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Interest in type 1 diabetes screening is growing as methods improve and new treatments become available to more patients. New research at Lund University demonstrates how screening for autoimmune diseases can be carried out on a large-scale basis. A new treatment that can delay the onset of type 1 diabetes has been approved for use in the United States. If the treatment Teplizumab becomes availabl

https://www.medicine.lu.se/article/new-method-allows-large-scale-screening-autoimmune-diseases - 2025-11-07

Antibodies are the body's superheroes, recognizing and eliminating disease-causing substances. By combining parts from antibodies, researchers at Lund University have designed a hybrid antibody that better stimulates the immune system against both the SARS-CoV-2 virus and streptococcal bacteria. Antibodies can be likened to keys, with antigens as the corresponding locks. Each antibody is uniquely

https://www.medicine.lu.se/article/recipe-great-antibody - 2025-11-07

Heart attack and stroke are common complications of diabetes, as the body's ability to repair and form vessels is impaired. Researchers at Lund University have developed a new substance with the capacity to stimulate vascular repair response and the formation of vessels. In diabetes, the body's ability to repair vascular damage caused by the disease is impaired, which can lead to complications suc

https://www.medicine.lu.se/article/new-peptide-may-reduce-risk-diabetes-complications - 2025-11-07

Filipe Pereira and his research team have discovered a recipe on how to reprogram cancer cells into antigen-presenting dendritic cells, essential for initiating and enhancing anti-tumour immunity. This approach provides a promising strategy for cancer treatment. The goal of the now awarded project is to engineer the "vehicle" to deliver the instruction converting the cells, utilizing RNA vectors f

https://www.medicine.lu.se/article/professor-filipe-pereira-awarded-erc-proof-concept-grant - 2025-11-07

Precision medicine seeks to reduce errors and improve accuracy in medical and health recommendations, but better evidence is needed to fulfil its potential. An international consortium led by Paul Franks at Lund University presents new guidelines that may increase the clinical relevance of precision medicine research. An international consensus report on precision medicine that was published in Na

https://www.medicine.lu.se/article/new-guidelines-aim-increase-accuracy-precision-medicine-research - 2025-11-07

By injecting a solution of nanoparticles around the heart, a temporary heart stimulator self-assembles, which can correct heart arrhythmia in emergency situations with the help of an external power source. After treatment, the electrode spontaneously disappears from the body. The study was conducted on animals. Short facts about the study: arrhythmia // basic research // experimental study // anim

https://www.medicine.lu.se/article/injectable-heart-stimulator-emergency-situations - 2025-11-07

In an infection, there are tens of thousands of peptides that provide a wealth of information about which bacteria have caused the infection and how severe it is. A research team at Lund University has now combined clinical questions with mathematical methods to systematically analyze these peptides. This scientific breakthrough has the potential to transform the diagnosis and treatment of infecti

https://www.medicine.lu.se/article/faster-detection-dangerous-infections - 2025-11-07

There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden. “This has considerable significance for patients wit

https://www.medicine.lu.se/article/no-benefits-24-hour-compared-15-hour-oxygen-therapy - 2025-11-07

Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune system fight cancer. Their approach, now published in the journal Science, could lead to more effective treatments for hard-to-treat cancers. Reprogramming Cancer Cells into Immune Cells Earlier research by the team showed that three special

https://www.medicine.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-11-07

By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for researchers, and it was held in front of an audience of almost 400 students at Helsingborg's Stadsteater on 1 October. In November,

https://www.medicine.lu.se/article/he-won-regional-heat-researcher-grand-prix-now-heading-national-contest-stockholm - 2025-11-07

For the first time, researchers have linked specific frequent defects in sperm to risk of pregnancy complications and negative impacts on the health of the baby. The study from Lund University in Sweden shows that high proportion of father’s spermatozoa possessing DNA strand breaks is associated with doubled risk of preeclampsia in women who have become pregnant by IVF. It also increases the risk

https://www.medicine.lu.se/article/defective-sperm-doubles-risk-preeclampsia - 2025-11-07

It has previously been difficult to identify DNA mutations in sperm, as these changes are rare, and most sequencing techniques have a large margin of error. Now a research study led from Lund University, have conducted a pilot study in which they examined sperm DNA and it’s similarity to mutations in children, using the advanced technique called duplex sequencing. Nearly 80 percent of all new muta

https://www.medicine.lu.se/article/new-method-enables-identification-mutations-sperm - 2025-11-07

A career in science was not on the map for Kári Stefánsson, who aspired to become a writer. But life took another road and the return to Iceland almost three decades ago marked the start of a journey that would revolutionize genetics. Meet this year’s receiver of the Eric K. Fernström Award. "Genetics is the only way to systematically study human nature. So we came to the conclusion that the way t

https://www.medicine.lu.se/article/success-makes-it-difficult-quit - 2025-11-07

Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a pioneering clinical risk prediction algorithm has been developed that splits obesity into 5 separate diagnostic profiles each with contrasting health conseq

https://www.medicine.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-11-07

Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection with diabetes. He will be awarded this year's Medeon stipend on the World Diabetes Day Skåne event in Malmö on November 14. "I hope that my research can contribute to an increased awareness of the importan

https://www.medicine.lu.se/article/praised-research-diabetes-and-dementia - 2025-11-07

In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of new knowledge about type 1 diabetes and how the disease develops. Analysis of the samples will continue with the aim of preventing the disease. Sweden and Finland are the two top countries for incidence rates o

https://www.medicine.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-11-07

Malin Parmar, professor of cellular neuroscience, along with three researchers in Italy and Denmark, has been awarded the prestigious ERC Synergy Grant worth EUR 10 million. The four researchers aim to develop custom-made neurons from stem cells for cell therapies to treat Parkinson’s or Huntington’s disease. Congratulations!“Thank you, it feels really fun and exciting for many reasons! One reason

https://www.medicine.lu.se/article/erc-synergy-grant-awarded-development-custom-made-stem-cell-therapies - 2025-11-07

A research team at Lund University in Sweden has discovered a certain type of cells – foam cells – in patients with the aggressive brain tumour glioblastoma. It has been shown how these cells accelerate the cancer’s growth and that this can be successfully inhibited using a drug developed for arteriosclerosis. Glioblastoma affects around 500 Swedes every year and is the most common and most aggres

https://www.medicine.lu.se/article/foam-cells-brain-tumours - 2025-11-07

After 20 years of research on gene therapy and the rare blood disease, Diamond-Blackfan Anemia, DBA, researcher Johan Flygare had reached a point where he and his colleagues had done everything they could in the lab. Even though they had proof of concept their gene therapy would work, engaging companies had been difficult. Then, in 2021, he received an e-mail. LONGREAD. The message came from Ameri

https://www.medicine.lu.se/article/science-start-developing-gene-therapy-rare-blood-disorder - 2025-11-07

Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. However, bioelectronic treatment is not without complications. Researchers at Lund University in Sweden have taken another step forward by developing a refined method to create detailed and tissue-friendly bioelectronics. In a study published in Advanced Science

https://www.medicine.lu.se/article/using-light-create-bioelectronics-inside-body - 2025-11-07