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Neuropeptide Y-like immunoreactivity and hypertension

OBJECTIVE: Neuropeptide Y is a co-transmitter with noradrenaline in sympathetic neurons supplying arteries and veins with potent contractile effects. To investigate the role of neuropeptide Y in hypertension, we measured the circulating levels of neuropeptide Y and noradrenaline in patients with severe hypertension. DESIGN: Samples were collected from patients with untreated, severe hypertension (

A multisite study of community treatment programs for mentally ill offenders with major mental disorders - Design, measures, and the forensic sample

This article presents reasons for undertaking "The Comparative Study of the Prevention of Crime and Violence by Mentally Ill Persons" and reasons for decisions regarding the study design and choice of measures. A brief portrait of the forensic patients that have been recruited is also presented. Community treatment programs could offer long-term cost-effective care for offenders with major mental

Effects of contraction duration on low-frequency fatigue in voluntary and electrically induced exercise of quadriceps muscle in humans

The aims of this study were to investigate if low-frequency fatigue (LFF) dependent on the duration of repeated muscle contractions and to compare LFF in voluntary and electrically induced exercise. Male subjects performed three 9-min periods of repeated isometric knee extensions at 40% maximal voluntary contraction with contraction plus relaxation periods of 30 plus 60 s, 15 plus 30 s and 5 plus

Bacterial killing by heparin-binding peptides from PRELP and thrombospondin

Antimicrobial peptides (AMP) are effector molecules of the innate immune system. A cross-functionality exists between AMPs and heparin-binding peptides. Here, we show that the peptides QPTRRPRPGTGPGRRPRPRPR-P (QPT22), derived from proline arginine-rich end leucine-rich repeat protein (PRELP) and KRFKQDGGWSHWSPWSS (KRF17) from thrombospondin exert antimicrobial activities against the Gram-negative

Improved cardiac function and quality of life following upgrade to dual chamber pacing after long-term ventricular stimulation.

Aims Many patients with sinus node disease or atrioventricular block have previously received pacemakers with only ventricular stimulation (VVI or VVIR). This study aimed to investigate whether quality of life and cardiac function were affected by an upgrade to dual chamber pacing (DDDR or DDIR) following long-term ventricular stimulation. Methods After implantation of an atrial lead and a DDDR pu

Numerical and Experimental Evaluation of Springback in Advanced High Strength Steel

The automotive industry is using more and more of Advanced High Strength Steel in order to reduce the weight of the car. Since this will generate more springback, it is of vital importance to be able to predict the amount of springback in the parts. Otherwise, many late changes have to be made in order to fit the parts in their position. In order to increase the ability to understand and test the

Inactivation of TGF beta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

Specific inactivation of TGFbeta signaling in neural crest stem cells (NCSCs) results in cardiovascular defects and thymic, parathyroid, and craniofacial anomalies. All these malformations characterize DiGeorge syndrome, the most common microdeletion syndrome in humans. Consistent with a role of TGFbeta in promoting non-neural lineages in NCSCs, mutant neural crest cells migrate into the pharyngea

Reducing Moisture Transients in the Paper-Machine Drying Section with the Mid-ranging Control Technique

A new control strategy using feedback control has been developed for the multi-cylinder paper dryer configuration to reduce moisture transients in the drying section. The air system in the blow boxes was used to control the fast moisture transients in the paper machine. The new control system was combined with a previously developed physical model and was then compared with a conventional moisture

Multiscale detection of transient evoked otoacoustic emissions

This paper presents a unified approach to multiscale detection of transient evoked otoacoustic emissions (TEOAEs). Using statistical detection theory, it is shown that the optimal detector involves a time windowing operation where the window can be estimated from ensemble correlation information. The detector performs adaptive splitting of the signal into different frequency bands using either wav

Diagnostic accuracy of the neurological upper limb examination II: Relation to symptoms of patterns of findings

Background: In a sample of patients in clinical occupational medicine we have demonstrated that an upper limb neurological examination can reliably identify patterns of findings suggesting upper limb focal neuropathies. This further study aimed at approaching the diagnostic accuracy of the examination. Methods: 82 limbs were semi-quantitatively assessed by two blinded examiners ( strength in 14 in

Optical dating of young tidal sediments in the Danish Wadden Sea

We have tested the applicability of optically stimulated luminescence (OSL) to the dating of young estuarine sediments (< 1000 years) to determine whether this method can be used to complement and support existing techniques, such as Pb-210 dating. The degree of bleaching before deposition is investigated by examining the age trend in various sediment cores, and where possible, by comparison with

Korttidspsykoterapi med kvinnor och män i samband med graviditet och nyföddhetsperiod

Korttidspsykoterapi med sex kvinnor och sex män i samband med graviditets- och post partumperioden analyserades med narrativ ansats och med anknytningsteori och affektteori som grund. Syftet med studien var att skaffa kunskap om psykiska besvär hos blivande och nyblivna föräldrar och att undersöka om korttidspsykoterapi med kvinnor och män i samband med barnafödandet i förebyggande syfte kunde avl