Single nucleotide polymorphisms (SNPs) of cytochrome P450 (CYPs) and UDP-glucuronosyltransferase (UGTs) genes have been proposed to influence phthalates and 1,2-cyclo-hexanedicarboxylic acid diisononyl ester (DINCH) biotransformation but have not been investigated on a populational level. We investigated the role of SNPs in CYP2C9, CYP2C19, CYP2D6, UGT2B15, and UGT1A7 genes in the biotransformatio

Per- and polyfluoroalkyl substances (PFAS) are of high concern for the environment, wildlife, and human health due to their persistence and potential to cause adverse health effects. Despite political measures to restrict the production and distribution of PFAS and to limit the exposure of populations, PFAS can be measured at commonly high detection frequencies in human samples. Thus, this pilot s

Phthalates and 1,2-Cyclohexane dicarboxylic acid diisononyl ester (DINCH), bisphenols (BPs), parabens (PBs), and triclosan (TCS) are high-production-volume chemicals of pseudo-persistence that are concerning for the environment and human health. This study aims to assess the exposure to 10 phthalates, DINCH, and environmental phenols (3 BPs, 7 PBs, and TCS) of Slovenian men (n = 548) and lactating

Lead (Pb) is a global contaminant associated with multiple adverse health effects. Humans are especially vulnerable during critical developmental stages. During pregnancy, exposure to Pb can occur through diet and release from maternal bones. Apolipoprotein E gene (APOE) variants (ɛ2, ɛ3, ɛ4 alleles) may influence sex steroid hormones, bone metabolism, and Pb kinetics. We examined the interplay am

The genetic susceptibility to low-level lead (Pb) exposure in general populations has been poorly investigated and is limited to the single nucleotide polymorphism (SNP) rs1800435 in the delta-aminolevulinic acid dehydratase gene (ALAD). This study explored associations between ten selected ALAD SNPs with Pb concentrations in blood (BPb) and urine (UPb) among 281 men aged 18-49 years from Slovenia

Chemicals such as bisphenols, parabens and triclosan are endocrine disrupting chemicals. They are used in a wide variety of consumer products, making human exposure to those chemicals widespread. In the present study, levels of three bisphenols (bisphenol A, F and S), 7 parabens (methyl-, ethyl-, isopropyl-, propyl-, isobutyl-, butyl-, benzyl paraben) and triclosan were measured in first morning v

Persistent organic pollutants (POPs) represent a concern for the environment and human health due to their persistence and toxicity. Exposure in Slovenia is geographically differentiated because the country, as part of former Yugoslavia, has a history of industry and regional contamination and is – at the same time – known for its clean nature. The PCB pollution of the Krupa River drew the public'

Phthalates are widespread contaminants with differing chemical characteristics, which largely determine their product applications, and they can leach into the environment. Due to their endocrine disruptive properties at long-term low-level exposure, they propose a health threat to people that has been associated with several adverse health effects such as: decreased male fertility and impacts on

Patterns of lead and other trace metals were examined in 122 Eurasian eagle owls Bubo bubo found dead in Sweden in the period 1978–2013. Environmental lead (Pb) has decreased over recent decades from reduced anthropogenic emissions but mortality by Pb poisoning is still frequently reported for avian raptors and scavengers exposed to Pb ammunition. One objective here was to determine if Pb concentr

Human biomonitoring (HBM) frameworks assess human exposure to hazardous chemicals. In this review, we discuss and summarize sample preparation procedures and analytical methodology for six groups of chemicals of emerging concern (CECs), namely diisocyanates, benzotriazoles, benzothiazoles, 4-methylbenzylidene camphor, isothiazolinones, fragrances, and non-phthalate plasticizers, which are increasi

The European Human Biomonitoring Initiative (HBM4EU) assessed human biomonitoring data on phthalates in children and adolescents, that were sampled between 2014 and 2021, in a harmonised way. These so-called “HBM4EU Aligned Studies” revealed that almost all children and adolescents were exposed to multiple phthalates concurrently. Some phthalates have been shown to act in a dose-additive manner, t

Human biomonitoring (HBM) is a rapidly developing field that is emphasized as an important approach for the assessment of health risks. However, its value for health risk assessment (HRA) remains to be clarified. We performed a review of publications concerned with applications of HBM in the assessment of health risks. The selection of publications for this review was limited by the search engines

Within the European Human Biomonitoring (HBM) Initiative HBM4EU we derived HBM indicators that were designed to help answering key policy questions and support chemical policies. The result indicators convey information on chemicals exposure of different age groups, sexes, geographical regions and time points by comparing median exposure values. If differences are observed for one group or the oth

Recension av Karin Westin Tikkanens bok Latin: handbok i odödlighet

Den här studien undersöker social interaktion i den virtuella verkligheten genom en fallstudie av ett sexuellt ofredande i den interaktiva teaterpjäsen AI-partiet. Genom en kvalitativ metod bestående av semi-strukturerade intervjuer och en tematisk analys av händelsen, utforskar studien hur interaktion i en virtuell verklighet skapar mening, samt vad som händer med vår interaktion i en miljö där g

“Den gröna revolutionen; Hur Wicked blir en spegling av samtiden", ett filmpoetiskt perspektiv utifrån makt och utanförskap. Skriven av Nova Bergman, Moa Fors och Moa Nittmar, enheten för Medie- och kommunikationsvetenskap, vid institutionen för kommunikation och medier vid Lunds universitet. Reboot-trenden har blivit allt vanligare i dagens samtid. Därför undersöker denna uppsats hur större

In this paper, we introduce OT-PCA, a novel approach for conducting Plaintext-Checking (PC) oracle based side-channel attacks, specifically designed for Hamming Quasi-Cyclic (HQC). By calling the publicly accessible HQC decoder, we build offline templates that enable efficient extraction of soft information for hundreds of secret positions with just a single PC oracle call. Our method addresses cr

Statistik visar att diskriminering på arbetsplatser och på arbetsmarknaden är ett vanligt förekommande fenomen. HR-yrket präglas av låg representation av personer födda utanför Norden och är dessutom starkt kvinnodominerat. Syftet med denna uppsats är att undersöka hur HR-professionella med etnisk minoritetsstatus, i kombination med andra identitetsaspekter, upplever och hanterar utmaningar i sitt

The concept of a socially sustainable society is linked to the notion of equal access to high-quality welfare services and an equitable distribution of common resources. The rationale behind the introduction of private actors to provide welfare services is that greater choice will result in higher quality of service for individuals, achieved through a co-creation process. The purpose of this study