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The final chapter presents a summary of the key themes and insights from the Elgar Handbook as workshopped in Dublin in October 2023 and developed by the named authors. Health system resilience is a potent and useful concept which has shown a versatility and appeal across a range of health system crises. Nevertheless, it still needs to gain maturity with key challenges around understanding and mea
This is the second of three chapters on diffusion MRI acquisition for tractography. This chapter covers image formation, which is largely independent of the creation of diffusion contrast (Chapter 6). The Stejskal-Tanner diffusion experiments in the 1960s were bulk NMR measurements of diffusion; the addition of spatial localization, i.e., imaging, would follow decades later. The excitation and rea
Many problems in computer vision can be formulated as geometric estimation problems, i.e. given a collection of measurements (e.g. point correspondences) we wish to fit a model (e.g. an essential matrix) that agrees with our observations. This necessitates some measure of how much an observation 'agrees' with a given model. A natural choice is to consider the smallest perturbation that makes the o
Analyzing microstructural properties projected along white matter pathways derived from diffusion magnetic resonance imaging (MRI) has become increasingly popular in recent years. Along-streamline profiling based on diffusion MRI tractometry is a framework that maps summary measures of the diffusion data (e.g., fractional anisotropy) at multiple points along a given pathway, resulting in a so-call
This is the third of three chapters on diffusion MRI acquisition for tractography. Tractography is performed extensively in the in vivo adult brain, and sequences used for the in vivo adult brain have been covered in detail in Chapter 7. However, tractography is also performed in ex vivo human brain, in both the in vivo and ex vivo animal brain of various nonhuman species, in the human brain durin
Becoming couture is the first book to examine the history of the Italian fashion industry during the global transition brought about by the Second World War. It draws on a wide range of primary sources, some of them newly unearthed, to demonstrate that the Italian fashion industry in the Republican era continued to rely on business practices and professionals established during Fascism. Analysing
As gene therapy for haemophilia is now licensed in Europe, and the hub and spoke approach is widely promoted for its delivery and follow-up, it is essential that people with haemophilia (PwH) who are eligible and opt to have this treatment are enabled to obtain the maximum benefit. Ensuring the pathway that makes up the patient gene therapy journey is effective is key to achieving this. EAHAD and
This review deals with the production of oxygen by photo-oxidation of water, which is a topic fitting a journal devoted to oxygen. Most of the present biosphere, including mankind, depends on oxygen. Elucidating the mechanism is of importance for solving the present energy crisis. Photosynthesis evolved in bacteria, first in a form that did not produce oxygen. The oxygen-producing version arose wi
IMPORTANCE: Recent studies suggest standard reference intervals for serum free light chains (FLC) are inaccurate and that this problem can only be partially remedied by using separate reference intervals for individuals with impaired kidney function. This decreases the utility of FLC testing in the clinical evaluation and follow-up of plasma cell disorders, particularly affecting the diagnosis of
OBJECTIVES: Short time to positivity (TTP) has been proposed as a prognostic indicator in bloodstream infection (BSI) but results have been conflicting. The aim of this study was to explore the association between TTP and disease severity, using non-linear models.METHODS: This population-based retrospective study included all blood cultures in southern Sweden from 2021 to 2023. Using healthcare da
Introduction: Some children may witness their grandparents or great-grandparents spending their final days in a nursing home, while others have peers with older relatives living in nursing homes. Children learn about ageing through experience and exposure, where picture books can also shape their perceptions and attitudes toward older adults residing in nursing homes.Aim: To explore the underlying
After a long period of being constructed as anonymous administration complexes, first instance courts are once again being built as emblematic elements of the city, designed by renowned architects and rising up on central plots adjacent to train stations, headquarter buildings and exclusive residential areas. This is happening at a time of centralisation, upsizing and property privatisation, and w
Isoprene is a reactive hydrocarbon emitted to the atmosphere in large quantities by terrestrial vegetation. Annual total isoprene emissions exceed 300 Tg a−1, but emission rates vary widely among plant species and are sensitive to meteorological and environmental conditions including temperature, sunlight, and soil moisture. Due to its high reactivity, isoprene has a large impact on air quality an
Polarized fluorescence microscopy is a valuable tool for measuring molecular orientations in biological samples, but techniques for recovering three-dimensional orientations and positions of fluorescent ensembles are limited. We report a polarized dual-view light-sheet system for determining the diffraction-limited three-dimensional distribution of the orientations and positions of ensembles of fl
This study analyzes the transition to mechanized forest management and the implementation of sustainable-yields forestry in Sweden during the 1950s and 1960s. The objective is to produce insights that are relevantfor policymakers working with forests and the climate transition today. The analysis focuses on how the Swedish National Association of Forest Owners’ Associations (SSR)—an association or
Abstract in French:L’article examine les dix fables en prose que l’auteur suédois August Strindberg a écrites en français pendant les années 1880. L’analyse se concentrera sur trois aspects de ces textes : le contexte de leur création et publication, leur statut générique et la vision qu’ils véhiculent sur la relation entre l’être humain et son animalité. L’article montre que Strindberg a renouvelL’article examine les dix fables en prose que l’auteur suédois August Strindberg a écrites en français pendant les années 1880. L’analyse se concentrera sur trois aspects de ces textes: le contexte de leur création et publication, leur statut générique et la vision qu’ils véhiculent sur la relation entre l’être humain et son animalité. L’article montre que Strindberg a renouvelé le genre de la fab
From the chapter "Introduction and Background": The pilot phase of the National Urban Policy Programme (NUPP): “Developing NUP and Smart City Strategies in Iran” started in 2017 in collaboration between UN-Habitat, Republic of Korea, in three pilot countries of Niger, Myanmar, and Islamic Republic of Iran. It aimed to develop National Urban Policies and Smart City Strategies in Iran and to offer a
