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Reported normal values and weighted means for commonly used echocardiography pulsed Doppler and tissue Doppler measurements

Pulsed Doppler (PW) and tissue Doppler imaging (TDI) measurements are part of every echocardiography examination for evaluation of left ventricular (LV) diastolic function and filling pressure. The purpose of this study was to summarize published data on normal values for PW and TDI measurements. A PubMed search was performed on the 10th of October 2016 to identify relevant articles. Studies were

Prospective temporal validation of mathematical models to calculate risk of endometrial malignancy in patients with postmenopausal bleeding

Objectives: To validate prospectively five mathematical models published in 2007 for calculating the risk of endometrial malignancy in a defined high-risk group of patients with postmenopausal bleeding and sonographic endometrial thickness≥4.5mm. Methods: Of 1012 consecutive patients, 379 fulfilled our inclusion criteria, which were the same as those of the original study in which the models were

Housing accessibility problems for people with Parkinson's disease

Objectives: Promoting accessible housing for all citizens is high on the political agenda. Knowledge is, however, limited regarding housing accessibility problems for people with Parkinson's disease (PD). The objectives were to investigate housing accessibility problems among people with PD at different stages of disease severity and to analyze the potential impact of improved functional ability o

Heparin-binding protein : A key player in the pathophysiology of organ dysfunction in sepsis

Infectious diseases remain a major health problem, and sepsis and other severe infectious diseases are common causes of morbidity and mortality. There is a need for clinical and laboratory tools to identify patients with severe infections early and to distinguish between bacterial and nonbacterial conditions. Heparin-binding protein (HBP), also known as azurocidin or cationic antimicrobial protein

Predictors of incidental gallbladder cancer in patients undergoing cholecystectomy for benign gallbladder disease : Results from a population-based gallstone surgery registry

Background: Gallbladder cancer is a rare neoplasm with a poor prognosis. Early diagnosis and correct treatment strategy is important. The aim of this study was to identify predictors for incidental gallbladder cancer. Methods: Data from cholecystectomies registered in the nationwide Swedish Register for Gallstone Surgery between 2007 and 2014 were analyzed for incidental gallbladder cancer. Exclus

How does distance to urban centres influence necessity and opportunity-based firm start-ups?

This paper seeks to understand how distance to urban centres influences necessity and opportunity-based firm start-ups. The results show that closeness to urban centres is not necessarily beneficial for firm start-ups. On the contrary, regions further away from urban centres of any size experience more firm start-ups. One explanation of this result is that regions experience spatial protection fro

A model library for simulation and benchmarking of integrated urban wastewater systems

This paper presents a freely distributed, open-source toolbox to predict the behaviour of urban wastewater systems (UWS). The proposed library is used to develop a system-wide Benchmark Simulation Model (BSM-UWS) for evaluating (local/global) control strategies in urban wastewater systems (UWS). The set of models describe the dynamics of flow rates and major pollutants (COD, TSS, N and P) within t

Synthesis and Characterization of Cyclopentadithiophene Heterofulvenes : Design Tools for Light-Activated Processes

The development of new materials for solar-to-energy conversion should consider stability, ease of fabrication, and beneficial photophysical properties. In this context, a set of novel π-conjugated building blocks, with phospha- and arsaalkenes possessing a unique dithienyl annulated heterofulvenoid core, have been prepared as air- and moisture-stable sensitizers. These compounds unify electron-do

Investigations of microwave stimulation of turbulent flames with implications to gas turbine combustors

Efficient and clean production of electrical energy and mechanical (shaft) energy for use in industrial and domestic applications, surface- and ground transportation and aero-propulsion is currently of significant general concern. Fossil fuels are mainly used for transportation and aero-propulsion, but also for power generation. Combustion of fossil fuels typically give rise to undesired emissions

Fission dynamics with microscopic level densities

We present a consistent framework for treating the energy and angularmomentum dependence of the shape evolution in the nuclear fission. It combines microscopically calculated level densities with the Metropolis-walk method, has no new parameters, and can elucidate the energy-dependent influence of pairing and shell effects on the dynamics of warm nuclei.

The influence of voice quality on sentence processing and recall performance in school-age children with normal hearing

Previous findings suggest that working memory capacity (WMC) is influenced by a dysphonic voice quality. The present study examines the influence of voice quality on sentence processing and word recall in a working memory task. Fifty-seven children (8:1–9:1 years old) with normal hearing participated. Working memory capacity (WMC) was assessed using a competing language processing task (CLPT) whic

Wholegrain oat diet changes the expression of genes associated with intestinal bile acid transport

Scope: The molecular mechanisms underlying the cholesterol-lowering properties of oats are only partly known. To study possible pathways involved, we investigated gene expressions in the liver and small intestine of mice fed oats. Method and results: Cholesterol and bile acids were analyzed in plasma and feces from LDL-receptor deficient (LDLr-/-) mice fed Western diet with wholegrain oats. A tran

Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding

Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes UNC13D, STX11 and STXBP2 have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients heterozygou

Cholesterol, cholesterol-lowering medication use, and breast cancer outcome in the BIG 1-98 study

Purpose Cholesterol-lowering medication (CLM) has been reported to have a role in preventing breast cancer recurrence. CLM may attenuate signaling through the estrogen receptor by reducing levels of the estrogenic cholesterol metabolite 27-hydroxycholesterol. The impact of endocrine treatment on cholesterol levels and hypercholesterolemia per se may counteract the intended effect of aromatase inhi

Toileting behavior and urinary tract symptoms among younger women

Introduction and hypothesis: Irregular or infrequent voiding due to avoiding school toilets can contribute to a number of urinary problems among school children. There is, however, a lack of studies on younger women. The aim of this study was to investigate toileting behavior and the correlation to lower urinary tract symptoms (LUTS) among young women (age 18–25 years). A further aim was to valida