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Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study

Published 23 July 2020 Central arterial stiffness is a surrogate of cardiovascular risk and predicts cardiovascular mortality. Apolipoprotein B lipoproteins are also established cardiovascular risk factors. It is not known whether specific lipoprotein subclasses measured in the Malmö Diet and Cancer Study and previously shown to be associated with coronary heart disease also predict arterial stiff

https://www.lupop.lu.se/article/lipoprotein-particle-predictors-arterial-stiffness-after-17-years-follow-malmo-diet-and-cancer-study - 2025-01-29

Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain

Published 23 July 2020 Excess weight gain throughout adulthood can lead to adverse clinical outcomes and are influenced by complex factors that are difficult to measure in free-living individuals. Metabolite profiling offers an opportunity to systematically discover new predictors for weight gain that are relatively easy to measure compared to traditional approaches. New publication in PLOS ONE

https://www.lupop.lu.se/article/using-metabolite-profiling-construct-and-validate-metabolite-risk-score-predicting-future-weight - 2025-01-29

Daily School Physical Activity from before to after Puberty Improves Bone Mass and a Musculoskeletal Composite Risk Score for Fracture

Published 24 July 2020 This 7.5-year prospective controlled exercise intervention study assessed if daily school physical activity (PA), from before to after puberty, improved musculoskeletal traits. There were 63 boys and 34 girls in the intervention group (40 min PA/day), and 26 boys and 17 girls in the control group (60 min PA/week). We measured musculoskeletal traits at the start and end of th

https://www.lupop.lu.se/article/daily-school-physical-activity-after-puberty-improves-bone-mass-and-musculoskeletal-composite-risk - 2025-01-29

Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden

Published 24 July 2020 Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential ass

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden - 2025-01-29

Injuries and illnesses in Swedish Paralympic athletes—A 52‐week prospective study of incidence and risk factors

Published 25 July 2020 Sports‐related injuries and illnesses in Paralympic sport (SRIIPS) are a concern, but knowledge about the etiology and risk factors is limited. The aim of this study was to describe the annual incidence, type, and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors. New publication in Scandinavian Journal of Medicine & Science in S

https://www.lupop.lu.se/article/injuries-and-illnesses-swedish-paralympic-athletes-52-week-prospective-study-incidence-and-risk - 2025-01-29

Changes in breast density over serial mammograms: A case-control study

Published 25 July 2020 In addition to a breast density category, temporal changes in breast density have gained attention as a dynamic breast cancer risk marker. This case-control study aimed to investigate a potential change in breast density preceding tumor development and the relationship of this potential change to prognostic pathological tumor variables. New publication in European Journal of

https://www.lupop.lu.se/article/changes-breast-density-over-serial-mammograms-case-control-study - 2025-01-29

Social Stratification, Diet Diversity and Malnutrition among Preschoolers: A Survey of Addis Ababa, Ethiopia

Published 26 July 2020 In Sub-Saharan Africa, being overweight in childhood is rapidly rising while stunting is still remaining at unacceptable levels. A key contributor to this double burden of malnutrition is dietary changes associated with nutrition transition. Although the importance of socio-economic drivers is known, there is limited knowledge about their stratification and relative importan

https://www.lupop.lu.se/article/social-stratification-diet-diversity-and-malnutrition-among-preschoolers-survey-addis-ababa-ethiopia - 2025-01-29

The role of professional logics in quality register use: a realist evaluation

Published 27 July 2020 Clinical practice improvements based on quality-register data are influenced by multiple factors. Although there is agreement that information from quality registers is valuable for quality improvement, practical ways of organising register use have been notoriously difficult to realise. The present study sought to investigate the mechanisms that lead various clinicians to u

https://www.lupop.lu.se/article/role-professional-logics-quality-register-use-realist-evaluation-0 - 2025-01-29

Women with fair phenotypes seem to confer a survival advantage in a low UV milieu. A nested matched case control study

Published 27 July 2020 Sun exposure in combination with skin pigmentation is the main determinant for vitamin D status. Human skin color seems to be adapted and optimized for regional sun ultraviolet (UV) intensity. However, we do not know if fair, UV-sensitive skin is a survival advantage in regions with low UV radiation. New publication in PLOS ONE

https://www.lupop.lu.se/article/women-fair-phenotypes-seem-confer-survival-advantage-low-uv-milieu-nested-matched-case-control-study - 2025-01-29

Establishing spatially-enabled health registry systems using implicit spatial data pools: case study – Uganda

Published 28 July 2020 Spatial epidemiological analyses primarily depend on spatially-indexed medical records. Some countries have devised ways of capturing patient-specific spatial details using ZIP codes, postcodes or personal numbers, which are geocoded. However, for most resource-constrained African countries, the absence of a means to capture patient resident location as well as inexistence o

https://www.lupop.lu.se/article/establishing-spatially-enabled-health-registry-systems-using-implicit-spatial-data-pools-case-study-0 - 2025-01-29

A Graphical Catalog of Threats to Validity Linking Social Science with Epidemiology

Published 1 May 2020 Directed acyclic graphs (DAGs), a prominent tool for expressing assumptions in epidemiologic research, are most useful when the hypothetical data generating structure is correctly encoded. Understanding a study’s data generating structure and translating that data structure into a DAG can be challenging, but these skills are often glossed over in training. New publication in E

https://www.lupop.lu.se/article/graphical-catalog-threats-validity-linking-social-science-epidemiology - 2025-01-29

Neck and upper extremity pain in sonographers – a longitudinal study

Published 2 May 2020 Sonographers have reported a high occurrence of musculoskeletal pain for more than 25 years. Assessments of occupational risk factors have previously been based on cross-sectional surveys. The aim of this longitudinal study was to determine which factors at baseline that were associated with neck/shoulder and elbow/hand pain at follow-up. New publication in BMC Musculoskeletal

https://www.lupop.lu.se/article/neck-and-upper-extremity-pain-sonographers-longitudinal-study - 2025-01-29

Correlation without a cause: an epidemiological odyssey

Published 3 May 2020 In the 1980s debate intensified over whether there was a protective effect of high-density lipoprotein cholesterol (HDL-C) or an adverse effect of triglycerides on coronary heart disease (CHD) risk. In a 1991 paper reprinted in the IJE we suggested that the high degree of correlation between the two, together with plausible levels of measurement error, made it unlikely that co

https://www.lupop.lu.se/article/correlation-without-cause-epidemiological-odyssey - 2025-01-29

Duplicate and salami publication: a prevalence study of journal policies

Published 4 May 2020 Duplicate and salami publication are unethical, but are common practices with substantial consequences for science and society at large. Scientific journals are the ‘gatekeepers’ of the publication process. We investigated journal policies on duplicate and salami publication New publicationin International Journal of Epidemiology

https://www.lupop.lu.se/article/duplicate-and-salami-publication-prevalence-study-journal-policies - 2025-01-29

Evidence synthesis for constructing directed acyclic graphs (ESC-DAGs): a novel and systematic method for building directed acyclic graphs

Published 6 May 2020 Directed acyclic graphs (DAGs) are popular tools for identifying appropriate adjustment strategies for epidemiological analysis. However, a lack of direction on how to build them is problematic. As a solution, we propose using a combination of evidence synthesis strategies and causal inference principles to integrate the DAG-building exercise within the review stages of resear

https://www.lupop.lu.se/article/evidence-synthesis-constructing-directed-acyclic-graphs-esc-dags-novel-and-systematic-method - 2025-01-29

Associations between perfluoroalkyl substances and serum lipids in a Swedish adult population with contaminated drinking water

Published 7 May 2020 Exposures to perfluoroalkyl substances (PFAS) have shown positive associations with serum lipids in previous studies. While many studies on lipids investigated associations with perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), there are only a few studies regarding other PFAS, such as perfluorohexane sulfonic acid (PFHxS). The purpose of the current stud

https://www.lupop.lu.se/article/associations-between-perfluoroalkyl-substances-and-serum-lipids-swedish-adult-population - 2025-01-29

A Graphical Description of Partial Exchangeability

Published 8 May 2020 Partial exchangeability is sufficient for the identification of some causal effects of interest. Here we review the use of common graphical tools and the sufficient component cause model in the context of partial exchangeability. We illustrate the utility of single world intervention graphs (SWIGs) in depicting partial exchangeability and provide an illustrative example of whe

https://www.lupop.lu.se/article/graphical-description-partial-exchangeability - 2025-01-29

Analyzing the situation of older family caregivers with a focus on health-related quality of life and pain: a cross-sectional cohort study

Published 9 May 2020 For a significant proportion of the older population, increasing age is associated with health problems and worsening health. Older family caregivers are largely responsible for care of next-of-kin living at home, which impacts their own physical and mental health both positively and negatively. However, evidence is insufficient regarding the health situation of older caregive

https://www.lupop.lu.se/article/analyzing-situation-older-family-caregivers-focus-health-related-quality-life-and-pain-cross - 2025-01-29