous yet communal living throughout the life course. During the past decade, a new form of shared housing has entered the Swedish real estate market: coliving. Like shared housing generally, some of the aims of coliving are to help address the housing shortage, decrease loneliness, increas

Exploring patient perspectives : A qualitative inquiry into healthcare perceptions, experiences and satisfaction in Lebanon

BACKGROUND: Patient perspectives have received increasing importance within health systems over the past four decades. Measures of patient experience and satisfaction are commonly used. However, these measures do not capture all the information that is available through engaging with patients. An improved understanding of the various types of patient perspectives and the distinctions between them

Immediate recruitment of dormant coronary collaterals can provide more than half of normal resting perfusion during coronary occlusion in patients with coronary artery disease

Background: Dormant coronary collaterals are highly prevalent and clinically beneficial in cases of coronary occlusion. However, the magnitude of myocardial perfusion provided by immediate coronary collateral recruitment during acute occlusion is unknown. We aimed to quantify collateral myocardial perfusion during balloon occlusion in patients with coronary artery disease (CAD). Methods: Patients

Embracing Monogenic Parkinson's Disease : The MJFF Global Genetic PD Cohort

Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the estimated number of subjects with monogenic PD worldwide are currently represented in the literature and availability of clinical data and clinical trial-ready cohorts is lim

Ett paradigmskifte i synen på sociala problem och en ny era av straff - En tematisk analys av Tidöavtalet och dess innehåll

The publication of the Tidöagreement composed by Sweden's government and the Swedish democrats has encouraged a deep-rooted concern in which ways Swedish society and vulnerable groups will be affected by the said document. Increased knowledge of the Tidöagreement and the way it is composed is vital for understanding the way in which social work will be affected and how vulnerable groups can be

Ungdomars attityder gentemot socialtjänsten - en kvalitativ studie med en kommun i Skåne som utgångspunkt

This study was conducted using a qualitative method, where we interviewed 6 young individuals at a youth center in southern Sweden, with the aim of investigating what attitudes young people hold towards social services as an institution and identifying potential factors that may influence these attitudes, including whether prior experiences with the authority made any difference in their attitudes

Local Government Bodies as Parties to Contracts

This article deals with local government bodies, especially municipalities, as parties to contracts. The primary focus is on the identification and analysis of general problems in Swedish law relating to the competence of a municipality to enter into contracts, and the subsequent legal effects, in the light of the principles and rules of public and private law

The Impact of Classroom Gender Composition on Mental Health of Adolescents: Evidence from the Czech Republic

This essay investigates the impact of classroom gender composition on the mental health of adolescent students. Using data from the Health Behaviours of School-aged Children survey in the Czech Republic, we exploit idiosyncratic classroom variation in the gender composition within the same schools across different grades. We find that a higher proportion of female peers in the classroom has a detr

An Empirical Analysis of the Economic Effects of Sanctions: A Case Study of Iran and Russia

Sanctions, as a foreign policy tool, are increasing in popularity and frequency. This study empirically assesses how different types of sanctions imposed by the European Union, United Nations, and the United States affect the sanctioned states’ GDP growth and degree of openness. Moreover, this study aims to address whether the economic costs of sanctions have undergone any notable changes in the c

Finger-Joints for Laminated Beams : Experimental and Numerical Studies of Mechanical Behaviour

The introduction of laminated timber, glulam being an example, allowed many of the disadvantages associated with solid wood to be overcome. The disadvantages in question are mainly those related to the size and shape limits of structural elements made of solid wood and to the large variability in such material properties of solid wood as strength and stiffness.In the present thesis, which comprise

Influence of the interannual variability of meteorological drought on the cross-interactions of ecological and hydrological drought in the central Spanish Pyrenees

This paper analyzes the influence of the interannual variability of climatic drought on ecological and hydrological droughts for a basin in the central Spanish Pyrenees using variables derived from observations and hydro-ecological simulation in order to determine the possible connection between meteorological, ecological and hydrological drought considering a cascading approach and encompassing d

Assessment of projection interpolation to compensate for the increased radiation dose in DBTMI

The combination of digital breast tomosynthesis (DBT) with other imaging modalities has been investigated in order to improve the detection and diagnosis of breast cancer. Mechanical Imaging (MI) measures the stress over the surface of the compressed breast, using a pressure sensor, during radiographic examination and its response has shown a correlation with the presence of malignant lesions. Thu