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Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies and is known for its high resistance and low response to treatment. Tumor immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Karyopherin alpha 2 (KPNA2), a member of the nuclear transporter family, is elevated in multiple human cancers and accelerates carcinogenesis. Howeve

Value Creation of Healthcare Services- Developing a Healthcare Matching Model

Healthcare in Sweden is dealing with problems regarding accessibility for patients. Moreover, there is a lack of an overall model concerning matching specialist care to patients. Against this background, the purpose was to develop a preliminary healthcare matching model and discuss the barriers of this model. Theoretically, the study draws on the concepts of matching and coordination completed wit

Tänk om vi hade Systembolaget som modell för mer svensk detaljhandel

Systembolaget kan genom sin monopolställning låta storsäljarna finansiera det udda utbudet, det lokala utbudet, personalens kompetens och ett stort samhällsansvar. Denna affärsmodell skulle med fördel till exempel kunna föras över till detaljhandel med fisk och skaldjur.

Contested values in bike-sharing mobilities – A case study from Sweden

The aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi’s What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomobThe aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi's What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomob

EXPERIMENTAL SMALL-SCALE SALT-GRADIENT SOLAR POND FOR ENERGY PRODUCTION, DEAD SEA-JORDAN

A small-scale experiment for salinity-gradient solar pond has been constructed and operated at the Dead Sea area over a period of 3 months. The pond has a volume of 5m3 with dimensions of (L, H, W) as 2.0, 2.0 and 1,25 meter respectively. The two parameters temperature and salinity concentration profiles were evaluated through the measurements of the solar pond with respect to time. The experiment

Leaving Their Mark : Using Danish Student Grade Lists to Construct a More Detailed Measure of Historical Human Capital

We provide a brief overview of the educational history of Denmark and document archival and printed sources covering the development of primary, secondary, and tertiary education. In particular, we focus on student grade lists, which are available for individuals at all levels of education from the early nineteenth century until well into the twentieth century. We suggest that these can be used to

Essays on systemic risk and financial market volatility

This doctoral thesis consists of four independent research papers. All papers are empirical and cover the area of financial market risk, with a particular focus on systemic risk and volatility in financial markets.The first paper analyzes the joint effect of centrality and other characteristics that are essential in determining banks’ systemic importance. Specifically, centrality is treated as a m