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Carbon exchange in boreal ecosystems: upscaling and the impacts of natural disturbances

Boreal forests and peatlands are globally significant carbon stores but they are threatened by rising air temperatures and changes in precipitation regimes and the frequency of natural disturbances. Predicting how the boreal biome will respond to climate change depends on being able to accurately model and upscale the greenhouse gas fluxes between these ecosystems and the atmosphere. This thesis f

Denitrification by benthic foraminifera and their contribution to N-loss from a fjord environment

Oxygen and nitrate availabilities impact the marine nitrogen cycle at a range of spatial and temporal scales. Here, we demonstrate the impact of denitrifying foraminifera on the nitrogen cycle at two oxygen and nitrate contrasting stations in a fjord environment (Gullmar Fjord, Sweden). Denitrification by benthic foraminifera was determined through the combination of specific density counting per

Overarching policy framework for product life extension in a circular economy—A bottom‐up business perspective

Public policy has a critical role to play in supporting business actors towards their transition to more sustainable and less resource‐intensive practices within the context of a Circular Economy (CE). The European Union (EU) CE Action Plan sets a special focus on the role of business in adopting and promoting circular economic principles in their operations, and thus leading the transition toward

Development of acoustically isolated extracellular plasma vesicles for biomarker discovery in allogeneic hematopoietic stem cell transplantation

Background: Infection and graft-versus-host disease (GvHD) are the major causes for mortality and morbidity of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Plasma-derived extracellular vesicles (EVs) contain disease-related proteins, DNAs and RNAs, and have recently been suggested as potential biomarker candidates for transplantation complications. However, EV isolation from sma

Neuroligin-1 in brain and CSF of neurodegenerative disorders : investigation for synaptic biomarkers

Synaptic pathology is a central event in Alzheimer’s disease (AD) and other neurodegenerative conditions, and investigation of synaptic proteins can provide valuable tools to follow synaptic dysfunction and loss in these diseases. Neuroligin-1 (Nlgn1) is a postsynaptic cell adhesion protein, important for synapse stabilization and formation. Nlgn1 has been connected to cognitive disorders, and spe

An experimental and kinetic modeling study on the laminar burning velocity of NH3+N2O+air flames

In the present work, the laminar burning velocities of the NH3+N2O+air flames were measured using the heat flux method at 1 atm and 298 K, with varied equivalence ratios and N2O mixing ratios. For the mixing ratio N2O/(N2O+air) = 0.5, a full range of equivalence ratios was covered. Moreover, at three equivalence ratios an extended range of mixing ratios was investigated. The laminar burning veloci

Gene therapy for infantile malignant osteopetrosis : review of pre-clinical research and proof-of-concept for phenotypic reversal

Infantile malignant osteopetrosis is a devastating disorder of early childhood that is frequently fatal and for which there are only limited therapeutic options. Gene therapy utilizing autologous hematopoietic stem and progenitor cells represents a potentially advantageous therapeutic alternative for this multisystemic disease. Gene therapy can be performed relatively rapidly following diagnosis,

Gender differences in willingness to compete : The role of public observability

A recent literature emphasizes that gender differences in the labor market may in part be driven by a gender gap in willingness to compete. However, whereas experiments in this literature typically investigate willingness to compete in private environments, real world competitions often have a more public nature, which introduces potential social image concerns. If such image concerns are importan