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Complex formed in the system hydrophobically modified polyethylene glycol/methylated alpha-cyclodextrin/water. An NMR diffusometry study

In aqueous solutions hydrophobically modified polyethylene glycol (HM-PEG) forms a transient polymer network held together by intermolecular hydrophobic associations. In the present investigation we have used NMR-diffusometry to study how the addition of methylated alpha-cyclodextrin (M-alpha-CD) influences the polymer network. The addit on of M-alpha-CD resulted in an increased mean self-diffusio

Antigen presentation capacity and cytokine production by murine splenic dendritic cell subsets upon Salmonella encounter.

Salmonella typhimurium is an intracellular bacterium that replicates in the spleen and mesenteric lymph nodes (MLN) of orally infected mice. However, little is known about the Ag presentation and cytokine production capacity of dendritic cells (DC), particularly CD8alpha(+), CD8alpha(-)CD4(-), and CD8alpha(-)CD4(+) DC, from these organs in response to SALMONELLA: Infection of purified splenic DC w

Complexes between activated protein C and protein C inhibitor measured with a new method: comparison of performance with other markers of hypercoagulability in the diagnosis of deep vein thrombosis

A first clinical evaluation has been made of the performance of a newly devised immunofluorometric assay for measuring plasma concentrations of activated protein C (APC) in complex with protein C inhibitor (PCI). The method was compared with testing for other markers of hypercoagulability in a case-control study comprising 123 patients with clinical suspicion of deep vein thrombosis (DVT). The dia

Seasonal changes of mechanisms maintaining clear water in a shallow lake with abundant Chara vegetation

The study is based on monitoring data on the seasonal variation during four (1996-1999) vegetation periods, as well as long-term summer data on submerged vegetation, nutrients, light, phyto-plankton and zooplankton in Lake Krankesjon, a shallow, calcium-rich, moderately eutrophic take in southern Sweden. The lake has been in the clear water state with abundant submerged vegetation since the end of

Frequency-Domain Analysis of Linear Time-Periodic Systems

In this report we study how a time-varying system with a time-periodic integral kernel (impulse response), g(t,\tau)=g(t+T,\tau+T), can be expanded into a sum of essentially time-invariant systems. This allows us to define a linear frequency response operator for periodic systems, called the Harmonic Transfer Function (HTF). The HTF is a direct analog of the transfer function for time-invariant sy

Validation of the Rheumatoid and Arthritis Outcome Score (RAOS) for the lower extremity

BACKGROUND: Patients with inflammatory joint diseases tend due to new treatments to be more physically active; something not taken into account by currently used outcome measures. The Rheumatoid and Arthritis Outcome Score (RAOS) is an adaptation of the Knee injury and Osteoarthritis Outcome Score (KOOS) and evaluates functional limitations of importance to physically active people with inflammato

WE-14, a chromogranin A - Derived neuropeptide

The neuropeptide WE-14 is derived from the posttranslational processing of chromogranin A (CgA). While CgA is expressed in a preponderance of neuroendocrine cells, WE-14 is generated in a distinct subpopulation of CgA-immunopositive cells, most notably in the adrenal, pituitary, and parathyroid glands. Physiological and pharmacological studies have demonstrated that CgA is cleaved to generate WE-1

LHC experiments

The Large Hadron Collider (LHC) will in 2007 start colliding proton and lead beams at root(s) = 14 TeV and root(S-NN) = 5.5 TeV, respectively. The accelerator and the experiments are under construction and detailed studies of the physics program are being prepared. I will in this paper review the current status of the experiments and the heavy ion physics aspects that are unique at LHC.

Structure of reduced and oxidized manganese superoxide dismutase: A combined computational and experimental approach

Manganese superoxide dismutases catalyze the disproportionation of the superoxide radical anion to molecular oxygen and hydrogen peroxide. Recently, atomic-resolution crystal structures of the reduced and oxidized enzymes have been reported. They show an active site with the manganese ion bound to one aspartate, three histidine residues, and a solvent molecule. In this paper, we combine crystallog

On a phase diagram for random neural networks with embedded spike timing dependent plasticity

This paper presents an original mathematical framework based on graph theory which is a first attempt to investigate the dynamics of a model of neural networks with embedded spike timing dependent plasticity. The neurons correspond to integrate-and-fire units located at the vertices of a finite subset of 2D lattice. There are two types of vertices, corresponding to the inhibitory and the excitator

Barns minnesprestationer i rättsprocessen

Two important contexts for children in forensic processes are their performance in interviews and their identification performance in lineups. Another important question concerns the validity (or realism) in children’s confidence in the extent to which they correctly remember an event or a person. This paper reviews the current state of research on strengths and weaknesses in children’s testimony

Towards redox active liquid crystalline phases of lipids: a monoolein/water system with entrapped derivatives of ferrocene

The phase and electrochemical behavior of the aqueous mixtures of monoolein (MO) and synthetic ferrocene (Fc) derivatives containing long alkyl chains -(Z)-octadec-9-enoylferrocene (1), (Z)-octadecen-9-ylferrocene (2), and ferrocenylmethyl (Z)-octadec-9-enoate (3)-were studied. At low hydration, the reversed micelles (L-2 phase) and cubic Q(230) phase of MO can accommodate relatively high amounts

Blood-Graft Interactions: With special reference to cellular immune-reactivity in vascular and endovascular surgery.

Popular Abstract in Swedish Åderförkalkning i benens artärer ger upphov till "fönstertittarsjuka" och, i svåra fall, kritisk ischemi med vilosmärtor och sår eller kallbrand. I dessa sistnämnda fall är risken för en amputation stor. Kärlkirurgiska metoder med s.k. bypassoperationer användes för att söka rädda benen. För detta ändamål används helst patientens egna vener, men i vissa fall måste man aThe expression of surface adhesion molecules on white blood cells (WBC) and platelets, and the release of tumor necrosis factor-alpha (TNF-a) and interleukin-6 (IL-6) after incubation with expanded-polytetrafluoroethylene (ePTFE)- or woven Dacron grafts was determined. Both graft-materials induced alteration of the WBC adhesion molecule receptor and caused release of TNF-a and IL-6, higher for wov

Costs and quality of life associated with osteoporosis-related fractures in Sweden

This prospective observational data collection study assessed the cost and quality of life related to hip, vertebral and wrist fracture 1 year after the fracture, based on a patient sample consisting of 635 male and female patients surviving a year after fracture. Data regarding resource use and quality of life related to fractures was collected by questionnaires at baseline, 4 months and 12 month