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Pharmaceutical company promotional payments to English general practices: : longitudinal study

BACKGROUND: General practices have been a long-standing focus of pharmaceutical promotion, but their financial relationships with pharmaceutical companies remain understudied.AIM: Examine pharmaceutical company payments to general practices in England from 2015-2022, focusing on changing patterns of payments and what this reveals about companies' marketing.DESIGN & SETTING: Descriptive analysi

Accident data and records

Accident data analysis is the common basis for any decision-making process on traffic safety strategies and management. The quality of the data, in terms of completeness (accuracy and precision of information about accidents) and coverage (severity of accidents recorded, but also the level of accident reporting or underreporting), is always a concern because it can lead to wrong decisions. An acci

Accident modelling : An overview

The goal of this chapter is to provide an overview of key concepts related to modelling accident frequency, considering the random nature of traffic accidents. This includes topics such as the expected number of accidents (the 'true' yet unobserved measure of safety), regression-to-the-mean (RTM) and the safety-in-numbers phenomenon, which were briefly introduced in the chapter on accident data. T

Mixed Logit Model and Classification Tree to Investigate Cyclists Crash Severity

Growing concerns about emissions, urban traffic congestion, and the promotion of an active lifestyle are inducing more people to choose bike for their daily commute. The increase in bike usage underscores the need for improving the cyclist’s safety. Our study examined the 72 363 cyclist crashes that occurred in Great Britain in the period 2016-2019 with the objective of (1) examining how various f

A Hybrid Structural Equation Modeling and Fuzzy-set Qualitative Comparative Analysis Framework for Using Limited Samples to Relate Cycling Performance to Behavioral Traits

The objective of this investigation was to explore a hybrid application of Structural Equation Modelling (SEM) and Fuzzy-set Qualitative Comparative Analysis (FsQCA) to assess the impact of safety-related behavioural traits on the performance of bicyclists using a limited sample of data as a case study. These behavioural characteristics of cyclists are fundamental when specific cyclist groups are

The Crowd, the Press and the Mediated Public : Intramural Executions in Sweden, 1879-1910

This essay is the first systematic study of intramural executions in Sweden. It examines how intramural executions were introduced, and what effects it had on the publicity of executions. All intramural executions 1879‒1910 are studied. The essay presents three notable findings. First, that the aim of the introduction of intramural executions was not to exclude spectators per se, but to exclude wo

The Carba Mix—In Vitro Investigations of Potential Cocktail Effects in Patch Tests With Rubber Allergens

Background: The carba mix is used to screen rubber chemical allergy and consists of three rubber sensitising chemicals: 1% (w/w) zinc diethyldithiocarbamate (ZDEC), 1% (w/w) zinc dibutyldithiocarbamate (ZDBC) and 1% (w/w) 1,3-diphenylguanidine (DPG), all in petrolatum. However, carba mix patch test results can be difficult to interpret, which may be linked to so-called ‘cocktail’ effects. Objectiv

A farm typology approach for targeted policy responses: The case of pastoral and agro-pastoral households in West Pokot County, Kenya

Most agricultural and food policies often overlook diversity of farming households, resulting in generalized and ineffective interventions. Recognizing changing and diverse characteristics of farm types is therefore critical. Using data from 502 households in West Pokot County, Kenya, we employ principal component and cluster analyses to create farm typologies to guide targeted policy intervention

Molecular recognition polymer microspheres and nanoparticles for nonseparation assays: the Mosbach imprint

Synthesis of molecularly imprinted polymer microspheres using precipitation polymerization was first reported in 1999 in Lund. The synthetic approach attracted great interest for molecular imprinters worldwide due to its simplicity. Following the initial demonstration of feasibility for material synthesis, imprinted polymer microspheres were found to exhibit good colloidal stability qualifying for

Recapturing Life : Virtual Peer-Based Psychological Support for Adolescent and Young Adult Cancer Survivors Delivered in the Community

Purpose: Adolescent and young adult (AYA) cancer survivors have unique psychological needs and require tailored support, as they transition from hospital settings following cancer treatment. This study aimed to evaluate the safety and clinical effectiveness of the online "Recapture Life" program to improve AYA aged survivors' psychological adjustment in early cancer survivorship. Methods: The inte

Identification of gut microbiome signatures and metabolites associated with albuminuria in type 2 diabetes

CONTEXT: Type 2 diabetes is a growing global concern with serious complications, including kidney damage and cardiovascular morbidity and mortality. Monitoring albuminuria, which is associated with these complications, is crucial in optimal diabetes management. Gut microbiota composition has been suggested to impact albuminuria, but large studies with granular data are lacking.METHODS: We investig

The ‘Good Samaritan’ : The effects of corporate conflict engagement on public satisfaction and their behavioral intentions

In a time marked by rising geopolitical tensions and societal conflicts, the traditional corporate emphasis on maximizing shareholder value is increasingly evolving towards a more public-oriented approach that includes societal and ethical considerations. Should organizations invest in activities that are not their primary responsibilities? Based on conflict management, corporate social responsibi

“Nazis, I hate these guys”: Indiana Jones as an antifascist memetic icon

Indiana Jones’ staunch anti-Nazism and the franchise’s satirical belittling and ridicule of the Third Reich render its protagonist an antifascist memetic icon. While considerable attention has been devoted to the digital media landscape of the right, less emphasis is given to left-wing movements and memetic warfare. Through analysis of humorous representations of German Nazis in the films, where N

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Trademarks increasingly serve as indicators of product innovation and broader industry shifts, encompassing a wide range of innovation activities and soft innovations often overlooked by patents. However, research on the relationship between trademarks and innovation remains in its early stages, with a lack of exploration into China's soft innovation from the trademark perspective. This paper addr

Transcriptomic Analysis Reveals Key Pathways Influenced by HIV-2 Vpx

Viral protein X (Vpx) is a unique accessory protein encoded by the genome of the human immunodeficiency virus type 2 (HIV-2) and lineages of the simian immunodeficiency virus of sooty mangabeys. So far, counteracting the cellular restriction factor SAMHD1 and mediating the efficient translocation of viral pre-integration complex have been recognized as key functions of Vpx; however, a thorough exp

Fire Risks in Using Paraffin as Neutron Radiation Shielding Material

Safety in general and fire safety in particular are key concerns in neutron-based research facilities, and the choice of the material that is used to stop neutron radiation is critical in this respect. Borated paraffin has been used at existing research facilities and could potentially be used at new facilities. However, a literature search resulted in very little information about the fire proper

“It is very convenient when it works – successes and challenges with welfare technology” - a qualitative study

Welfare technology (WT) use is increasingly advocated to facilitate aging in place. However, it remains unclear how older adults and homecare staff perceive these digital technologies in practice. This qualitative study investigated the ways in which current WT either facilitated or fell short in supporting older adults in their daily lives and homecare staff at work. Four key themes were develope