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Boende och äldre

En beskrivning av de olika boendeformer som finns för äldre personer och som utgår från deras existerande eller befarade framtida funktionsnedsättningar samt av de rättsliga problem som då kan uppkomma.

Electro-viscoelastic response of an acrylic elastomer analysed by digital image correlation

Experimental investigations are presented with respect to the electromechanically coupled and time-dependent behaviour of an acrylic elastomer, VHB 4910. For the electromechanically coupled experiments different biaxial pre-stretches have been considered and full-field measurements were made using three-dimensional surface digital image correlation. Both equi- biaxial and non equi-biaxial pre-stre

Remissyttrande: Samlad kunskap - stärkt handläggning (SOU 2017:25)

En beskrivning av tre viktiga principiella synpunkter på lagförslaget.1 Det beslutsstöd som föreslås bör vara normerande.2 det behövs en informationskampanj riktad till allmänheten om skillnaden mellan att vara sjuk eller frisk enligt arbetsskadeförsäkringens synsätt och enligt sjukförsäkringens synsätt.3 Om arbetsskadesjukpenning införs bör den bygga på bygga på arbetskadelivräntans sätt att betr

The prognostic role of cancer stem cell markers for long-term outcome after resection of colonic liver metastases

Background/Aim: To assess the expression of cancer stem cell (CSC) markers CD44, CD133 and CD24 in colon cancer liver metastases and analyse their predictive value for overall survival (OS) and disease-free survival (DFS) after liver resection. Materials and Methods: Patients operated on for colon cancer liver metastases were included. CSC marker expression was determined through immunohistochemis

Precision medicine in obesity and type 2 diabetes : The relevance of early-life exposures

BACKGROUND: Type 2 diabetes is highly prevalent and devastating. Obesity is a diabetogenic factor, driving insulin resistance and a compensatory demand for increased insulin secretion from the pancreatic cells; a failure to address this demand results in diabetes. Accordingly, primary and secondary prevention of obesity are at the core of diabetes prevention programs. The development of obesity an

Nuclear medicine : Physics and instrumentation special feature review article: SPECT/CT: An update on technological developments and clinical applications

Functional nuclear medicine imaging with single-photon emission CT (SPECT) in combination with anatomical CT has been commercially available since the beginning of this century. The combination of the two modalities has improved both the sensitivity and specificity of many clinical applications and CT in conjunction with SPECT that allows for spatial overlay of the SPECT data on good anatomy image

Prenatal exposure to acetaminophen and children's language development at 30 months

Objective: To examine prenatal APAP exposure in relation to language development in offspring at 30 months of age. Method: A population-based pregnancy cohort study including 754 women who enrolled in the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) study in pregnancy week 8-13. Two exposure measures were used: (1) maternally reported number of APAP tablets take

Effects of internet-based cognitive behavioural therapy and physical exercise on sick leave and employment in primary care patients with depression : two subgroup analyses

OBJECTIVES: Depression can negatively impact work capacity, but treatment effects on sick leave and employment are unclear. This study evaluates if internet-based cognitive behavioural therapy (ICBT) or physical exercise (PE), with already reported positive effects on clinical outcome and short-term work ability, has better effects on employment, sick leave and long-term work ability compared with

Cerebral palsy in extremely preterm infants

Background and Objectives: The risk of cerebral palsy (CP) is high in preterm infants and is often accompanied by additional neurodevelopmental comorbidities. The present study describes lifetime prevalence of CP in a population-based prospective cohort of children born extremely preterm, including the type and severity of CP and other comorbidities (ie, developmental delay and/or cognitive impair

The number of oocytes retrieved during IVF : A balance between efficacy and safety

STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

The transcription factor ZNF224 plays a key proapoptotic role in chronic myelogenous leukemia (CML), by modulating Wilms Tumor protein 1 (WT1) dependent apoptotic genes transcription. Recently, we demonstrated that Bcr-Abl signaling represses ZNF224 expression in Bcr-Abl positive CML cell lines and in CML patients. Interestingly, Imatinib and second-generation tyrosine kinase inhibitors specifical

Quality transformation of dissolved organic carbon during water transit through lakes : contrasting controls by photochemical and biological processes

Dissolved organic carbon (DOC) may be removed, transformed, or added during water transit through lakes, resulting in changes in DOC composition and pigmentation (color). However, the process-based understanding of these changes is incomplete, especially for headwater lakes. We hypothesized that because heterotrophic bacteria preferentially consume noncolored DOC, while photochemical processing re

The Concordant Space of Biomedical Science : How Individuals with Parkinson's Disease Synchronize themselves with Clinical Trials

Parkinson’s disease (PD) becomes more frequent as populations grow older in western countries. Levodopa exists as medication, but is connected with side-effects. In search for an alternative therapy, patients become agents in different ways. The role as participant in clinical trials, not least, is one of these possibilities for lay influence in scientific matters. In this presentation we ask how

Temporal trends and regional disparity in rheumatoid arthritis and gout hospitalizations in Sweden, 1998-2015

Hospitalization is an important component of rheumatoid arthritis (RA) and gout economic burden. This study aimed to assess temporal trends and regional disparities in RA and gout hospitalizations among people aged ≥ 20 years in Sweden during 1998-2015. Data on hospital admissions with a principal diagnosis of RA or gout were collected from the National Patient Register. Age-standardized hospitali