Driven by the idea to use alarm data to explore machine learning across Industry 4.0 applications, the goal of this pilot study was to explore how to collect, store, manage and share data from the ESS Control System. Generally, we seek to make any control system data available for research and innovation but started with alarms as a feasible domain in which to explore machine learning. The goals w

The awarding of the Nobel Peace Prize 2012 to the EU (European Union) came as a surprise. Not only was the eurozone economic crisis undermining both policy effectiveness and public support for the EU, but it was also seriously challenging the EU's image in global politics. The eurozone crisis, the Nobel Prize and the search for a ‘new narrative for Europe’ demonstrate that the processes of Europea

Bisphenol A (BPA) is considered an endocrine disruptor and has been associated with deleterious effects on spermatogenesis and male fertility. Bisphenol F (BPF) and S (BPS) are struc-turally similar to BPA, but knowledge of their effects on male fertility remains limited. In this cross– sectional study, we investigated the associations between exposure to BPA, BPF, and BPS and semen quality in 556

The efficacy and side effects of endocrine therapy in breast cancer (BC) depend largely on estrogen receptor alpha (ERα) expression, the specific drug administered, and treatment scheduling. Although the benefits of endocrine therapy outweigh any adverse effects in the initial stages of BC, later- or advanced-stage tumors acquire resistance to treatments. The mechanisms underlying tumor resistance

Serotonin has been shown to affect the development of the mammalian nervous system. The serotonin transporter is a major factor in regulating extracellular serotonin levels. Using in situ hybridization histochemistry the rat serotonin transporter messenger RNA was localized during embryogenesis, the first four weeks postnatally and adulthood. Three general classes of serotonin transporter messenge

Even though co‐parenthood is one of the most significant close personal relationships that people can have, there is relatively little philosophical work on the moral duties that co‐parents owe each other. This may be due to the increasingly questionable assumption, still common in our societies, that co‐parenthood arises naturally from marriage or romantic coupledom and thus that commitment to a

This is a review of contemporary philosophical discussions of population policies. The focus is on normative justification, and the main question is whether population policies can be ethically justified. Although few analytical philosophers have directly addressed this question – it has been discussed more in other academic fields – many arguments and considerations can be placed in the analytica

Background: Early metastasis is a hallmark of small cell lung cancer (SCLC). However, the mechanisms and resulting patterns of SCLC dissemination are unclear. Our aim was thus to investigate the organ specificity and timing of blood-borne metastases in a comprehensive large cohort of SCLC patients. Methods: In this retrospective non-interventional cross-sectional study of 1009 Caucasian SCLC patie

This article discusses the concept of 'access' within ethnography. Schatz's conception of access as finding the nearest possible vantage point lays the foundation for a discussion of 15 months of fieldwork conducted in Myanmar for a study of experiences of imprisonment that had little access to the inside of these institutions. The article goes beyond an understanding of access framed by a focus o

Drawing on participatory action research conducted in Sierra Leone, Kosovo and the Philippines, Human Rights in Prisons analyses encounters between rights-based non-governmental organisations and prisons. It explores the previously under-researched perspectives of prison staff and prisoners on their lives and relationships.

An indoor localization system for positioning evacuating people can be anticipated to increase the chances of a safe evacuation and effective rescue intervention in case of a tunnel fire. Such a system may utilize prevalent wireless technologies, e.g., Bluetooth, RFID and Wi-Fi, which today are used to survey incoming and outgoing traffic to a certain space or location, to estimate group sizes and

Purpose: At the inception of the Journal of Humanitarian Logistics and Supply Chain Management (JHLSCM), logistics coordination was identified as important, both in practice and research, but few studies on the topic had been published. Ten years later, many, if not most, papers in the journal mention the topic. So the picture has changed, but to what extent? This paper discusses how coordination

THE COASTAL AREAS of the island of Gotland in the center of the Baltic Sea is an important wintering site for water-birds in Sweden. Gotland offers extensive areas of shallow feeding grounds and, due to its location, some open waters remain available even during harsh winters. Wintering waterbirds have been counted annually on the island since the start of the international waterbird counts in 196

Background: Proinflammatory mechanisms are implicated in pain states. Recent research indicates that patients with osteoarthritis (OA) with signs of central sensitization exhibit elevated cerebrospinal fluid (CSF) levels of interferon gamma-induced protein 10 (IP-10), Fms-related tyrosine kinase 1 (Flt-1), and monocyte chemoattractant protein 1 (MCP-1).Methods: The current prospective cohort study

Despite some epidemiological evidence on the protective effects of polyphenol intake on epithelial ovarian cancer (EOC) risk from case-control studies, the evidence is scarce from prospective studies and non-existent for several polyphenol classes. Therefore, we aimed to investigate the associations between the intake of total, classes and subclasses of polyphenols and EOC risk in a large prospect

WNT signalling is known to be a crucial regulator of embryonic development and tissue homeostasis. Aberrant expression of WNT signalling elements or their mutations has been implicated in carcinogenesis and/or the progression of several different cancer types. Investigations of how WNT signalling affects carcinogenesis and cancer progression have revealed that it has essential roles in the regulat