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Sweden : Past Didactic Influence and Present Efforts to Create Learning Progressions

The Swedish school system comprises three school types: preschool, compulsory school (9 years) and secondary school (3 years). The latest curriculum reform was completed in 2011, updating policy documents and restructuring syllabuses, clarifying subject specific abilities and knowledge requirements. In 2012, national tests in geography were instituted for years 6 and 9, yielding support for equal

Noise colour and the risk of population extinctions

A recurrent problem in ecology and conservation biology is to estimate the risk of population extinctions. Extinction probabilities are not only imperative for conservation and management, but may also elucidate basic mechanisms of the regulation of natural populations. The usual way of modelling stochastic influence on population dynamics has been to assume that the external noise is uncorrelated

Robust time-of-arrival self calibration and indoor localization using Wi-Fi round-trip time measurements

The problem of estimating receiver-sender node positions from measured receiver-sender distances is a key issue in different applications such as microphone array calibration, radio antenna array calibration, mapping and positioning using UWB and mapping and positioning using round-trip-time measurements between mobile phones and Wi-Fi-units. Thanks to recent research in this area we have an incre

Optimization of Routing and Reconfiguration Overhead in Programmable Processor Array Architectures

In this paper, we present a constraint programming-based approach for optimization of routing and reconfiguration overhead for a class of reconfigurable processor array architectures called weakly programmable. For a given set of different algorithms the execution of which is supposed to be switched upon request at run-time, we provide static solutions for optimal routing of data between processor

Exogenous BDNF and Chondroitinase ABC Consisted Biomimetic Microenvironment Regulates Survival, Migration and Differentiation of Human Neural Progenitor Cells Transplanted into a Rat Auditory Nerve

Current putative regeneration oriented studies express possible role of stem cell based implantation strategy in the restoration of fundamental perception of hearing. The present work utilizes a rat auditory nerve (AN) directed transplantation of human neural progenitor cells (HNPCs) as a cell replacement therapy for impaired auditory function. Groups of b-bungarotoxin induced auditory function co

Theoretical estimates of supernova-neutrino cross sections for the stable even-even lead isotopes : Charged-current reactions

A detailed study of the charged-current supernova electron neutrino and electron antineutrino scattering off the stable even-mass lead isotopes A=204, 206, and 208 is reported in this work. The proton-neutron quasiparticle random-phase approximation (pnQRPA) is adopted to construct the nuclear final and initial states. Three different Skyrme interactions are tested for their isospin and spin-isosp

Observation of a topologically non-trivial surface state in half-Heusler PtLuSb(001) thin films

The discovery of topological insulators, materials with bulk band gaps and protected cross-gap surface states in compounds such as Bi2Se3, has generated much interest in identifying topological surface states (TSSs) in other classes of materials. In particular, recent theoretical calculations suggest that TSSs may be found in half-Heusler ternary compounds. If experimentally realizable, this would

Single-Cell Sequencing of Human Pancreatic Islets—New Kids on the Block

RNA sequencing of human pancreatic islets has provided important insights into the islet transcriptome but little information on the specific cells. In this issue, Segerstolpe et al. (2016) and Xin et al. (2016b) report on the transcriptome of single pancreatic cells from non-diabetic and type 2 diabetic donors.

Socio-economic inequalities in health and health service use among older adults in India : results from the WHO Study on Global AGEing and adult health survey

Objective The objectives of this study were to measure socio-economic inequalities in self-reported health (SRH) and healthcare visits and to identify factors contributing to health inequalities among older people aged 50-plus years. Study design This study is based on a population-based, cross-sectional survey. Methods We accessed data of 7150 older adults from the World Health Organization's Stu

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute liver injury (APAP-ALI) and justifies development of anti-inflammatory therapies with therapeutic efficacy beyond the therapeutic window of the only current treatment option, N-acetylcysteine (NAC). The inflammatory mediator, h

The use of the partnering concept for Public-Private collaboration : How well does it really work?

This paper critically scrutinizes the key success factors and tools described in the partnering literature by exploring how they are implemented in a public–private partnering collaboration. In addition to this the paper investigates to what extent these tools facilitate the relationship between the parties in a partnering process. The empirical data consist of two longitudinal case studies. Both

Experimental biodiversity enrichment in oil-palm-dominated landscapes in Indonesia

Tropical biodiversity is threatened by the expansion of oil-palm plantations. Reduced-impact farming systems such as agroforests, have been proposed to increase biodiversity and ecosystem functioning. In regions where oil-palm plantations already dominate the landscape, this increase can only be achieved through systematic ecological restoration. However, our knowledge about the underlying ecologi

N-glycosylation proteome enrichment analysis in kidney reveals differences between diabetic mouse models

Background: Diabetic nephropathy (DN) is a late complication in both type 1 diabetes mellitus (T1DM) and T2DM. Already at an early stage of DN morphological changes occur at the cell surface and in the extracellular matrix where the majority of the proteins carry N-linked glycosylations. These glycosylated proteins are highly important in cell adhesion and cell-matrix processes but not much is kno