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Phytate, zinc, iron and calcium content of common Bolivian food, and implications for mineral bioavailability

The content of zinc, iron, calcium and phytate in the 16 most consumed foods from 5 villages in a tropical rural area of Bolivia was analyzed. The fooditems were selected according to a completed food frequency questionnaire. Minerals were analyzed by atomic absorption and phytates by HPIC chromatography. The molar ratios of phytate:mineral are presented as indication of the mineral bioavailabilit

The Progressive Loss of Syntactical Structure in Bird Song along an Island Colonization Chain

Cultural transmission can increase the flexibility of behavior, such as bird song. Nevertheless, this flexibility often appears to be constrained, sometimes by preferences for learning certain traits over others, a phenomenon known as "biased" learning or transmission [1]. The sequential colonization of the Atlantic Islands by the chaffinch (Fringilla coelebs) [2] provides a unique model system in

Horseshoe-like patterns in first-order 3D Gauss-Lagrange waves with directional spreading

The Gauss–Lagrange model for ocean waves describes the vertical and horizontal movements of water particles as three correlated Gaussian fields. The model can produce irregular waves, asymmetric in both vertical and horizontal direction, and by judicious choice of a single skewness parameter the front–back asymmetry can be regulated to realistic values. In this paper, it is shown that this additiv

Working with Facebook in Public Libraries: A Backstage Glimpse into the Library 2.0 Rhetoric

Ideals and visions of a Library 2.0 have in recent years been widely discussed in public library research and practice. Influenced by the Web 2.0 discourse, the Library 2.0 rhetoric has to a large extent been coloured by utopian and revolutionary overtones, identifying social media as key to transforming the public library institution. While previous research has primarily addressed this developme

TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells.

The transient receptor potential, vanilloid 4 (TRPV4), is a calcium permeable ion channel expressed in airway epithelial cells. Based on studies of cell lines and animals, TRPV4 has been suggested to play a role in the regulation of ciliary beat frequency (CBF). Whether the same is true for human ciliated epithelial cells is not known. Therefore, the aim was to examine the expression and function

Epigenetic Economic Dynamics: The evolution of big internet business ecosystems, evidence for patents

The aim of this article is to contribute to literature with new findings from biogenetics that are becoming increasingly important. In particular, we will discuss the new analytic frameworks that may open as a result of the incorporation of epigenetics in evolutionary economic thinking. This new approach is illustrated by studying the evolution of big Internet industry groups such as Apple, Google

When Is the Deep Inferior Epigastric Artery Flap Indicated for Breast Reconstruction in Patients not Treated With Radiotherapy?

BACKGROUND: It is controversial whether breast reconstruction with a microvascular free flap should be done without restrictions in patients who have not had radiotherapy. Many regard it as too expensive, but some consider it better and more economically advantageous than an implant reconstruction. METHODS: Databases of publications were searched to find out under what conditions is it suitable to

Effectiveness and survival-on-drug of certolizumab pegol in rheumatoid arthritis in clinical practice: results from the national Swedish register

Objectives: Evidence regarding the efficacy and effectiveness of certolizumab pegol (CZP) in rheumatoid arthritis (RA) patients who have failed to respond to treatment with a tumour necrosis factor inhibitor (TNFi) is limited. The aim of this study was to describe the effectiveness and survival-on-drug of CZP in a real-life setting, both in TNFi-naive patients and in patients who had previously fa

Adaptation in the optical properties of the crystalline lens in the eyes of the Lessepsian migrant Siganus rivulatus

Vision is an important source of information for many animals. The crystalline lens plays a central role in the visual pathway and hence the ecology of fishes. In this study, we tested whether the different light regimes in the Mediterranean and Red Seas have an effect on the optical properties of the lenses in the rivulated rabbitfish, Siganus rivulatus. This species has migrated through the Suez

Molecular Epidemiology of Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Isolates from Norway and Sweden Shows Import of International Clones and Local Clonal Expansion

Scandinavia is considered a region with a low prevalence of antimicrobial resistance. However, the number dof multidrug-resistant (MDR) Gram-negative bacteria is increasing, including metallo-beta-lactamase (MBL)-producing Pseudomonas aeruginosa. In this study MBL-producing P. aeruginosa isolates identified in Norway (n = 4) and Sweden (n = 9) from 1999 to 2007 were characterized. Two internationa

Future vegetation changes in thawing subarctic mires and implications for greenhouse gas exchange-a regional assessment

One of the major concerns regarding climate change in high latitudes is the potential feedback from greenhouse gases (GHG) being released from thawing peat soils. In this paper we show how vegetational patterns and associated GHG fluxes in subarctic palsa (peat mounds with a permanently frozen core) mires can be linked to climate, based on field observations from fifteen palsa sites distributed in

Structural Parameters determined by microCT in normal and osteoporotic human trabecular Bone are Affected Differently by image resolution

Abstract in Undetermined This study employed microCT to investigate whether image resolution affects bone structural parameters differently in healthy normal and osteoporotic trabecular bone. With increasing image voxel size, the originally detected differences between sample groups diminished. The results suggest that structural differences may not be reliably detected with clinical scanners.

Synthesis of P1 '-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol

Seven novel tertiary alcohol containing linear HIV-1 protease inhibitors (PIs), decorated at the para position of the benzyl group in the P1' side with (hetero)aromatic moieties, were synthesized and biologically evaluated. To study the inhibition and antiviral activity effect of P1-P3 macro-cyclization, 14- and 15-membered macrocyclic Pis were prepared by ring-closing metathesis of the correspond

ASSOCIATION OF BTG2, CYR61, ZFP36, AND SCD GENE POLYMORPHISMS WITH GRAVES' DISEASE AND OPHTHALMOPATHY.

Background: Environmental and genetic factors predispose an individual to the development of Graves' disease (GD). In an expression study of intraorbital tissue, adipocyte-related immediate early genes (IEGs) and immunomodulatory genes were found to be overexpressed in patients with Graves' ophthalmopathy (GO). We hypothesized that genetic variations in these genes could be associated with GD and/

Effects of blood ΔR(2)* non-linearity on absolute perfusion quantification using DSC-MRI: Comparison with Xe-133 SPECT.

PURPOSE: To evaluate whether a non-linear blood ΔR(2)*-versus-concentration relationship improves quantitative cerebral blood flow (CBF) estimates obtained by dynamic susceptibility contrast (DSC) MRI in a comparison with Xe-133 SPECT CBF in healthy volunteers. MATERIAL AND METHODS: Linear as well as non-linear relationships between ΔR(2)* and contrast agent concentration in blood were applied to

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade.

Mitotic index is an important component of histologic grade and has an etiologic role in breast tumorigenesis. Several small candidate gene studies have reported associations between variation in mitotic genes and breast cancer risk. We measured associations between 2,156 single nucleotide polymorphisms (SNPs) from 194 mitotic genes and breast cancer risk, overall and by histologic grade, in the B

Proficiency of drug susceptibility testing of Mycobacterium tuberculosis against pyrazinamide: the Swedish experience

BACKGROUND: Pyrazinamide (PZA) is a key drug in the treatment of tuberculosis (TB), including multidrug-resistant TB. Drug susceptibility testing (DST) of Mycobacterium tuberculosis against PZA is not included in the World Health Organization's yearly proficiency testing. There is an increasing need to establish quality control of PZA DST. OBJECTIVE: To evaluate the performance of PZA DST and to i