ZNF224 is a member of the Kruppel-associated box zinc finger proteins (KRAB-ZFPs) family. It was originally identified as a transcriptional repressor involved in gene-specific silencing through the recruitment of the corepressor KAP1, chromatin-modifying activities, and the arginine methyltransferase PRMT5 on the promoter of its target genes.Recent findings indicate that ZNF224 can behave both as

In our homes we enjoy daylight reaching the rooms through the windows, and artificial lighting when there is not enough daylight available. Electrical lighting has been used in Western homes since the late 1910s. We have experienced the technical development from warm incandescent light bulbs to energy-efficient light emitting diods (LED). In Sweden we lack daylight in winter and have a lot of day

OBJECTIVE: To assess mortality related to musculoskeletal (MSK) disorders and rheumatoid arthritis (RA), specifically, among adults (aged ≥ 20 yrs) in southern Sweden using the multiple-cause-of-death approach.METHODS: All death certificates (DC; n = 201,488) from 1998 to 2014 for adults in the region of Skåne were analyzed when mortality from MSK disorders and RA was listed as the underlying and

We assessed the relationship between phosphocreatine (PCr) and creatine (Cr) content and creatine kinase (CK) activity in skeletal muscle of mice. The PCr and total Cr (tCr) concentrations, as well as CK activity, in hindlimb muscles of mice, with or without the cytosolic and mitochondrial isoforms of muscle creatine kinase (wild-type or CK--/-- mice), were determined by in vivo magnetic resonance

New elements discovered during past decades have been created in fusion reactions where a lighter nucleus is collided with a heavier one. The new elements created often decay by emitting α particles. From the half-lives of the decays and the energies of the emitted particles one may extract some properties of the new elements. In this talk the recent work performed by the Lund group to model α dec

Based on a study of two mediation centers in Sweden, this research shows how mediators encourage victim and offender impression management, regarding looks, attitudes, and speech. It shows how they supervise the emotion work of participants, preparing them for mediation encounters. The author investigates how mediators try to create a “balanced” interaction (e.g., preventing expressed prejudices o

The majority of terrestrial plants associate with arbuscular mycorrhizal (AM) fungi, which typically facilitate the uptake of limiting mineral nutrients by plants in exchange for plant carbon. However, hundreds of non-photosynthetic plant species—mycoheterotrophs—depend entirely on AM fungi for carbon as well as mineral nutrition. Mycoheterotrophs can provide insight into the operation and regulat

Integration of non-dispatchable renewable energy sources such as wind and solar into the grid is challenging due to the stochastic nature of energy sources. Hence, electrical hubs (EH) and virtual power plants that combine non-dispatchable energy sources, energy storage and dispatchable energy sources such as internal combustion generators and micro gas turbines are getting popular. However, desig

The article deals with Jan Karski and Raoul Wallenberg and the different ways that they have been remembered in Poland and Sweden.

The aim of this study is to evaluate the existence of a possible relationship between global deuterium-labeled water (HDO) uptake rates and the diffusion geometry of human glioma xenografts in nude mice. HDO diffusion times in the whole extravascular tumor volume were estimated by combining quantitative (1)H-MR diffusion imaging and morphometric analysis of intercapillary distances in two tumor li

The oxy-fuel combined cycle (OCC) is one of several carbon capture and sequestration (CCS) technologies being developed to reduce CO2 emissions from thermal power plants. The OCC consists of a semi-closed topping Bryton cycle, and a traditional bottoming Rankine cycle. The topping cycle operates with a working medium mixture of mainly CO2 and H2O. This CO2-rich working fluid has significantly diff

Recension av Catherine Merridale, "Lenins resa"

This paper illustrates some biochemical and pharmacological properties of two natural marine products such as trabectedin (ET-743, Yondelis) and aplidine. Trabectedin has shown clinical antitumor activity in refractory soft tissue sarcoma and ovarian cancer. The lack of cross resistance of trabectedin with other chemotherapeutic drugs is presumably related to its peculiar mode of action, that seem

Background: Effects of increased adenosine dose in the assessment of fractional flow reserve (FFR) were studied in relation to FFR results, hemodynamic effects and patient discomfort. FFR require maximal hyperemia mediated by adenosine. Standard dose is 140 μg/kg/min administrated intravenously. Higher doses are commonly used in clinical practice, but an extensive comparison between standard intra

This thesis is a study of the phenomenon modern furniture classics in a contemporary Swedish context. Classics have a strong and normative position in the world of design, and what the concept of modern furniture classic entails is often taken for granted and rarely problematised. The main objectives of the study is to investigate what a modern furniture classic is and how it attains the status of

Background: Previous in vitro studies have shown that mucin 4 (MUC4) confers resistance toward gemcitabine in pancreatic cancer cells. To date, there are few clinical studies corroborating these findings. The aim of this study was to evaluate the predictive impact of MUC4 expression on survival in patients with resectable pancreatic cancer receiving adjuvant gemcitabine. Materials and methods: MUC