The hippocampus is a primary region affected in Alzheimer's disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mechanisms. To address this issue, we examined the cellular origin and progression of AD pathogenesis by comparing patient-based model systems including iPSC-derived brain cells transplanted into

IntroductionLow serum selenium and altered tumour RNA expression of certain selenoproteins are associated with a poor breast cancer prognosis. Selenoprotein expression stringently depends on selenium availability, hence circulating selenium may interact with tumour selenoprotein expression. However, there is no matched analysis to date.MethodsThis study included 1453 patients with newly diagnosed

CC-GLPDC codes are a class of generalized low-density parity-check (GLDPC) codes where the constraint nodes (CNs) represent convolutional codes. This allows for efficient decoding in the trellis with the forward-backward algorithm, and the strength of the component codes easily can be controlled by the encoder memory without changing the graph structure. In this letter, we extend the class of CC-G

Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces

Syftet med mitt arbete är att utveckla min egen interpretation av andra satsen i Haydns cellokonsert i C-dur. Genom att systematiskt lyssna på hur ett antal berömda cellister tolkat musiken, genom att jämföra parametrarna tempo, vibrato, dynamik och frasering har jag kunnat upptäcka vissa samband och avvikelser mellan tolkningarna. Med hjälp av denna nya kunskap har det varit möjligt för mig att mThe purpose of this study was to develop my own interpretation of the second movement of Haydn’s cello concerto in C major. By systematically listening to how famous cellists have interpreted this piece, and by comparing the parameters tempo, vibrato, dynamics and phrasing, I have been able to discover certain connections and differences between the interpretations. With help of this knowledge it

Hourless and at large. Exhibition curated by Barbara Piwowarska. Casa São Roque. Porto, Portugal. February 19 – September 30, 2023. Opening February 18, 2023.

The opening seconds of Emily Wardill’s film Identical (2023) are simple and elemental: the seductive play of light on water. Or, put another way, the film begins by depicting the moment where one thing bends, reflects and distorts another – and is seen differently as a consequence. This jewel-like mirage is doubled across a second screen. Initially, each image appears indistinguishable from the ot

Solo show at KW , Berlin, Germany. Text by Mason Leaver-Yap:The opening seconds of Emily Wardill’s film Identical (2023) are simple and elemental: the seductive play of light on water. Or, put another way, the film begins by depicting the moment where one thing bends, reflects and distorts another – and is seen differently as a consequence. This jewel-like mirage is doubled across a second screen.

Background: Differential diagnosis of rhabdomyosarcoma (RMS) is challenging. Sineoculis homeobox homolog 1 (SIX1) is an oncogene involved in skeletal muscle differentiation. We compared protein expression patterns of SIX1 in RMS and its most common differential diagnoses. Methods: SIX1 immunohistochemistry in 36 RMS and in 33 tumors from seven differential diagnostic subtypes were evaluated. The f

Introduction: Heterogeneity in composition and spatial configuration of landscape elements support diversity and abundance of flower-visiting insects, but this is likely dependent on taxonomic group, spatial scale, weather and climatic conditions, and is particularly impacted by agricultural intensification. Here, we analyzed the impacts of both aspects of landscape heterogeneity and the role of c

Ebola virus disease (EVD) is a rare but highly contagious and lethal disease that occurs predominantly in African countries, with a case-fatality rate of 30–90%. The causative viral pathogens of EVD are within the genus Ebolavirus in the family Filoviridae. The primary route of human-to-human transmission is through direct contact with blood, bodily fluids and secretions from infected individuals.

Denna avhandling undersöker hur mer jämlika och inkluderande livsmiljöer kan uppnås genom att använda Universal Utformning (UU) för att införliva mänsklig mångfald i alla stadier av planering och byggande. Det pågående utanförskapet av personer med funktionsnedsättning från den byggda miljön beror inte på bristande kunskap om hur man kan åtgärda befintliga hinder eller om hur man undviker att skapThis thesis explores how more equal and inclusive living environments can be achieved by using Universal Design (UD) to incorporate human diversity in all stages of planning and construction. The ongoing exclusion of persons with disabilities from the built environment does not result from a lack of knowledge on how to remedy existing obstacles nor of how to avoid creating new ones. Other reasons

Motivational Practice provides a rich account of how teachers who are successful in motivating their students negotiate classroom relationships, and create engaging learning opportunities. It sheds light on how motivation emerges through teacher–student relationships, and in classroom activities.Drawing on examples of motivational practice from the Motivational Teaching in Swedish Secondary Englis

Lung neuroendocrine neoplasms (NEN) are a heterogeneous population of neoplasms with different pathology, clinical behavior, and prognosis compared to the more common lung cancers. The diagnostic work-up and treatment of patients with lung- NEN has undergone major recent advances and new methods are currently being introduced into the clinic. These Nordic guidelines summarize and update the Nordic

In this paper, balancing electricity production using renewable energy such as wind power, PV cells, hydropower, and CHP (combined heat and power) with biomass is carried out in relation to electricity consumption in primarily one major region in Sweden, SE-3, which contains 75% of the country’s population. The time perspective is hours and days. Statistics with respect to power production and con

In this article, we introduce a new community-contributed command, xtnumfac, for estimating the number of common factors in time-series and panel datasets using the methods of Bai and Ng (2002, Econometrica 70: 191–221), Ahn and Horenstein (2013, Econometrica 81: 1203–1227), Onatski (2010, Review of Economics and Statistics 92: 1004–1016), and Gagliardini, Ossola, and Scaillet (2019, Journal of Ec