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Higher plasma IL-6 and PTX3 are associated with worse survival in left heart failure with pulmonary hypertension

Introduction: Left heart failure (LHF) is commonly complicated by pulmonary hypertension (PH), increasing morbidity and mortality. The present study aimed to evaluate the prognostic value of inflammatory proteins in LHF with PH (LHF-PH). Materials and methods: The levels of 65 plasma proteins, analysed with proximity extension assay, were compared between healthy controls (n = 20), patients with L

The Role of Social Norms in Reducing Corruption in Education : A Case Study of Schools in Hanoi-Vietnam

This research report presents empirical findings from an ethnographic study of the role of informal social norms in reducing corruption in public and private schools in Hanoi. The study begins by building a theoretical framework that inculcates the significance of local informal social norms in analysing/understanding corruption and designing counteraction strategies, especially at the sub-nationa

Age-stratified comparison of prognosis in cardiac resynchronization therapy with or without prophylactic defibrillator for non-ischemic cardiomyopathy – a nationwide cohort study

Background and aimsPrior studies have suggested that the benefit from primary preventive defibrillator treatment for patients with non-ischemic cardiomyopathy primarily, treated with cardiac resynchronization therapy, may be age-dependent. We aimed to compare age-stratified mortality rates and mode of death in patients with non-ischemic cardiomyopathy who are treated with either primary preventive

Gas-Phase Anion Exchange for Multisegment Heterostructured CsPb(Br1xClx)3 Perovskite Nanowires

Metal-halide perovskites (MHPs) are promising as active optoelectronic materials for a diverse range of devices. Anion exchange is a post-growth modification of MHP materials that allows tuning of the band gap and crystal structure by exposure to alternative halides, normally using solution methods. Here, low temperature gas-phase anion exchange for the conversion of CsPbBr3 nanowires (NW) into Cs

In Vivo Profiling of the Vascular Cell Surface Proteome in Murine Models of Bacteremia

Vascular dysfunction is a hallmark of systemic inflammatory responses such as bacterial sepsis. The luminal surface of the blood vessels is coated with a dense layer of glycans and proteoglycans, collectively known as the glycocalyx. Surface associated glycoproteins of endothelial origin, or derived from pericytes, intravascular leukocytes, and plasma, are other important components of the glycoca

Measuring Niche-Associated Metabolic Activity in Planktonic and Biofilm Bacteria

Most pathobionts of the respiratory tract form biofilms during asymptomatic colonization to survive and persist in this niche. Environmental changes of the host niche, often resulting from infection with respiratory viruses, changes of the microbiota composition, or other host assaults, can result in biofilm dispersion and spread of bacteria to other host niches, resulting in infections, such as o

Areas of high conservation value support specialist forest birds

Scientists have deemed existing protected areas in European forests insufficient to halt and reverse biodiversity loss resulting from ongoing intensification of management. In Sweden, protected areas are therefore complemented with the so-called areas of high conservation value (AHCVs), that is, landscapes encompassing both protected and assumed biodiversity-valuable areas as well as surrounding l

Ankle-foot orthoses among children with cerebral palsy : a cross-sectional population-based register study of 8,928 children living in Northern Europe

BACKGROUND: Cerebral palsy (CP) is an umbrella term where an injury to the immature brain affects muscle tone and motor control, posture, and at times, the ability to walk and stand. Orthoses can be used to improve or maintain function. Ankle-foot orthoses (AFOs) are the most frequently used orthoses in children with CP. However, how commonly AFOs are used by children and adolescents with CP is st

Breaking down and making up - a lens for conversing with compilers

This paper proposes a ‘tool for thinking with’: that we can describe the interaction between people and computers, and especially people and developer tools, as a form of conversation. We outline this perspective, construct a work in progress analytical frame, and use it to talk about a couple of different examples and draw implications for future work.

Disinformation

Disinformation re-emerged in the 21st century as a public concern and professional challenge for actors seeking to navigate the new political and information landscape. This has led to a growing discussion among researchers on how disinformation relates to PD theory and practice. This chapter argues that disinformation comes with a set of opportunities for PD that open new perspectives to unresolv

Chemistry diagnostics for monitoring

Chemically sensitive diagnostics are indispensable to unravel reactive processes in combustion and beyond, to understand their development in time and space and to monitor the reaction progress under the conditions of interest. A multitude of techniques is available that may provide species composition together with other process-controlling variables as a function of the reaction environment. Ana

Effects of task constraint on action dynamics

The actualization of action possibilities (i.e., affordances) can often be accomplished in numerous ways. For instance, an individual could walk over to a rubbish bin to drop an item in or throw the piece of rubbish into the bin from some distance away. The aim of the current study was to investigate the action dynamics that emerge from such under-constrained task or action spaces using an object

Route selection and obstacle avoidance with a short-range haptic sensory substitution device

The design of Sensory Substitution Devices (SSDs) often relies on the belief that the information supplied by the devices should allow the construction of spatial mental representations on the basis of which routes are planned. This study, in contrast, illustrates that navigation using an SSD can be conceived as an on-line, dynamic process, without the need for establishing a predefined plan or mo

Media & Mediation in the Eighteenth Century

While eighteenth-century print media in essence rested on the same technical apparatus as previous centuries – letterpress printing, woodcuts, and intaglio prints – the growth in quantity created a media revolution. The effect was a qualitative shift in terms of literacy, growth of newspapers, the spread of images, and distribution of knowledge, but also of misinformation and propaganda. In this v