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Variation in Patient-Reported Outcomes in Young and Old Patients Up to 4 to 6 Years After Arthroscopic Partial Meniscectomy

Objective: To assess the variation in changes in patient-reported outcomes 4 to 6 years after arthroscopic partial meniscectomy (APM).Design:Prospective cohort study.Setting:Orthopedic departments at public hospitals.Patients:Patients (n = 447) from the Knee Arthroscopy Cohort Southern Denmark undergoing APM.Interventions:All patients underwent APM.Main Outcome Measures:Change in KOOS4scores from

Patients’ Health Experiences of Post COVID-19 Condition—A Qualitative Study

Patients who suffer from long-term symptoms of COVID-19, described as post COVID-19 condition, are a new and large group of patients. There is a lack of knowledge concerning health experiences in this patient group. The aim of this study was to explore patients’ health experiences of post COVID-19 condition. Data collection was performed through 14 semi-structured interviews. The qualitative conte

High risk of developing dementia in Parkinson’s disease : a Swedish registry-based study

Dementia have substantial negative impact on the affected individual, their care partners and society. Persons living with Parkinson’s disease (PwP) are also to a large extent living with dementia. The aim of this study is to estimate time to dementia in PD using data from a large quality register with access to baseline clinical and patient reported data merged with Swedish national health regist

Ganglioglioma surgery associated with postoperative status epilepticus : a case report

Background: Gangliogliomas are brain tumors associated with drug-resistant focal epilepsy. In most cases, seizures improve after surgical treatment. It is still not concluded to what extent the lesion itself or the perilesional area contributes to the epileptogenicity. Case presentation: In the case presented in this report, the patient, a 24-year-old Caucasian male, developed a refractory status

Postprandial Responses to a Standardised Meal in Hypertension : The Mediatory Role of Visceral Fat Mass

Postprandial insulinaemia, triglyceridaemia and measures of inflammation are thought to be more closely associated with cardiovascular risk than fasting measures. Although hypertension is associated with altered fasting metabolism, it is unknown as to what extent postprandial lipaemic and inflammatory metabolic responses differ between hypertensive and normotensive individuals. Linear models adjus

“It is coming home to Rome” : social engagement and creativity in reactions to England national football team losing Euro 2020

PurposeThe purpose of this commentary paper is to analyze the burst of joy experienced by global football fans when England lost the final match during the Euro 2020 against Italy.Design/methodology/approachThe author worked with netnography (Internet ethnography), gathering material from the internet.FindingsThe author would consider the emotional explosion as a creative expression that was possi

Ab initio thermo-elasticity of 𝛿-MH𝑥 (M=Zr, Ti)

In the present work, we report the results of a systematic ab initio study of the thermo-elastic properties of δδMH1.5 (M=Zr, Ti). This investigation serves three purposes: (i) Elucidate the fully anisotropic temperature dependent elastic constants of hydrides, (ii) address discrepancies in thermal expansion data reported in the literature and (iii) provide input data for thermodynamic-based phase

Axonal degeneration and amyloid pathology predict cognitive decline beyond cortical atrophy

Background: Cortical atrophy is associated with cognitive decline, but the association is not perfect. We aimed to identify factors explaining the discrepancy between the degree of cortical atrophy and cognitive decline in cognitively unimpaired elderly. Methods: The discrepancy between atrophy and cognitive decline was measured using the residuals from a linear regression analysis between change

Effects of conventionally treated and ozonated wastewater on the damselfly larva oxylipidome in response to on-site exposure

Pharmaceutical residues discharged through insufficiently treated or untreated wastewater enter aquatic environments, where they may adversely impact organisms such as aquatic invertebrates. Ozonation, an advanced wastewater treatment technique, has been successfully implemented to enhance the removal of a broad range of pharmaceuticals, however diverse byproducts and transformation products that

Flame heights and charring on a particle board – An experimental study

Vertically oriented particle-board samples were exposed to external venting flames to study the fire spread and charring behaviour along a timber façade. Variation in flame height and the height, volume, area, density, and depth of the char layer were studied to determine the impact of heat-release rate and experiment duration. There was a peak flame height after which the flame returned to steady

Copy number variants suggest different molecular pathways for the pathogenesis of bladder exstrophy

Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11-duplications detected in about 2%–3% of all patients. Some genes are implicated like the LZTR1, ISL1, CELSR3, and the WNT3 genes, but most are not explained m

Orbital-selective Mott and Peierls transition in H xVO2

Materials displaying metal-insulator transitions (MITs) as a function of external parameters such as temperature, pressure, or composition are most intriguing from the fundamental point of view and also hold high promise for applications. Vanadium dioxide (VO2) is one of the most prominent examples of MIT having prospective applications ranging from intelligent coatings, infrared sensing, or imagi

Opportunities and barriers for occupational engagement among residents in supported housing

Opportunities and barriers for occupational engagement among residents in supported housing. Background: Research shows that people with psychiatric disabilities view supported housing (SH) as a possibility for social contact, but also as entailing a risk of deprived self-determination. There is, however, little research on the target group’s engagement in everyday occupations. Aim: To explore SH

Stable ocean redox during the main phase of the Great Ordovician Biodiversification Event

The Great Ordovician Biodiversification Event (GOBE) represents the greatest increase in marine animal biodiversity ever recorded. What caused this transformation is heavily debated. One hypothesis states that rising atmospheric oxygen levels drove the biodiversification based on the premise that animals require oxygen for their metabolism. Here, we present uranium isotope data from a Middle Ordov

Seasonal variation in temperature sensitivity of bacterial growth in a temperate soil and lake

Faster bacterial biomass turnover is expected in water compared to soil, which would result in more rapid community adaption to changing environmental conditions, including temperature. Bacterial community adaptation for growth is therefore predicted to have larger seasonal amplitudes in lakes than in soil. To test this prediction, we compared the seasonal variation in temperature adaptation of ba

The 2022 International Society for Stem Cell Research (ISSCR) Annual Meeting : Celebrating 20 Years of Achievements

Last June, the stem cell community came together to celebrate the 20th anniversary of the International Society for Stem Cell Research (ISSCR), one of the leading organizations in the field. The hybrid event mixed a varied program filled with plenary talks, concurrent track sessions, poster presentations, exhibit booths, and plenty of opportunities to enhance stem cell research through bonding bet

Past, Present, and Future of Direct Cell Reprogramming

Budding off from the broader developmental biology and stem cell research fields, cellular reprogramming is now established as a prominent discipline in its own right. Direct cell reprogramming is defined as the cell fate conversion of a somatic cell toward another identity without a pluripotent intermediate state. In addition to the opportunity for mechanistic dissection of lineage commitment in