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Text message-based lifestyle intervention in primary care patients with hypertension: a randomized controlled pilot trial

Published 6 December 2020 Thirty participants were randomized to the intervention group with four lifestyle-promoting text messages sent every week for six months. The control group received usual care. The baseline and follow-up visits for all 60 patients included measurements of blood pressure, anthropometrics, blood tests and a self-reported questionnaire. Read more at Full article: Text messag

https://www.lupop.lu.se/article/text-message-based-lifestyle-intervention-primary-care-patients-hypertension-randomized-controlled - 2025-03-15

Desloratadine and loratadine stand out among common H1-antihistamines for association with improved breast cancer survival

Published 6 December 2020 We investigated use of the six major H1-antihistamines (cetirizine, clemastine, desloratadine, ebastine, fexofenadine and loratadine) and breast cancer-specific and overall mortality in a nation-wide register-based study of all 61,627 Swedish women diagnosed with breast cancer 2006–2013. Both peri- and post-diagnostic antihistamine use was analyzed using Cox regression mo

https://www.lupop.lu.se/article/desloratadine-and-loratadine-stand-out-among-common-h1-antihistamines-association-improved-breast - 2025-03-15

Longitudinal study of cognitive function in glioma patients treated with modern radiotherapy techniques and standard chemotherapy

Published 7 December 2020 Cognitive function is an important outcome measure in patients with brain tumor, providing information about the patient’s clinical situation, treatment effects and possible progressive disease. The aim of this longitudinal study was to evaluate effects of the currently used radiation and chemotherapy treatment on cognitive function and to investigate associations between

https://www.lupop.lu.se/article/longitudinal-study-cognitive-function-glioma-patients-treated-modern-radiotherapy-techniques-and - 2025-03-15

Unacceptable pain in the BARFOT inception cohort of patients with rheumatoid arthritis: a long-term study

Published 7 December 2020 Unacceptable pain was frequent. At the 15 year follow-up visit, 34% had unacceptable pain. Patients with unacceptable pain had, compared with patients with tolerable pain, significantly more disease activity, worse patient global assessment, and worse function on the Health Assessment Questionnaire and Signals of Functional Impairment, but the degree of joint destruction

https://www.lupop.lu.se/article/unacceptable-pain-barfot-inception-cohort-patients-rheumatoid-arthritis-long-term-study - 2025-03-15

Identifying and validating housing adaptation client profiles – a mixed methods study

Published 8 December 2020 An increasing number of people will live with disabilities in their homes and consequently, the need for home-based interventions will increase. Housing adaptations (HAs) are modifications to the physical home environment with the purpose to enhance independence for a heterogeneous group of people. Increasing the knowledge of the characteristics of HA clients by exploring

https://www.lupop.lu.se/article/identifying-and-validating-housing-adaptation-client-profiles-mixed-methods-study - 2025-03-15

The young protester: the impact of belongingness needs on political engagement

Published 8 December 2020 As institutional forms of political engagement continue to decline, participation in protests steadily become more common. These trends are particularly strong among younger citizens. Previous research indicates that social factors can explain participation in political protests, and that younger citizens’ participation in protests is more affected by social ties than old

https://www.lupop.lu.se/article/young-protester-impact-belongingness-needs-political-engagement - 2025-03-15

Time trends in pediatric fractures in a Swedish city from 1950 to 2016

Published 9 December 2020 Malmö city, Sweden had 322,574 inhabitants in 2015. We used diagnosis registry, charts, and radiographs of the only city hospital to classify fractures in individuals < 16 years in 2014–2016, and compared these with data from 1950–2006. We used joinpoint regression to analyze time trends and present results as mean annual percentage changes (APC). Differences between peri

https://www.lupop.lu.se/article/time-trends-pediatric-fractures-swedish-city-1950-2016 - 2025-03-15

Combined fracture and mortality risk evaluation for stratifying treatment in hip fracture patients: A feasibility study

Published 9 December 2020 Two academic centers in Lithuania and Turkey participated in this retrospective study conducted between November 2018 and July 2019. A total of 100 consecutive patients (22 males, 78 females; mean age 78.9 years; range, 45 to 100 years) with low energy proximal femur fractures admitted for surgery were included in the study. Fracture Risk Assessment tool (FRAX) and the Se

https://www.lupop.lu.se/article/combined-fracture-and-mortality-risk-evaluation-stratifying-treatment-hip-fracture-patients - 2025-03-15

The rise in the number of long-term survivors from different diseases can slow the increase in life expectancy of the total population Marcus Ebeling, Anna C. Meyer & Karin Modig

Published 10 December 2020 Recent improvements in life expectancy in many countries stem from reduced mortality from cardiovascular disease and cancer above the age of 60. This is the combined result of decreased incidence and improved survival among those with disease. The latter has led to a higher proportion in the population of people with a past history of disease. This is a group with higher

https://www.lupop.lu.se/article/rise-number-long-term-survivors-different-diseases-can-slow-increase-life-expectancy-total - 2025-03-15

Advancing Global Health through Environmental and Public Health Tracking

Published 10 December 2020 Global environmental change has degraded ecosystems. Challenges such as climate change, resource depletion (with its huge implications for human health and wellbeing), and persistent social inequalities in health have been identified as global public health issues with implications for both communicable and noncommunicable diseases. This contributes to pressure on health

https://www.lupop.lu.se/article/advancing-global-health-through-environmental-and-public-health-tracking-0 - 2025-03-15

Creation and implementation of a European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC registry)

Published 11 December 2020 International patient registries are of particular importance for rare disorders, as they may contribute to overcome the lack of knowledge derived from low number of patients and limited awareness of these diseases, and help to learn more about their geographical or population-based specificities, which is relevant for research purposes and for promoting better standards

https://www.lupop.lu.se/article/creation-and-implementation-european-registry-patients-mcardle-disease-and-other-muscle-glycogenoses - 2025-03-15

Phenotypic diversity in an international Cure VCP Disease registry

Published 11 December 2020 Dominant mutations in valosin-containing protein (VCP) gene cause an adult onset inclusion body myopathy, Paget’s disease of bone, and frontotemporal dementia also termed multisystem proteinopathy (MSP). The genotype-phenotype relationships in VCP-related MSP are still being defined; in order to understand this better, we investigated the phenotypic diversity and pattern

https://www.lupop.lu.se/article/phenotypic-diversity-international-cure-vcp-disease-registry - 2025-03-15

Impact of COVID-19 on Online Gambling – A General Population Survey During the Pandemic

Published 12 December 2020 The COVID-19 pandemic may have severe impact on mental health, and concerns have been raised about potentially increased online behavior and possibly increased gambling problems, such as in sports bettors at risk of transfer to even riskier forms of gambling during sports lock-down. Given the need for objective data about gambling behavior during the pandemic, the presen

https://www.lupop.lu.se/article/impact-covid-19-online-gambling-general-population-survey-during-pandemic - 2025-03-15

The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data

Published 12 December 2020 Survival data for pancreatic cancer are usually based on actuarial calculations and actual long-term survival rates are rarely reported. Here we use population-level data from the Surveillance, Epidemiology, and End Results program for patients with microscopically confirmed pancreatic ductal adenocarcinoma diagnosed from 1975 to 2011. A total of 84,275 patients with at

https://www.lupop.lu.se/article/actual-5-year-survivors-pancreatic-ductal-adenocarcinoma-based-real-world-data - 2025-03-15

Disturbance in the oropharyngeal microbiota in relation to antibiotic and proton pump inhibitor medication and length of hospital stay

Published 13 December 2020 The aim of this study was to investigate the appearance of a disturbed oropharyngeal microbiota during hospitalization and explore the patient characteristics that maybe associated with such a disturbance. Oropharyngeal swabs were collected from 134 patients at hospital admission and every 3–4 days thereafter. The samples were cultivated to determine the presence of a di

https://www.lupop.lu.se/article/disturbance-oropharyngeal-microbiota-relation-antibiotic-and-proton-pump-inhibitor-medication-and - 2025-03-15

Daily School Physical Activity Is Associated with Higher Level of Physical Activity Independently of Other Socioecological Factors

Published 13 December 2020 Only one fifth of children aged 11–17 years are physically active for 60 min (min)/day. As physical activity (PA) levels track from childhood to adulthood, it is important to establish healthy PA behavior early in life. This study aims to evaluate whether daily school PA is associated with objectively measured PA independently of other socioecological factors. This study

https://www.lupop.lu.se/article/daily-school-physical-activity-associated-higher-level-physical-activity-independently-other - 2025-03-15

A Novel Method for Quantifying Intestinal Inflammatory Burden in Inflammatory Bowel Disease Using Register Data

Published 14 December 2020 The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aimed to develop and validate a histology score from ESPRESSO using

https://www.lupop.lu.se/article/novel-method-quantifying-intestinal-inflammatory-burden-inflammatory-bowel-disease-using-register - 2025-03-15

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics

Published 15 December 2020 We are living in a multi-omics era of systems epidemiology. Quantitative high-throughput metabolomics and lipidomics have resulted in hundreds of molecular measures for up to tens of thousands of people in multiple cohorts and biobanks. Extensive and complex data create significant challenges for statistical analyses. It would therefore be beneficial, not only for omics

https://www.lupop.lu.se/article/epimetal-open-source-graphical-web-browser-tool-easy-statistical-analyses-epidemiology-and - 2025-03-15