We have studied the diffusive mobility of hydrogen molecules confined in different size cages in clathrate hydrates. In clathrate hydrate H2 molecules are effectively stored by confinement in two different size cages of the nano-porous host structure with accessible volumes of about 0.50 and 0.67 nm diameters, respectively. For the processes of sorption and desorption of the stored hydrogen the di

Herein we present a chimeric recombinant spider silk protein (spidroin) whose aqueous solubility equals that of native spider silk dope and a spinning device that is based solely on aqueous buffers, shear forces and lowered pH. The process recapitulates the complex molecular mechanisms that dictate native spider silk spinning and is highly efficient; spidroin from one liter of bacterial shake-flas

Type 1 diabetes is associated with abberations of fat metabolism before and after the clinical onset of disease. It has been hypothesized that the absence of the effect of insulin in the liver contributes to reduced hepatic fat synthesis. We measured hepatic gene expression and serum metabolites before and after the onset of hyperglycemia in a BioBreeding rat model of type 1 diabetes. Functional p

We study statistical properties of the 0+ spectrum of 208Pb in the energy region Ex ≤ 20 MeV. We use the Skyrme interaction SLy4 as our model Hamiltonian to create a single-particle spectrum and to analyze excited states. The finite-rank separable approximation for the particle–hole interaction enables us to perform the calculations in large configuration spaces. We show that while the position of

This essay presents a speculative work on making distinctions among different equally valid types of research relevance. The work is innovative not only because it departs from the extant monistic perspectives, where only narrow forms of relevance are acknowledged, towards a pluralist perspective, but also because it recognizes and accounts for the plurality in the perceptions of relevance among d

Objective: European cancer survival rates vary widely. System factors, including whether or not primary care physicians (PCPs) are gatekeepers, may account for some of these differences. This study explores where patients who may have cancer are likely to present for medical care in different European countries, and how probability of presentation to a primary care clinician correlates with cancer

2.Brorson H. Circumferential suction-asssisted lipectomy is the only surgical procedure that can normalize large chronic fat-transformed lymphedemas. In: Catalano M, Pecsvarady Z, Olinic D, Wautrecht J-C, Gerotziafas G, Amann-Vesti B, Karetova D, Fagrell B, Diehm C, Kozak M, Edmonds M, editors, European Book of Angiology/Vascular Medicine. Milano, Italy: VAS, UNIMI-H Sacco; 2016. Pp XXX-XXX.

BACKGROUND: Activated protein C (APC) inhibits coagulation by degrading activated factor V (FVa) and factor VIII (FVIIIa), protein S (PS) functioning as a cofactor to APC.METHODS: By mutagenesis of the vitamin K-dependent Gla domain of APC, we have recently created an APC variant having enhanced anticoagulant activity due to increased affinity for negatively charged phospholipid membranes. In the

A computational framework for modelling damage-induced softening in fibre-reinforced materials is presented. The main aspect of this framework is the proposed non-local gradient-enhanced continuum damage formulation. At the material level, the elastic constitutive behavior is defined by a hyperelastic functional including a volumetric and an isochoric contribution. The isochoric contribution is su

Objectives: The aim of this study was to investigate the association between bisphosphonate use and the risk of new fracture in a nationwide cohort of individuals with previous hip fractures, with emphasis on individuals above 80 years of age. Design, setting, and participants: From a nationwide cohort with hip fracture (2006-2012) (n = 93, 601), each individual prescribed bisphosphonates after hi

Using Deterministic Lateral Displacement (DLD), we are able to separate bacteria by their size and their chain length. This separation enables the study of these properties as factors of virulence.

This abstract reports a novel acoustofluidic method to measure the hematocrit level of a whole blood sample within 20 seconds. The method is substantially faster than conventional centrifugation methods, has no moving parts and can be fully automated and integrated with further unit operations for analysis of blood samples at the point of care [1].

BACKGROUND: Several studies have shown associations between blood lipid levels and the risk of atrial fibrillation (AF). To test the potential effect of blood lipids with AF risk, we assessed whether previously developed lipid gene scores, used as instrumental variables, are associated with the incidence of AF in 7 large cohorts.METHODS: We analyzed 64,901 individuals of European ancestry without

Type 1 (T1D) and type 2 (T2D) diabetes share pathophysiological characteristics, yet mechanistic links have remained elusive. T1D results from autoimmune destruction of pancreatic beta cells, whereas beta cell failure in T2D is delayed and progressive. Here we find a new genetic component of diabetes susceptibility in T1D non-obese diabetic (NOD) mice, identifying immune-independent beta cell frag