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Cytogenetic abnormalities and clonal evolution in an adult hepatoblastoma

Hepatoblastomas usually occur in children < 3 years of age, and only occasional adult cases have been described. To date, 20 cytogenetically abnormal childhood hepatoblastomas have been reported. Karyotypic investigations have shown that most hepatoblastomas are diploid or hyperdiploid, often displaying trisomies for chromosomes 2 and 20. We have cytogenetically investigated an adult hepatoblastom

Comparative study of the microvascular blood flow in the intestinal wall during conventional negative pressure wound therapy and negative pressure wound therapy using paraffin gauze over the intestines in laparostomy.

Higher closure rates of the open abdomen have been reported with negative pressure wound therapy (NPWT) than with other kinds of wound management. We have recently shown that NPWT decreases the blood flow in the intestinal wall, and that the blood flow could be restored by inserting a protective disc over the intestines. The aim of the present study was to investigate whether layers of Jelonet™ (S

Nuclear Data Sheets for A=73

Nuclear structure information available to September 1979 has been reviewed. Results from reaction and decay studies are presented together with adopted level properties.

Ionization and fragmentation of C-60 via multiphoton-multiplasmon excitation

We study the intensity dependence of ionization and fragmentation of buckminsterfullerene (C-60) in strong laser fields. Our data provide strong evidence that at intensities less than or similar to 10(14) W/cm(2) these processes occur predominantly via multiphoton excitation of the 20 eV plasmon resonance of C-60 At least two plasmons have to be created to initiate fragmentation or multiple ioniza

Comparison of automated von Willebrand factor activity assays.

Von Willebrand Disease (VWD) is the most common inherited bleeding disorder. Measurement of von Willebrand factor (VWF) activity in plasma is often based on platelet agglutination stimulated by the ristocetin cofactor activity. Novel assays, based on latex beads with recombinant glycoprotein Ib instead of platelets, have recently been developed but it is unclear whether these can improve the diagn

Simple and Complex Spike Firing Patterns in Purkinje Cells During Classical Conditioning.

Classical blink conditioning is known to depend critically on the cerebellum and the relevant circuitry is gradually being unravelled. Several lines of evidence support the theory that the conditioned stimulus is transmitted by mossy fibers to the cerebellar cortex whereas the unconditioned stimulus is transmitted by climbing fibers. This view has been dramatically confirmed by recent Purkinje cel

Analysis of the PdII spectrum in the ultraviolet and infrared regions

The knowledge of the Pd II spectrum and term system has been extended by means of observations with Fourier transform and high dispersion photographic instruments in the infrared (8100 - 40000 Angstrom) and ultraviolet (1040 - 3100 Angstrom) regions. 320 lines have been classified and measured with high accuracy (+/-0.05-0.003 cm(-1) in the infrared, +/-0.002-0.0005 Angstrom in the ultraviolet). T

The blessings and perils of female rule : new perspectives on the reigning queens of Patani, c. 1584–1718

Only in a handful of cases in world history has female rule been seen by contemporary observers as desirable and been sustained for long periods of time. Drawing on European, Malay and Chinese sources, this article investigates the reasons for the institutionalisation of female rule in the Malay sultanate of Patani (presently in southern Thailand) for most of the period between c. 1584 and 1711. I

Dead and forgotten - postmortem time before discovery as indicator of social isolation and inadequate mental healthcare in schizophrenia.

The psychiatric care of patients with schizophrenia has changed dramatically following the "deinstitutionalization" of mental health care in many Western countries. In a study of forensic autopsies in the Swedish city of Malmö between 1952 and 2005, we found an increase over time in the number of patients with schizophrenia whose bodies were not discovered until late after death, which correlated

Microarray Experiments to Uncover Toll-Like Receptor Function.

This chapter is intended as a handbook for anyone interested in using microarrays to study Toll-like receptor (TLR) function or any other biological question. Although microarray technology has developed into a standard tool at many laboratories disposal, most of the actual microarray processing is done by core facilities using highly specialized equipment. This chapter only briefly describes thes